Question

1.Name the enzyme(s) that is defected in methionine metabolism

2 .Define” fast” and “Slow” protein

3. What is the difference in absorption and metabolism of Fast and Slow protein?

4.Explain what happen to protein during the postabsorptive phase, discuss the hormones involved and their role and relations in protein synthesis

5. Mary is a 25 years old postoperative patient at the health clinic on campus. With an 80gm protein intake, and a 10-gram urea nitrogen output. Please calculate Mary’s nitrogen balance status. Is she in positive, negative, or at equilibrium? Based on her nitrogen status, explain what could be the possible reason for her nitrogen status

Answer 1

1. Enzyme(s) that is defected in methionine metabolism is

Methionine Adenosyltransferase

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2. Definition of fast and slow protein

I) Fast proteins

Fast proteins are digested by the body quickly within a duration of 2 to 2 1/2 hours

II) Slow proteins

Slow proteins are digested by the body gradually over the period of 4 hours

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4. What happen to protein during the postabsorptive phase

Gluconeogenesis

Proteins are breakdown into amino acids, in that few amount of amino acids are utilized by the liver to produce glucose.

The hormones play the role protein synthesis is Growth hormone, Insulin, glucocorticoids, thyroid hormones and anabolic hormes

Growth hormones

It modulate DNA transcription and RNA translations in the cells, and facilitate protein synthesis.

Insulin

It promotes amino acids uptake into the cells, It helps to increase the polyamine formation, which in turn helps in the ribosomal RNA

Thyroid hormones

It helps in the acceleration of cell metabolism

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