1, Most RNA viruses are single stranded and replicate in the cytoplasm while most DNA viruses...

1,

Most RNA viruses are single stranded and replicate in the cytoplasm while most DNA viruses are double stranded and replicate in the nucleus. Briefly explain why this makes sense for each of these 4 characteritics (4 points). Each of the following viruses breaks one of these (e.g. might be double stranded RNA virus). For each of these viruses say which of these it breaks (4points). Bonus points. Describe the major pathology for Molluscipox virus and B19 Parvovirus (2points).

Rotavirus

Molluscipox virus

Influenza B virus

B19 Parvovirus

Expert Solution

Characteristics of RNA and DNA virus:

RNA viruses are single-stranded: During RNA transcription, only one strand is transcribed.
RNA viruses replicate in the cytoplasm: Single-stranded RNA viruses have their genome directly translated as if it were mRNA, with host ribosomes in cytoplasm translating it into a single protein which is modified by the host and viral proteins to form the various proteins needed for replication.
DNA viruses are double-stranded:
DNA viruses replicate in the nucleus: Double-stranded DNA viruses usually enter the host nucleus for replication because they require host cell polymerases to replicate their genome.

Viruses that break these characteristics:

Rotavirus: Double-stranded RNA virus
Molluscipox virus: Double-stranded DNA virus that replicates in the cytoplasm
Influenza B virus: Single-stranded RNA virus that replicates in the nucleus.
B19 Parvovirus: Single-stranded DNA virus

Major pathology for Molluscipox virus: Molluscum contagiosum

Major pathology for B19 Parvovirus: Fifth disease or erythema infectiosum

gladiator answered 2 years ago

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