Social Scientists have learned a tremendous amount through case studies.

For Solomon Asch's Conformity and stigma of being different provide the following:

i) A brief overview of the case study, including its participants and its results

ii) What conclusions or realizations were made as a result of the case study, what did we learn from it about human behaviour

1. Must choose one from Category (3) HUMAN DEVELOPMENT: Choose either A or B

1. Discuss how nature and nurture both contribute to ONE of the three common problems that develop in adolescence (conflict with parents, mood swings, and depression). Use examples to support your discussion. Remember that “common” means most adolescents experience it, so your examples should be taking this into consideration.

What are the most important moral considerations when using human subjects for clinical research?

Why is it difficult to justify the use of a placebo control in a trial in which a "standard-of-care" therapy already exists? Why is a placebo control easier to justify in trials in which there is no established "standard-of-care" therapy? Should those participating in a clinical trial be notified of the possibility that they may be given a placebo?

Data Mining Application

You attended a meeting with the Vila Health executive staff. During the meeting, the Human Resource Director presented a proposal to purchase and implement a sophisticated data-mining application to identify employees with high-level technical skills.

Write a post in which you discuss the pros and cons of using this type of tool. How could it be applied to the use of clinical data?

Manufacturing facilities may experience production delays due to unexpected natural events, such as fires, or anticipated, but ignored, defects or human-made problems. What are three (3) to five (5) contract clauses and/or negotiated business terms that you would want to include as the purchaser of manufactured items critical to your company's success to avoid or mitigate risks associated with production interruptions.

1. Which of the following is the best description of a genome?

a. All of the genes of an organism

b. A sequence of DNA bases that code for a particular protein

c. A single molecule of DNA

d. A duplicated chromosome formed by DNA replication

2. The end result of mitosis is

a. two cells, each with half the number of chromosomes as the mother cell.

b. two cells, each with twice the number of chromosomes as the mother cell.

c. two cells identical in genetic material, but one is smaller than the other.

d. two cells identical in size and genetic material.

3. In an adult human, where would you find active mitosis occurring?

a. Bone marrow

b. Brain

c. Muscles

d. Testes and ovaries

4. In an adult human, where would you find active meiosis occurring?

a. Muscles

b. Brain

c. Bone marrow

d. Testes and ovaries

5. If meiosis occurs in a cell with a diploid number of chromosomes of 16 how many chromosomes will be in each daughter cell?

a. 4

b. 16

c. 8

d. 2

1. The experiments that clearly showed that DNA from every organism studied had an amount of adenine equal to the amount of thymine and a cytosine content equal to the content of guanine were conducted by:

a.   E. M. Sutton.

b.   Cohen and Boyer.

c.   Hershey and Chase.

d.   Erwin Chargaff.

e.   Rosalind Franklin.

2. A quiescent (non-dividing) human cell is most likely (or most correctly described as being) in:
   1. G1.
   2. S phase.
   3. G0
   4. M phase.
   5. cytokinesis.

3. Who utilized the process of transformation, as originally demonstrated by Frederick Griffith, to provide the first solid evidence suggesting that DNA was the genetic material of living systems (in this case bacteria)?
   1. Messelson and Stahl
   2. Thomas Morgan
   3. Erwin Chargaff
   4. Hershey and Chase
   5. Avery, McCarty and Macleod

4. The two strands of a DNA helix are initially separated during the process of DNA replication by:

1. DNA polymerase I.
2. DNA polymerase III.
3. a topoisomerase.
4. primase.
5. a helicas

5. To avoid problems associated with gene dosage issues (noting that males are XY), human XX females convert one X chromosome into a/an:
   1. Barr body.
   2. centromere.
   3. centrosome.
   4. telomere.
   5. balanced translocation.

Find the human hemoglobin subunit alpha protein on PDB (Protein Data Bank) protein database. Hint: You can use also use PDB identifier “5HU6” to find human hemoglobin subunit alpha protein on PDB database.

(a) Find the Experimental Data section on this protein page and report Method and Resolution used?

(b) Find the Entry History section on this protein page and report Deposited Date and Deposition author(s)?

(c) Find the secondary structure information for this protein structure. What secondary structure types does this protein contain?

(d) How many helices are there? How many beta strands are there?

(e) Download the FASTA Sequence and Copy/Paste the sequence information from the downloaded file

(f) Click 3D View tab and view the protein structure in 3D. Then, take a screenshot of the Protein structure on the viewer and provide the screenshot

(g) Click the Sequence Similarity tab and write down how many sequences on PDB database are 70% or more similar to hemoglobin subunit alpha( it is the number is shown under “Chains in Cluster”)

You are a researcher at a small biotech company and your company has just obtained the license for use of a human GENOMIC DNA fragment putatively encoding a potentially novel protein, which is thought to regulate p53, the known tumor supressor protein. The scientists who originally cloned this GENE fragment HDM5 "claim" that HDM5 shares 90% DNA sequence homology with one of the HDM2 genes (refer to the review Levine & Oren, 2009). They propose that HDM5 may have HDM2-like properties and may be involved in regulating cell proliferation, and thus a good target to potentially develop as a cancer therapy. Your company has asked you to characterize the gene and gene products, as well as to provide an opinion as to its potential human therapeutic uses.

1. Before proceeding, you wish to know whether this gene is actually expressed in humans (your target market for therapeutic development). ?Describe, in detail, 2 efficient experimental approaches to answer this question. ?Discuss whether your proposed methods measure synthesis or accumulation of the product

Week 10 Assignment - Fiscal Planning and Management Presentation

Read and use this for this part of the assignment and do as directed please.

You are a regional healthcare administrator for a long-term care organization. You have been asked to provide training to a new group of healthcare administrators, who just completed their degree. They have no work experience in healthcare administration or financial management.

For this assignment, you are to:

1. Develop a presentation using PowerPoint slides that explain the role of healthcare administrators in fiscal planning and financial management.

Be sure to address the following components:

1. Strategic planning.

2. Budgeting.

3. Regulatory compliance.

4. Insurance and reimbursement.

5. Human resources/human capital/staffing.

2. Develop a 10–12 slide presentation with detailed speaker notes. (Your cover slide and references slide are not counted in the the 10-12 slides they are separate).

Go to Google Scholar Databases to find and include 3–5 quality references, one must be your course textbook.

Also, list references used please so they can be put on a slide.