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In: Biology

During initiation of translation: Question 6 options: both 70S and 30S ribosomal subunits must simultaneously recognize...

During initiation of translation:

Question 6 options:

both 70S and 30S ribosomal subunits must simultaneously recognize an mRNA to bind.

the initiator tRNAmet binds to the A site of a ribosome.

IF-3 must be recruited to the 30S ribosome in order for the 70S initiation complex to assemble.

specific rRNA base pairs with a sequence in mRNA to position a ribosome at the start codon.

there is no energy expenditure as the tRNA binding to mRNA is via complementary base pairing.

Solutions

Expert Solution

During translation

Initiation involves binding of small ribosomal subunit (30s) to mRNA and then is joined by 50s subunit. They don't bind simultaneously

The initiated tRNA binds directly to the P site

IF3 binds to 30S subunit and prevents premature reassociation of the large and small subunits of the ribosome.

Ribosomal binding site called is a small polypurine sequence upstream of initiation codon and is complementary to a region at the 3'end of the 16s rRNA

During translation GTP is hydrolysed when 50s subunit joins with 30s subunit to generate a complete ribosome


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