Question

In: Biology

1. Treatment with which of the following in neonatal (newborn) male rats would most likely lead...

1. Treatment with which of the following in neonatal (newborn) male rats would most likely lead to normal defeminization and masculinization of sexual behavior? (Assume that in adulthood all males are treated with testosterone and tested with a female.)

-Androgen receptor antagonist

-Estrogen receptor antagonist

-Alpha-fetoprotein inhibitor

-Aromatase inhibitor

-Castration

2. Phoenix et al.’s 1959 paper showed for the first time that...

-Androgen exposure during early life affects sexual behavior in adulthood.

-Estrogen exposure during early life affects sexual behavior in adulthood.

-Androgen exposure during adulthood affects sexual behavior in adulthood.

-Estrogen exposure during adulthood affects sexual behavior in adulthood.

-Pregnant females treated with androgens produce hermaphroditic offspring.

3. Which of the following is true of organizational effects on the brain in both rats and primates?

-Sexual differentiation of the brain mostly occurs before birth.

-Masculinization of the brain requires the presence of gonadal steroids.

-Feminization of the brain requires the presence of gonadal steroids.

- Masculinization of the brain requires aromatization of androgens to estrogens.

Femalesareprotectedfrommasculinizationbyalpha-fetoprotein.

Expert Solution

1. Treatment with which of the following in neonatal (newborn) male rats would most likely lead to normal defeminization and masculinization of sexual behavior
Option e.- Castration

2. Phoenix et al.’s 1959 paper showed for the first time that...

Option a.-Androgen exposure during early life affects sexual behavior in adulthood.

During specific time of developmental stages,the exposure to androgen leads to sexual dimorphic organization of the tissues responsible for the mating behavior,which in adult stage on appropraite stimulation by hormones are activated.

3. The following is true of organizational effects on the brain in both rats and primates:
Option d.-Masculinization of the brain requires aromatization of androgens to estrogens.

Testosterone is converted to estradiol by the enzyme aromatase in the brain and estradiol is responsible for some major effects of testosterone in the developing brain.

gladiator answered 4 weeks ago

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