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(Dill/Bromberg 31.2) a) Use the Flory-Huggins theory to estimate the number ν(1) of configurations of a folded protein chain confined to be maximal compact, M = N. Simplify the expression using Stirling’s approximation. b) If the number of configurations of an unfolded protein chain is ν1(u) = M(z −1)N−1 (since M >> N), compute the entropy of folding ∆Sf old = kB ln " ν1(c) ν1(u)