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Between 15-30% of stroke patients develop lung infections, of which about 50% will die. Whilst preclinical...

Between 15-30% of stroke patients develop lung infections, of which about 50% will die. Whilst preclinical studies have demonstrated that acute post-stroke treatment with antibiotics significantly reduces mortality, clinical studies have found no evidence to suggest that antibiotics can improve survival. Which of the following has been proposed to be the likely explanation as to why antibiotics have not been successful? Select one:

a. Antibiotics cannot cross the blood brain barrier

b. The dose of antibiotics has not been appropriate

c. The most appropriate antibiotic(s) have not been used

d. Antibiotic treatment was administered too late

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