In: Biology
Which one of the following factors is considered to be the major force which leads to conformational stability of globular proteins?
A. hydrogen bonding. | |
B. hydrophobic interactions. | |
C. ionic interactions. | |
D. disulfide bonding. | |
E. van der Waals forces. |
D. Disulphide bonding
The conformational stability of globular proteins depends on pH, temperature, salt concentration, disulphide bond content and amino acid sequences.
Disulphide bond is also known as S-S bond and is a covalent bond derived from two thiol(SH) groups of cysteine residues.