1. In an experiment, you grow E. coli cells in the lab at different temperatures. After the growth, you isolate their cell membranes, perform complete hydrolysis of their cell membranes and isolate and quantify the percentages of different fatty acids in your final sample. How would you expect the fraction of myristic acid to change as you increase the temperature?  

2. Succinyl-CoA is a negative regulator of α-ketoglutarate-dehydrogenase complex. Explain why this makes sense, and propose a possible mechanism for how this molecule inhibits citrate synthase. What other step of the citric acid cycle is inhibited by succinyl- CoA, and how do you expect that inhibition mechanism to be similar/different?

3. In gluconeogenesis, the pyruvate to phosphoenolpyruvate is one of the bypass steps that is different from the reverse reaction in glycolysis due to the irreversible nature of pyruvate kinase. There are two pathways for this bypass reaction that differ in the location where the final PEP product is synthesized – either in the mitochondria or in the cytoplasm. Assume that your cell is undergoing gluconeogenesis using pyruvate derived from the deamination of serine by the enzyme serine dehydratase:

L-serine → Pyruvate + NH3

Which of the two pathways of phosphoenolpyruvate synthesis will be used and why? What are the intermediate steps for this reaction, and where do they occur?

1.

A researcher is performing experiments on the synthesis of a membrane-bound protein (like a receptor protein). Where in the cell should he/she investigate?

Which statement about translation is NOT correct?

a. In order for translation to begin, the small ribosomal subunit must bind to the mRNA and the initiator tRNA, which is bound to methionine.

b. The initial amino acid in a polypeptide is located on the C-terminus.

c. The large ribosomal subunit is responsible for catalyzing peptide bonds between amino acids.

d. Translation is terminated when the mRNA stop codon moves into the ribosomal A site and a release factor binds in the place of tRNA.

e. At the end of termination, the small and large ribosomal subunits separate from one another, and the polypeptide is released

Digestive tract and digestive enzyme mapping:

For both example's one and two and three:

Example 1: C-ILE-LEU-VAL-ASP-GLU-CYS-TRP-GLY-LYS-PHE-ARG-N

Example 2: C-CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-N

Example 3: C-CYS-LYS-GLU-ASP-TRP-ASP-GLY-LYS-PRO-PHE-SER-ALA-N

1. take the amino acid chain in both examples and determine what digestive enzyme would be used as the protein becomes catabolized throughout the digestive tract

2. list the enzymes that will react with each amino in the protein chain

3. be sure to state where in the digestive system each phase of protein enzymatic gestation is happening.

4. putting the sequence of protein enzymatic digestion in order of movement of the protein through the digestive tract would be best for comprehension.

1) Name and classify the common amino acids according to the chemical structure of their R groups.

(Note: Please this is my Medicicinal biochemistry class question just that medicinal biochemistry is not listed among the subject then i marked this question under chemistry. Please i need an answer to this question.) show all work

All of the following is true about DNA, except __________________.

Question 10 options:

**Biochemistry**

Clearly explain how the structure of Hemoglobin is intricately connected to its function, using the principle listed below as the outline.

• The unique properties of the individual amino acids will dictate both the structure and function of a protein. (consider binding sites, active sites, placement of polar and nonpolar residues in a protein, and catalytic mechanisms.)