Which is more hydrophilic phospholipids or cholesterol? Give an explanation for your answer and use the...

Which is more hydrophilic phospholipids or cholesterol? Give an explanation for your answer and use the structures of each to help you.

Expert Solution

Hydrophilic molecules are water loving. It means they dissolve more readily in water due to their polar nature. (like dissolves like,water is polar)
Phospholipids are more hydrophilic than cholesterols because of structural differences.

Structure of phospholipids : They are of two types Glycerophospholipids and Sphingophospholipids.

Glycerophospholipids contains a glycerol molecule, two fatty acids, a phosphate group and alcohol.
Sphingolipids contains a sphingosine molecule, one fatty acid, a phosphate and a choline molecule.

Structure of Cholesterol: Cholesterol is a lipid, consisting of four linked hydrocarbon rings, a hydrocarbon tail linked to one end of the lipid and a hydroxyl group linked to the other end.

What makes phospholipid more polar?.

A molecule of Cholestrol contains only a Hydroxyl group for a Polar moiety. It otherwise contains large and bulky chains and rings of carbon and hydrogen which are highly hydrophobic.

A phospholipid molecule on the other hand contains a non polar fatty acid head but also a highly Polar Phosphate group substituted with Polar Choline/Alcohol molecule.These polar moieties impart a considerable hydrophilic character to this molecule.

gladiator answered 2 years ago

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