GPI-AP containing membrane formation as a subcellular localization.... explain how

GPI-AP containing membrane formation as a subcellular localization....

explain how

Solutions

Expert Solution

GPI- A genuine progress indicator is a metric used to measure the economic growth of a country. GPI-anchored proteins are a class of membrane proteins containing a soluble proteins attached by a conserved posttranslational glycolipid modification the GPI anchor ,to the external leaflet of the plasma membrane.

Highlights.

* A mechanism for GPI-AP apical sorting by clustering in Microdomains is proposed.

* clustering in the Golgi regulates the apical organization of GPI-APs at the cell surface.

* GPI-AP organization in polarized epithelial cells and fibroblasts appears to be different.

GPI-AP are a class of membrane proteins containing a soluble proteins attached by a Conserved glycolipid anchor to the external leaflet of the plasma membrane.

We also underline the difference in the plasma membrane organization of GPI-APs between polarized and non-polarized cells supporting the existence of various mechanism that existence of various mechanism that control GPI-AP organization in different cell types.

gladiator answered 1 week ago

Next > < Previous

Related Solutions

In a subcellular localization technique, it is found that 50% of the protein is present at...

In a subcellular localization technique, it is found that 50% of the protein is present at the plasma membrane and 50% is in the nucleus after PAGE analysis. Propose a biological explanation for these findings.

Explain how you could use subcellular distribution data to identify the subcellular location of another enzyme...

Explain how you could use subcellular distribution data to identify the subcellular location of another enzyme for which its location is not yet known. To address this issue, discuss the extension of the experiment you are doing to determine the subcellular location of another enzyme for which you have an assay, but its specific compartmentalization in the liver tissue is not known. Include attention to both % activity and specific activity histograms in your argument. How we validate the subcellular...

1.How does the chemical structure of a Phospholipid lead to the formation of a membrane as...

1.How does the chemical structure of a Phospholipid lead to the formation of a membrane as seen in the cell? Why is this structure semi-permeable? Prokaryotes have no membrane-bound organelles. Why does the organelle membrane matter?

What is the hydrophobic effect and how does it effect membrane formation? What is its’ influence...

What is the hydrophobic effect and how does it effect membrane formation? What is its’ influence on protein folding?

Describe the structure of the cell membrane. Explain how the characteristics of the cell membrane are...

Describe the structure of the cell membrane. Explain how the characteristics of the cell membrane are ideal for its function.

why inhibitors that prevent plasma membrane localization of Ras have been used in clinical trials for...

why inhibitors that prevent plasma membrane localization of Ras have been used in clinical trials for treatment of several tumors, including colon cancer.

A membrane vesicle containing a solution with 0.25 M solute is placed into a solution containing...

A membrane vesicle containing a solution with 0.25 M solute is placed into a solution containing 0.5M solute. You may assume that the membrane is impermeable to the solute and that the external solution is so large that you cannot change it’s solute concentration. What will happen to the membrane vesicle? A. There will be no net osmosis B. It will swell due to osmosis until it’s solute concentration reaches 0.5M C. It will shrink due to osmosis until it’s...

Question