In: Biology
Why is it that so many skin infections lead to rashes as a symptom?
The skin has three layers-- * The epidermis, which is the outermost layer of skin
* The dermis, which is the second layer, and contains connective tissue, hair follicles and sweat glands.
* The hypodermis, which is the third and the deepest layer and is made of fat and connective tissue.
Our skin is the largest organ in our body and has three main functions - protection, regulation and sensation.
All the skin appendages like oil and sweat glands, hair follicles etc are found in the dermis. The epidermis does not contain any blood vessels and is mostly nourished by diffusion from the dermis.
The epidermis and dermis are separated by a thin sheet of fibres called the basement membrane and is made through the action of both tissues. The basement membrane plays a key factor in the movement of cells and molecules and also in the binding of a variety of a variety of cytokines and growth factors. It acts as a reservoir for their controlled release during physiological remodelling or repair processes. If there is any sort of skin infection, the release of substances from the basement membrane is disrupted and this is expressed as rashes on the epidermis.