In: Biology
As you showed on the last exam, an experiment at U of Arkansas a couple of years ago showed that the genes for CHF and RA are linked by a distance of 10.2 cM in pigs. In order to test the linkage relationship obtained by the U of Arkansas team, a U of Missouri biology team repeated the experiment making exactly the same cross, but using independently obtained pigs.
Healthy pigs: 255
CHF: 40
RA: 44
Both CHF & RA: 261
Total: 600
Conduct a chi2 test to ascertain if there is sufficient grounds for the Missouri team to reject the Arkansas linkage value. Hint: For your expected values, use the linkage estimate provided by the Arkansas researchers to calculate what the Missouri team would have expected in their experiment. Be sure to show how you calculated your X2 value, your d.f., p-value, and conclusion from your test. For expected values use to 1 decimal, for X2 values use to 2 decimals. If you reject the Arkansas hypothesis, propose an alternative explanation
Answer-
Chi-square value = 9.79
P value is less than 0.05
So, the null hypothesis is rejected.
The explanation is given below: