Your Leadership to plan and develop processes for global human resources functioning: Explain, understand, contrast and utilize best practices within the organization's domestic and global HR markets. Based on what we have studied in this course, apply HR solutions to the global market for improved functioning and outcomes to ensure mission and vision are achieved. Discuss world issues, laws, trends, and international business that may impact the effective human resources global strategy you have developed and plan to implement.

All humans share some fundamental
characteristics inherited from their Australopithecus ancestors. But humans share
more characteristics than what was listed on those slides – characteristics also shared
with most animals. One of these is the cell membrane protein ACE-2.
ACE-2 is a highly conserved protein, meaning that mutations in the ACE-2 gene are
rare. Studies of how these rare mutations are distributed across the human world
population are still in early stages (Cao et al. 2020). However, four things are clear:
1) Every human has the ACE-2 protein.
2) ACE-2 gene variations have to do with how many proteins get made (gene
expression) in the body rather than differences in the protein shape itself.
3) ACE-2 gene expression is also affected by environmental factors, including
certain medications.
4) The difference in gene expression between men and women is small; however, it is still very likely to be greater than between different geographic
populations. This is because there is more genetic variation within human populations than among human populations.
Given this information:

Do you think it is reasonable to hypothesize that SARS-CoV-2
could be a bioweapon targeted at a specific ethnic or geographic population?
Explain your answer.

0. Case #3

BlueDot Company budgeted the following manufacturing overhead costs for the 2020 fiscal year.

Accounting & finance (support department) Human resources (support department) Industrial design (operating department) Production (operating department)

$500,000 $110,000 $315,000 $175,000

Budgeted services provided by the Accounting & Finance department:

Human resources 20% Industrial design 30% Production 50%

Budgeted services provided by the Human Resources department:

Accounting & finance 15% Industrial design 65% Production 20%

Required:

1. (A) Using the information provided above, allocate costs from the supporting departments

   to the operating departments using the Direct Method.

2. (B) Ignoring your calculations in (A), use the information provided above to allocate costs

   from the supporting departments to the operating departments using the Step Down

   method with the Accounting & Finance department allocating first.

3. (C) Ignoring your calculations in (A) and (B), use the information provided above to

   allocate costs from the supporting departments to the operating departments using the

   Step Down method with the Human Resources department allocating first.

4. (D) Ignoring your calculations in (A) to (C), use the information provided above to allocate

   costs from the supporting departments to the operating departments using the Reciprocal Method using either linear equations or repeated iterations.

Humans are bipedal, terrestrial omnivores. As a species, we are adapted to a range of habitats, from deserts to mountains and from rain forests to tundra. Ultimately, however, we are descended from early hominids who evolved in African plains, and our body systems reflect this. Determine how the osmoregulatory and excretory systems of a human might be adapted if they had evolved to live in an aquatic freshwater environment.

Consider the following:

• What would be required to maintain water and salt balances, and how the osmoregulatory and excretory systems would have to change to compensate? You are encouraged to look up other (non-human; can be non-mammalian) animals that share these habitats for ideas.
• What if humans had evolved and were adapted to live in very specific habitats? In other words, it would still look *basically* like a human but would have some important differences related to its circulatory and/or breathing systems.
• What would these systems of a human that adapted to a different environment look like, and why would it look like this?
• You should consider the following parts and functions of the osmoregulatory and excretory system in your answer: Kidney – size, activity, Bladder - size, Water retention, Nitrogenous waste type (ammonia, urea, uric acid), Anything else you think is important to osmoregulatory and excretory systems.

The human resource employee recruitment and selection processes are critical to maintaining a competent and fully staffed workforce. Although these processes may have some potential weaknesses, it is incumbent upon the organization to continue to identify these issues and make any required improvements.

This discussion has four parts, as follows:

1. Think about personal experiences that you have had with a human resources department either during recruitment or the hiring process. What role did human resources play in the recruitment and selection processes? Your reply should focus on the tasks of the human resources group that would include items such as determining the need for new employees.
2. Discuss the importance of each step of the recruitment and selection processes. Based on your personal experience, what step do you think is the most important, and why? Your response should provide details of these steps and not simply list the steps.
3. From your personal experiences with the employee recruitment and selection process, what are some problems that you have seen, and what do you think could be improved?
4. Think about a time when you were interviewing for a position. What test or assessment was used during your evaluation? In your response, speak to how the assessment was done and how effective you think it was.

