In: Biology
1. What determines whether a gene allele is a risk-increasing versus a risk-decreasing allele?
2. What does it mean when we say that genetic factors influence what dose of a drug will be safest and most effective for you?
3. Imagine someone who has asthma has a direct-to-consumer test that tells him that he has risk- decreasing alleles for asthma in two of his relevant genes. How do you explain the fact that he has asthma, despite having two risk-decreasing alleles in relevant genes?
4. What does it mean to say you have a risk-increasing allele for cancer that has been reported to have 20% penetrance?
5. Why does the test that is used to determine whether a woman who has breast cancer should be prescribed Herceptin or not focus on analyzing the mRNA of the HER2 gene? What does that tell you that a DNA-level analysis would not tell you?
6. Multiple choice—Just give me the letters of your choices—no
need for explanation—there may be more than one correct answer.
Give me all that are true.
Which of the following is true regarding the effects of mutations
in the coding sequence of a gene?
A. they sometimes change the level of activity that every
individual molecule of the protein has B. they sometimes change the
overall level of activity you have of that protein in your
body
C. they sometimes change the rate at which the cell makes that
protein
7. Multiple choice—Just give me the letters of your choices—no
need for explanation—there may be more than one correct answer.
Give me all that are true.
Which of the following is true regarding the effects of mutations
in the promoter region of a gene?
A. they sometimes change the level of activity that every
individual molecule of the protein has B. they sometimes change the
overall level of activity you have of that protein in your
body
C. they sometimes change the rate at which the cell makes that
protein
ANSWER 1 :-
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