Question

90.LDL is involved in the transport of endogenous cholesterol from tissue to the liver.

89.The synthesis of fatty acids is a reductive process. NADH provides the reducing equivalent for fat production.

88.In the biosynthesis of fatty acid, the acyl group carrier for the biosynthetic reaction is acyl carrier protein.

87.The breakdown of the fatty acid CH3CH2CH2CH2CH2CH2CH2CH2COOH via the β-oxidation pathway would yield three moles acetyl units and one mole propionyl unit.

86.In the oxidation of fatty acids, transportation of activated fatty acids into mitochondria requires the reaction with carnitine.

Answer 1

90. Statement is False.

LDL or Low density lipoprotein contains more of cholesterl than Triglycerides and proteins. It is also known as 'Bad cholesterol' as It transports cholesterol into the cells of the tissue while HDL is responsible for carrying out the 'reverse cholesterol transport' process from cells to the liver.

89. Statement is False

Fatty acid synthesis is a critical anabolic process employing NAPDH as the reducing agent. It is noteworthy that NADPH is consumed during biosynthetic reactions, whereas NADH is generated in energy-yielding reactions. Hence, It is incorrect to state that NADH acts as the reducing equivalent for fat production.

88. Statement is True

In the first step of the fatty acid synthesis, Acyl-carrier-protein(ACP) reacts with the acetyl-CoA to form the acetyl-[acyl-carrier-protein] which further leads to the chain of reactions to form the final product in the biosynthetic reaction.

87. Statement is True

In each cycle of the Beta-oxidation, one molecule of 2 carbon Acetyl-CoA is released. So, a fatty acid of 8 carbon length will generate 4 moles of acetyl CoA While in the odd-chain fatty acids, one of the end product generated is the 3 carbon Propionyl CoA. As, It is a 9 Carbon Fatty-acid, so beta-oxidation pathway will generate three moles of acetyl-CoA and one mole of Propionyl CoA.

86. Statement is True

Carnitine reacts with the acyl residues and aids in their elimination, reducing the number of acyl residues conjugated with coenzyme A (CoA) and elevating the ratio between free and acylated CoA. Thus, It plays an important role in the transfer of long-chain fatty acids into the mitochondria for beta-oxidation.