In: Statistics and Probability
In a study of treatments for very painful "cluster" headaches,
159159
patients were treated with oxygen and
154154
other patients were given a placebo consisting of ordinary air. Among the
159159
patients in the oxygen treatment group,
111111
were free from headaches 15 minutes after treatment. Among the
154154
patients given the placebo,
3434
were free from headaches 15 minutes after treatment. Use a
0.050.05
significance level to test the claim that the oxygen treatment is effective. Complete parts (a) through(c) below.
p1 = 111/159 = 0.6981   Sample Proportion of
oxygen treatment group free from
headache       
n1 = 159   Sample size of oxygen treatment
group       
p2 = 34/154 = 0.2208   Sample Proportion of placebo
treatment group free from
headache       
n2 = 154   Sample size of placebo treatment
group       
          
the null and alternative hypothesis are
          
Ho : p1 =
p2          
H1 : p1 >
p2                         
Whether oxygen treatment is effective than placebo
treatment       
          
This is a one sided right tailed
test          
Let α =
0.05                      
Level of
significance        
Finding the Standard
error          
We find the pooled
proportion          
p̂ =
0.4633                      
Pooled proportion       
Standard Error (SE) =
0.056378          

    where pdiff = 0 since null hypothesis
states  p1 = p2      
Zcalc =
8.4661          
          
p-value          
We find p-value such that
          
p-value = P(Z >
8.4661)          
We find p-value using z-tables or the Excel function
NORM.S.DIST          
p-value = 1 - NORM.S.DIST(8.4661,
TRUE)          
p-value = 1 -
1          
p-value =
0          
          
Decision
0 <
0.05          
p-value <
α          
Hence we reject the null
hypothesis          
Conclusion
          
Ho is
rejected          
Interpretation
:          
There exists enough statistical evidence to show that
          
proportion of patients free from headaches given oxygen treatment
is more than those given
placebo          
That is the oxygen treatment is
effective.