Question

Discuss the benefits and risks of local and general anesthetics. What is the mechanism of action for propofol? What are the benefits of this drug? When is its use appropriate? What are the risks?

Answer 1

The complication rates are much greater in case of the general anesthesia as the body is put at a greater risk. Following a surgical procedure, patients develop respiratory problems. They are fatigued and more likely to feel nauseated. Recovery takes a long time as the body recovers from both the surgery and the anesthesia.

A patient is placed under oral or intravenous (IV) sedation incase of the local anesthesia. Local anesthesia is a much safer as compared to the general anesthesia as the body is not under stress in the way general anesthesia does. Fewer drugs are needed, during recovery. The surgical procedure is less invasive and the risks to the body diminish significantly.

The mechanism of action for propofol includes a decline in the rate of dissociation of GABA from its receptors leading to an increase in the action of the GABA activated the opening of chloride channels. Increased Satisfaction. Propofol acts quickly and sedates more predictably on a continuum, from moderate sedation to general anesthesia. Propofol can be used for inducing and maintaining sleep as part of anesthesia during surgery for adults and children 3 years of age and older. It may be used for adults before an uncomfortable procedure, for relaxing and reducing the awareness but not causing deep sleep. This is referred to as conscious sedation. Propofol can pose significant risks as it may lead to cardiac and respiratory complications, making it important that the administration of this drug be provided by a well-trained practitioner in general anesthesia, (Saraghi - ‎2013).