Email that Informs and Requests: Dress Code Controversy

As the Montreal-based director of Human Resources at Sensational, you have not have a good week. The national media recently reported the fact that Sensational- a leading women's fashion chain-has been taken before Nova Scotia Human Rights Commission to defend against a claim by a young woman . The young woman recently applied for a job at a Halifax Sensational location and was told in pre-interview with a manager that "she'd never be hired if she wore her headdress to work." Citing the Commission's website claim that "its against the law to fire an employee because she wear clothing that is required by his religion," the young woman logged a complaint. Head office in Vancouver has been in damage-control mode ever since.

Your Task: Quickly realizing the effects the negative media reporting will have, you draft an email to all employees. The purpose of the email is to reaffirm that Sensational abides by and supports all Canadian Human rights legislation and, at the same time, that employees should not talk to any media that may ask them for comments. You realize that these two messages are somewhat contradictory (one positive, one negative), but you feel time is of the essence.

Related Website: Nova Scotia Human Rights Commission (www.gov.ns.ca/humanrights)

Clarissa Clifton is a 20-something woman who spent much of the spring day working in her garden. A blustery wind caused her to unintentionally inhale the insecticide that she was spraying throughout the garden. When she began wheezing severely, she was taken to the emergency room!

The attending physician observed other symptoms including:

• Constricted pupils
• Bradycardia (slowed heart rate)

The physician prescribed administration of intravenous atropine sulfate.

1. Which division of the autonomic nervous system that releases acetylcholine (Ach) onto target effectors, is most affected in this case? Name the type of autonomic receptor that binds to Ach versus Norepinephrine. What are the subclasses for each receptor type?
   1. Atropine sulfate is the antagonist of cholinergic system. Cholinergic system is also called as Parasympathetic system. It uses Acetylcholine both as the preganglionic neurotransmitter as well as postganglionic neurotransmitter. There are two types of receptors of the parasympathetic system to where Acetylcholine binds:- muscarinic and nicotinic. Norepinephrine belongs to sympathetic system which has alpha and beta receptors. Muscarinic receptors are of 5 types:- M1, M2, M3,M4,M5. M1 act mainly on the autonomic ganglia and gastric glands. M2 receptors are mainly present on heart. M3 receptors on bronchioles, gastric smooth muscles, iris. M4 and M5 are present in CNS. Nicotinic receptors are of two types:- Nm type (neuromuscular junction) and Nn type (autonomic ganglia).
2. Insecticides contain organophosphates which inhibit acetylcholinesterase. What is the function of this enzyme? Are receptors you listed in #1 more likely to be over or under-stimulated as a result of inhaling insecticides?
   1. Organophosphates are the anticholinesterases. Cholinesterase is an enzyme which is used to hydrolyze the Acetylcholine molecule. It decreases the concentration of Acetylcholine in the synaptic cleft. Anticholinesterases inhibit the enzyme Cholinesterase and lead to increased concentration of Acetylcholine in the synaptic cleft. It leads to prolonged action of parasympathetic system. The receptors will be overstimulated as Acetylcholine remains in the synaptic cleft for long and in high concentration.
3. What are some general physiological behaviors that occur under each division of the ANS (hint what are the sayings we use to describe them)? Do the medical observations made of Clarissa support your answer to #2? Explain why/why not.
4. How would insecticides impact motor activity in the following systems or organs?
   1. Gastrointestinal tract -
   2. Sweat glands -
   3. Bronchioles (airway) -
   4. Coronary vessels (blood vessels supplying heart muscle) –

Need 3 and 4 answered (1 and 2 are answered (hopefully) correctly)

QUESTION 40

1. All of the following are part of the Social-Ecological Model except for?

   		Organizational
   		Individual
   		Public Policy
   		Nutrition Panel

2 points   

QUESTION 41

1. Health claims such as “reduces heart disease” must be evaluated by the __________ before it may appear on packaging.

   		World Health Organization (WHO)
   		US Department of Agriculture (USDA)
   		Health and Human Services (HHS)
   		Food and Drug Administration (FDA)

2 points   

QUESTION 42

1. Which group is responsible for preparing guidelines for food labeling within the food industry?

   		US Department of Agriculture (UDSA)
   		Food and Drug Administration (FDA)
   		World Health Organization (WHO)
   		Center for Disease Control and Prevention (CDC)

2 points   

QUESTION 43

1. The Mediterranean diet involves multiple ___________; moreover, ___________ is the main source of fat.

   		Herbs and spices; olive oil
   		Meats; animal fats
   		Dairy; walnut oil
   		Grains; vegetable oil

2 points   

QUESTION 44

1. The ________ of a nutrient must be established before Recommended Dietary Allowances (RDA) can be determined.

   		Acceptable Macronutrient Distribution Range (AMDR)
   		Tolerable Upper Intake Levels (UL)
   		Dietary Reference Intakes (DRI)
   		Estimated Average Requirements (EAR)

2 points   

QUESTION 45

1. The _______________ is a standardized tool which assesses whether the American diet is conforming to the Dietary Guidelines.

