In: Chemistry
1. If the pO2 is 30 mmHg in a given tissue, is more or less O bound at pH 7.6 compared with that bound at pH 7.2. Explain.
2. What role does CO2 play in determining/regulating blood pH? Explain.
3. Bis-phosphoglycerate (BPG) binds to hemoglobin. Discuss where and why it binds and the effect it has on the oxygen affinity of hemoglobin.
4. Describe two similarities and two differences between myoblobin and hemoglobin.
5. When the enzyme trypsin is denatured and then renatured it only regains 8% of its activity. Why is full activity not regained as it is with RNAase?