In: Physics
2- a) Assume the following concentrations of Na+ and K+ ions: [Na+]o = 120 mM, [Na+]i = 6 mM, [K+]o = 2 mM, and [K+]i = 150 mM. Assume further that at the peak of the action potential, pK : pNa is 1 : 12. Calculate Vm at the peak of the action potential.(Use Goldman-Hodgkin-Katz equation, disregard Chlorine ion)
b) Explain the molecular basis of the neuronal refractory periods. That is discuss both the absolute refractory period and the relative refractory period. (Discuss with regard to ion channels)