   		Daily Values (DV)
   		Healthy Eating Index (HEI)
   		Recommended Dietary Allowances (RDA)
   		Center for Nutrition Policy and Promotion (CNPP)

2 points   

QUESTION 46

1. Since 1980, the dietary guidelines have been reevaluated and updated every ____ years by the advisory committees of the US Department of Agriculture (USDA) and the US Department of Health and Human Services (HHS).

   		Seven
   		Five
   		Ten
   		Two

2 points   

QUESTION 47

1. A healthy eating pattern includes all of the following except:

   		Vegetables
   		Exercise
   		Grains
   		Fruits

2 points   

QUESTION 48

1. If alcohol is consumed it should be consumed in moderation – up to ______ drink per day for women and up to _____ drinks per day for men.

   		One; two
   		Four; three
   		Three; three
   		Two; three

2 points   

QUESTION 49

1. The ________ represents the recommended amount of a given nutrient based on the ______ of that nutrient in a 2,000 – kilocalorie diet.

   		Daily Value (DV); Recommended Dietary Intake (RDI)
   		Adequate Intake (AI); Tolerable Upper Intake Levels (UL)
   		Dietary Reference Intakes (DRIs); Acceptable Macronutrient Distribution Range (AMDR)
   		Recommended Dietary Allowances (RDA); Estimated Average Requirements (EAR)

2 points   

QUESTION 50

1. Oils are essential for your diet as they contain valuable essential fatty acids, but the type you choose and the amount you consume is important. You should strive for oil that is ______.

   		Plant and animal based
   		Animal based
   		Plant based
   		Manmade oils

Item 7

In the case below, the original source material is given along with a sample of student work. Determine the type of plagiarism by clicking the appropriate radio button.

Which of the following is true for the Student Version above?

Word-for-Word plagiarism

Paraphrasing plagiarism

This is not plagiarism

Hints

Item 8

In the case below, the original source material is given along with a sample of student work. Determine the type of plagiarism by clicking the appropriate radio button.

Which of the following is true for the Student Version above?

Word-for-Word plagiarism

Paraphrasing plagiarism

This is not plagiarism

Hints

Item 9

In the case below, the original source material is given along with a sample of student work. Determine the type of plagiarism by clicking the appropriate radio button.

Which of the following is true for the Student Version above?

Word-for-Word plagiarism

Paraphrasing plagiarism

This is not plagiarism

Hints

Item 10

In the case below, the original source material is given along with a sample of student work. Determine the type of plagiarism by clicking the appropriate radio button.

Which of the following is true for the Student Version above?

Word-for-Word plagiarism

Paraphrasing plagiarism

This is not plagiarism

1. If you wanted to determine whether a gene was present in a mass of DNA, what would be the best tool to use to show whether that gene was present or not?

a) Plasmid.

b) Restriction enzyme.

c) Probe.

d) Micropipette.

e) Magnifying glass.

2. If you wanted to cut a strand of DNA, what would be the best tool to use?

a) Plasmid.

b) Restriction enzyme.

c) Probe.

d) Micropipette.

e) Magnifying glass.

3. Which of the following is not a current use of DNA fingerprinting?

a) Determining paternity of offspring.

b) Determining the innocence of suspects in criminal investigations.

c) Determining the origin and nature of hides, meat, and other types of contraband.

d) Doing population surveys from animal fur or feathers.

e) Mark e if all are potential uses of DNA fingerprinting.

4.Assume that one individual is homozygous for a VNTR, and his two homologous chromosomes have a sequence of nucleotides that repeat three times on each chromosome. Another individual is heterozygous for a VNTR. One of his homologous chromosomes has a sequence of nucleotides that repeats three times, while on the other homologous chromosome the sequence repeats four times. Which statement is true if a DNA fingerprint was done on each person, and one of the genes targeted in the fingerprint is theVNTR described above? In other words the fingerprint would generate RFLP’s that included thisVNTR.

a) The individuals would produce an identical banding pattern for the RFLP’s that contain thisVNTR.

b) The individuals would produce different banding patterns for the RFLP’s that contain thisVNTR.

