Question

35)Insulin resistance syndrome refers to:

   A.  
Inability to tolerate CHO, especially simple CHO

   B.  
Hyperinsulinemia

   C.  
Lipogenesis

   D.  
All of the above

36) What is the most likely cause of insulin resistance syndrome?

   A.  
Too much CHO in the diet

   B.  
Too much android (apple) fat

27) Android distribution of fat increases the incidence of all of the following except?

   A.  
HTN

   B.  
CAD

   C.  
Liver CA

   D.  
Type II DM

   C.  
Too much gynoid (pear) fat

   D.  
Too much insulin

Answer 1

INSULIN RESISTANCE SYNDROME

Insulin is secreted by the pancreas and it is a hormone which helps for the proper utilisation of the glucose by the body cells. But in certain situations, this insulin will not act effectively the cells won’t respond to insulin properly so the glucose will not get converted even if the insulin amount is normal in the body. If the glucose is not getting utilised the blood glucose level will increase and when the blood glucose level is high it will again stimulate the islets of Langerhans of the pancreas and it will produce more insulin. The production will be more and it is not getting utilised So ultimately if you are checking the Blood level the amount of insulin will be high (Hyperinsulinemia) and the amount of glucose also will be high (Hyperglycaemia). Sine the cells are not able to use the glucose we can call this intolerance to glucose. So the person will get glucose intolerance also.

This insulin resistance will be mainly for the liver cells and when the blood glucose level is increasing gradually that may leads to production of fat and lipogenesis also.

So from this it is very clear that insulin resistance is producing hyperglycaemia, intolerance to glucose hyperinsulinemia and lipogenesis .