Question

Alcohol Inhibits ADH production First briefly describe the function of ADH did explain how the ingestion of alcohol will influence both the volume a concentration of urine production

Answer 1

ADH:

Antidiuretic hormone is also known as vasopressin which is mainly formed in the hypothalamus particularly in the supraoptic nuclei of hypothalamus and it contains of nine amino acids known as polypeptide.

There are anti diuretic hormone receptors known as V1A, and V1B which increase the intracellular calcium, VV2 which increase the level of cAMP. The metabolism of the ADH (Vasopressin) occurs in the kidney and liver and has a half life of 18 minutes.

The regulation of ADH happens when the blood osmolarity increase the secretion of ADH is increased. When the extracellular fluid osmolarity increases that stimulate the osmoreceptors located in the hypothalamus which directly increase the secretion of vasopressin (ADH) Which increase the reabsorbtion of water from the kidney and the body fluid increases which results in decreased extracellular osmolarity.

The regulation of ADH flow chart:

The relation between the alcohol and increase urine concentration and volume is due to the suppression of the hormone called as vasopressin also known as anti diuretic hormone.

Alcohol is diuretic which suppresses the ADH so the kidney do not reabsorb the water. It release more amount of water which increases the volume of urine and the suppression of ADH results in increased particles in the fluid known as increased osmolarity this results in increased concentration of urine. So in this way, alcohol increases the concentration and volume of urine.

Alcohol and urine because of ADH suppression: