Competency
Identify key traditions and ideas influencing our culture.

For this assessment task, you will be required to outline how the study of Humanities enables us to learn more about how traditions and ideas influence culture. In modern times, the Humanities has come to encompass a large variety of topics, all of which reference back to culture in various aspects. The study of the Humanities is essentially a study of what makes us human. While broad in scope, its focus on critical thinking, analyzing, and the ability to reflect on one's place in the larger narrative of humankind.

In a written response of one to three pages, explain in detail what the Humanities are and how they influence culture?

a)    If you invest 70% of your funds into stock A and 30% into stock B, what is the expected return of your portfolio in each state of the economy?

b)    Use your knowledge of risk and return to explain why the portfolio is more heavily invested in Asset A (70%) than Asset B (30%).

c)     What is the overall expected portfolio rate of return?

d)    What is the standard deviation of the portfolio?

e)    Based on your knowledge of diversification, would you predict that the individual standard deviations of assets A & B be higher, lower or equal to your answer in part d above?

Problem 1

You are doing a genetics experiment with the fruit fly. In the “P” generation, you cross two true-breeding flies. Thefemale parent is brown and wingless and the male parent is black with normal wings. All of the flies in theF1 generation are brown and have normal wings.

Assume the genes are not found on a sex chromosome. Indicate the body color alleles with B and b and thewing size alleles with N and n.

a) The genotypes of the flies in the P generation are: Female:_____BBnn_________ Male:___bbNN___

b) The genotype of the flies in the F1 generation is: __BbNn___________

c) You now take an F1 female and cross her to a true-breeding black, wingless male. This male’s genotype is:_____bbnn_________

d) When the flies in (b) and (c) are mated, you count 1600 offspring in the F2 generation. If the body color geneand wing type genes are not linked, how many flies of each phenotype would you expect? (Be sure to use a Punnett square for a dihybrid cross to show your work.)

Show your work:  

Expected flies:

   _0_: # of brown, winged flies (Genotype: __BbNn__)

__800__: # of black, winged flies (Genotype: ___Bbnn___) __800___: # of black, wingless flies (Genotype: ____bbNn___) __0_____: # of brown, wingless flies(Genotype: __bbNN___)

e) When you count the F2 generation, you actually get 85 brown, winged flies, 728 black, winged flies, 712 brown,wingless flies, and 75 black, wingless flies. These results indicate that the body color and wing size are linkedgenes.

·What are the phenotypes of the recombinant flies? (Hint: Refer back to the P generation flies in the first paragraph. Recombinant flies do not resemble the original P generation phenotypes.)

·Calculate the recombination frequency (%) between the linked genes for body color and wing size.

Problem 2

You cross a true-breeding yellow-bodied, smooth-winged female fly with a true-breeding red-bodied, crinkle-winged male. The red body phenotype is dominant to the yellow body phenotype and smooth wings are dominant to crinkled wings. Use B or b for body color alleles, and W or w for wing surface alleles.

a) What are the genotypes of the P generation flies?

b) What will be the genotype(s) and phenotype(s) of the F1 offspring?

c) You discover that the genes for body color and wing surface are linked. You perform a dihybrid test crossbetween the F1 flies from part (b) with a true-breeding yellow-bodied, crinkle-winged fly. Use the followingF2 results to determine the recombination frequency (%) between the body color and wing surface genes. (Remember that the recombinants are the ones that do not resemble the parental types from the P generation.)

You decide to turn your attention to a different gene, one that controls wing length. This gene has two alleles, "L orl" where long wings are dominant to short wings. Remember that the red body phenotype is dominant to the yellow body phenotype. You again mate two true-breeding flies:

P: red-bodied, short wing male X yellow-bodied, long wing female

F1: All red-bodied, long wing

d) You perform a test cross between the F1 flies above with true-breeding yellow-bodied, short-winged flies. You get the following F2 results. What is the recombination frequency (%) between the genes for body color and winglength?

e) Based on the information in (c) and (d), what are the two possible arrangements of these three genes: body color,wing surface and wing length? Draw two linkage maps to show the possible arrangements of these genes and the map distance between genes

1. How would you “re-create” hexaploid bread wheat from Triticum tauschii (diploid) and Emmer wheat (tetraploid)?

2. Compare and contrast the origins of Turner syndrome, Williams syndrome, cri du chat syndrome, and Down syndrome. (Why are they called syndromes?)

3. Describe one human cancer (you should write about; causes, organ affected, development of the cancer, genetics of it, preventive and management measures).

4. CRISPR-Cas9 was first developed as a molecular tool in 2012; during the next few years, its use in molecular biology exploded, as scientists around the world began applying it to many different research problems, and hundreds of research papers describing its application were published. Explain why CRISPR-Cas is such a powerful tool in molecular genetics.

5. Describe in detail the CRISPR-Cas9 system of defense in bacterial against phages.

6. Describe Polymerase Chain Reaction (PCR) techniques in details. Discuss the advantages and disadvantages of PCR techniques.

7. Suppose that you have just graduated from college and have started working at a biotechnology firm. Your first job assignment is to clone the pig gene for the hormone prolactin. Assume that the pig gene for prolactin has not yet been isolated, sequenced, or mapped; however, the mouse gene for prolactin has been cloned, and the amino acid sequence of mouse prolactin is known. Briefly explain two different strategies that you might use to find and clone the pig gene for prolactin.

8. Describe how the genome of an organism of your choice has been successfully engineered to improve a trait of economic importance in the organism.

Please Use your keyboard (Don't use handwriting)

*Course Name: Ethics and Regulations in Heal PHC 216

I need new and unique answers, please. (Use your own words, don't copy and paste)

( Please i need more than 500 words please)

1: In certain cases it's legally and ethically appropriate for health professionals to proceed with a treatment without consent or proceed with a treatment that is against the patient decision, give your opinion in detail and examples.
2: What is capacity and when does an adult lack capacity
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I need new and unique answers, please. (Use your own words, don't copy and paste)

( Please i need more than 500 words please)

There are five finance questions. Please explain more detail and list your formula. Thanks

1. Sue started a retirement savings plan. At the end of each year, for 25 years, Sue deposited $4,000 to her savings plan. If the retirement savings plan earns 4 percent, compounded annually, what will her account balance equal after Sue makes the last of her 25 annual savings deposits?

2. Tom was injured by a vehicle driven by a Rapid Transit delivery driver. To settle the claim for Tom's injuries, Rapid Transit agreed to pay Tom ten annual payments of $20,000 with the first of these payments three years from today. Assuming a 4 percent annual interest rate, what is the present value of Tom's settlement?

3. To settle a wrongful death case, a judge ordered the maker of a defective product to pay the spouse of the deceased person $90,000 today, $150,000 three years from today, and $500,000 six years from today. What is the present value of the judgement against the product manufacturer, assuming a 5 percent annual interest rate? (note--the payment "today" is part of the judgement)

4. Allen would like to purchase a new home. To help fund the purchase, she will borrow $180,000 from her credit union. Jenna agreed to make monthly payments for 15 years (180 months) to repay the loan. The credit union will charge 9 percent interest, compounded monthly (0.75 percent per month). What is Jenna's monthly mortgage loan payment?

5. Jade Company borrowed money by issuing some 12-year bonds. When the bonds mature after twelve years, Harris will have to pay the maturity value, $15 million, to the bondholders. Harris Company would like to pre-fund the $15 million by setting aside an equal annual amount at the end of each year for 12 years. If the funds set aside to pre-fund the $15 million can earn 5 percent annual interest, how much must Harris Company set aside in an equal amount at the end of each year so that after 12 years it will have the money needed to pay-off the bondholders?

Imagine that the researchers in Exercise 6 conducted the same study as a repeated measures within participant design. Eight participants rated both the green and red sauces by indicating the taste scores on a 10-point scale. As in Exercise 1, researchers are concerned that the color of the green sauce will adversely affect taste scores. Use the same taste scores as in Exercise 6 to conduct your analysis.