In: Nursing
which agents do the IARC classify as Group 1: Carcinogenic to humans?
A. Doxorubicin and Methotrexate.
B. Etoposide and treosulfan
C. Paclitaxel and bendamustine
D. Fluorouracil and carboplatin
Answe option B
Etoposide and treosulfan
Group 1: "The agent (mixture) is carcinogenic to humans . The exposure circumstance entails exposures that are carcinogenic to humans." "This category is used when there is sufficient evidence of carcinogenicity in humans.
methotrexate and Fluorouracil in IARC group 3 .Group 3: "The agent (mixture) is unclassifiable as to carcinogenicity in humans. " "This category is used most commonly for agents, mixtures and exposure circumstances for which the evidence of carcinogenicity is inadequate in humans and inadequate or limited in experimental animals.
doxorubicin(adriamycin) ,cisplatin (carboplatin)in agroup 2a. Group 2A: "The agent (mixture) is probably carcinogenic to humans . The exposure circumstance entails exposures that are probably carcinogenic to humans." "This category is used when there is limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in experimental animals.