5. If a researcher wants to cut a gene from a sample of DNA, and put that gene into a bacterial plasmid, what should that researcher do?

a) The researcher should use a restriction enzyme to cut out the gene of interest from the DNA

sample, and use the same restriction enzyme to make a cut in plasmids. Then mix the genes and

plasmids together allowing the gene of interest to reanneal within plasmids.

b) The researcher should use a restriction enzyme to cut out the gene of interest from the DNA

sample, and use a different restriction enzyme to make a cut in plasmids. Then mix the genes and plasmids together allowing the gene of interest to reanneal within plasmids.

6. When scientists incorporate a gene into a plasmid they include a marker gene. What is the purpose of the marker gene?

a) It causes the bacterium to divide forming a colony.

b) It produces a restriction enzyme.

c) It produces a dye or in some way distinguishes bacterial colonies that have incorporated the

gene, from those that have not.

7. Which statement is not true of gene cloning?

a) It is a process to produce multiple copies of a gene.

b) It is identical to the process known as PCR.

c) It uses bacteria to make copies of genes inserted into bacterial plasmids.

8. Which of the following is a technique to incorporate “foreign” DNA into a cell?

a) Viral carriers.

b) Direct injection.

c) Gene gun.

d) Mark d if all are techniques to incorporate “foreign” DNA into a cell.

9. Which statement is true of gel electrophoresis?

a) It separates fragments of DNA according to their length.

b) The shortest strands of DNA move the slowest, and the longest strands move the fastest.

c) It is a technique to introduce mutations into DNA.

d) It is a process which causes the DNA to make millions of copies of itself.

10. Which of the following is not required for PCR?

a) RNA primers.

b) Taq polymerase.

c) Restriction enzymes.

d) DNA nucleotides (adenine, guanine, cytosine, thymine).

11. Which of the following is the most difficult to clone?

a) Carrot.

b) Frog.

c) Chimpanzee.

12. Which statement is not true of stem cells?

a) They are derived from the stems of plants.

b) They have the potential to differentiate into many types of cells.

c) They have potential value in the treatment of diseases such as Parkinson’s Disease, Alzheimer’s

Disease, and Diabetes.

d) Embryonic stem cells are pluripotent, and the most useful in disease treatment.

13. The best way to separate a mixture of DNA molecules by size is to use

a) PCR

b) Gel Electrophoresis

c) Recombinant DNA techniques

d) restriction enzymes

e) Gene cloning

14. Which statement is not true of cloning of mammals, as it was done with the sheep, Dolly?

a) The nucleus of the ovum is removed and replaced with the diploid nucleus from an adult “donor”

cell.

b) An electrical pulse triggers cleavage and development of the egg—the egg behaves as if it had

been fertilized.

c) The scientific community has complete confidence in the safety of cloning, and is ready to begin

cloning humans.

d) The clone is genetically identical to the “donor” animal, i.e. the animal that “donated” the

nucleus.

15. A DNA fingerprint can be determined using:

a) Restriction enzymes and gel electrophoresis

b) Primers and PCR

c) Recombinant DNA Technology

d) Mark "d" is both a and b are true

e) Mark "e" is both a and c are true

16. Which of the following is not a method to introduce genes into cells

a) Transduction

b) Direct injection

c) Transformation

d) Gene gun

e) Primers

17. Why does DNA migrate towards an anode during gel electrophoresis?

a) Because the deoxyribose sugars in DNA have an overall positive charge.

b) Because DNA has an overall negative charge

c) Because DNA fragments can differ by size

d) Because RFLPs differ in length for each individual

e) Mark "e" if all the above are true.

18. If you wanted to target a section of DNA with the nucleotide sequence 3'CCGTA5' you probe that is

a) 3'CCGTA5'

b) 5'CCGTA3'

c) 5'ATGCC3'

d) 3'GGCAT5'

e) 5'GGCAT3'

19. During PCR, what determines which specific section of DNA will be replicated?

a) DNA (Taq) Polymerase

b) RNA primers

c) VNTRs

d) High heat during the denaturation step

e) RNA polymerase

20. The combined DNA of two or more different species is called

a) Gene cloning

b) Restriction endonucleases

c) Recombinant DNA

d) Plasmids

e) Stem cell DNA