Question
In: Chemistry
1. A 70 kg adult male is exposed to 0.001 ppmv of vinyl chloride (C2H3Cl) in...
1. A 70 kg adult male is exposed to 0.001 ppmv of vinyl chloride (C2H3Cl) in the air at his workplace. Note: this is far below the permissible exposure limit set by OSHA (1 ppmv).
a) Calculate this man’s lifetime cancer risk from this inhalation exposure. Assume temperature and pressure conditions of 20°C and 1 atm. Use exposure factors given in Table 6.14, and the slope factor = 0.295 (mg/kg ・ day)^-1.
b) If this man wants to limit his lifetime cancer risk from inhalation exposure to vinyl chloride to 10^-6, how many years could you work at this job?
Solutions
Expert Solution
I need all the data of the table 6.14 to calculate this. The formula that you are actually talking about is the Following:
Where:
| C | = | Concentration of the chemical in the contaminated environmental medium (soil or water) to which the person is exposed. The units are mg/kg for soil and mg/L for water. |
| IRi | = | Intake rate of the contaminated environmental medium for age bin "i". The units are mg/day for soil and L/day for water. |
| BWi | = | Body weight of the exposed person for age bin "i" (kg). |
| EFi | = | Exposure frequency for age bin "i" (days/year). This describes how often a person is likely to be exposed to the contaminated medium over the course of a typical year. |
| EDi | = | Exposure duration for age bin "i" (years). This describes how long a person is likely to be exposed to the contaminated medium during their lifetime. |
| AT | = | Averaging time (days). This term specifies the length of time over which the average dose is calculated. For quantifying cancer risk, "lifetime" exposure employs an averaging time of 70 years (i.e., 70 years × 365 days/year). |
| SF | = | Cancer slope factor (mg/kg-day)-1 |
| ADAFi | = |
Age-dependent adjustment factor for age bin "i" (unitless) |
All of these data would have to be in the table 6.14. Use those values and calculate the cancer risk.
b) For this part all you have to do is reduct the innitial concentration of 0.001 ppm to 10-6 and then, for the equation I give you before, solve for ATi. If you provide those values of the table, I can do it for you.
queen_honey_blossom answered 1 hour agoRelated Solutions
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