There are different perspectives on human population growth and the dynamics associated with population change. Go to CIA World Factbook website and one developing country and compare the following and answer the questions:

Example of a developed country: China

• Population growth rate: 0.32 percent year 2020 estimation, rank 170 in the whole world
• Birth rate: 11.6 births per 1000 people 2020 estimation, rank 168 in the whole world
• Death rate: 8.2 deaths per 1000 people 2020 estimation, rank 85 in the whole world
• Net migration rate: 0.4 migrant (s) per 1000 people 2020 estimation, rank 123 in the whole world

Example of a developing country: Sudan

• Population growth rate: 2.69 percent year 2020 estimation, rank 17 in the whole world
• Birth rate: 33.8 births per 1000 people 2020 estimation, rank 23 in the whole world
• Death rate: 6.5 deaths per 1000 people 2020 estimation, rank 144 in the whole world
• Net migration rate: 0.4 migrant (s) per 1000 people 2020 estimation, rank 125 in the whole world

Please help me answer the following questions with the information I have provided above.

1.      Why do you think the population is increasing or decreasing for that country? Try to explain at least two reasons as to why this is happening?

2.      How do diseases affect the population? Can you think about any diseases that have affected the human population? (Please use peer reviewed sources to support your answer).

3.      Looking at the countries you compared, what are the toxins present in the environment that impact human health? Provide one example for each country.

A nonscientist friend of yours asks how findings in a wormorfly can be relevant to human biology. Explain to your friend the importance of model organisms in molecular biology research.

1. Compare and contast one-dimensional SDS-PAGE and two-dimensional gel electrophoresis of proteins.

2. You have purified a protein. When you subject it to SDS-PAGE, two bands are seen. Provide a possible explanation and describe how you could test your hypothesis.

3. Compare and contrast the steps in production of polyclonal and monoclonal antibodies.

4. A chromatographic column in which oligo-dT is linked to an inert substance is useful in separating eukaryotic mRNA from other RNA molecules. On what principle does this column operate?

5. You plan to use the polymerase chain reaction to amplify part of the DNA sequence shown below, using oligonucleotide primers that are hexamers matching the regions shown in red. (In practice, hexamers are too short for most purposes). State the sequence of the primer oligonucleotides that should be used, including their polarity (5?3?), and give the sequence of the DNA molecule that results from amplification.

5?-TAGGCATGCAATGGTAATTTTTCAGGAACCAGGGCCCTTAAGCCGTAGGCAT-3? 3?-ATCGGTACGTTACCATTAAAAACTCCTTGGTCCCGGGAATTCGGCATCGGTA-5?

6. Complete the incomplete diagrams below to show the key structural difference between an NTP, dNTP, and ddNTP (e.g., CTP, dCTP, ddCTP).

What do “d” and “dd” stand for?

Explain why ddNTPs are called "chain terminators" in DNA sequencing reactions.

The human resources department of a consulting firm gives a standard creativity test to a randomly selected group of new hires every year. This year, 80 new hires took the test and scored a mean of 112.9 points with a standard deviation of 13.8. Last year, 60 new hires took the test and scored a mean of 117.1 points with a standard deviation of . 15.3 Assume that the population standard deviations of the test scores of all new hires in the current year and the test scores of all new hires last year can be estimated by the sample standard deviations, as the samples used were quite large. Construct a 95% confidence interval for µ1-µ2 , the difference between the mean test score µ1 of new hires from the current year and the mean test score µ2 of new hires from last year. Then complete the table below.

Carry your intermediate computations to at least three decimal places. Round your answers to at least two decimal places.

1) Because of the mass involved in constructing and transporting a lander, the first human expedition to Mars will likely be an orbital mission. A geosynchronous orbit seems plausible, allowing astronauts in the spacecraft to have continuous line-of-sight control of rovers on the surface. What is the altitude above the surface of Mars for geosynchronous orbit? You’ll need to do some research to find the mass of Mars and its rotation period.

2) Using the expression for the escape velocity from a planet.
a) Describe the physics that went into your derivation of the escape velocity and list the formula again.
b) Use this formula to calculate the escape velocity of Mars and compare it with Earth. List the sources where you obtained the properties of each planet for your calculation.
c) What insight might you glean from the above calculation on why Mars has a thinner atmosphere than the Earth?

3) Assuming that the outer planets (Saturn, Uranus, and Neptune) are in equilibrium with the solar radiation, calculate the effective surface temperature of these 3 planets and show all intermediate steps. You can assume albedos of 0.5, 0.6, and 0.6, for Saturn, Uranus, and Neptune, respectively. The solar luminosity is 3.83 x 1026 W. How do these temperatures compare with their observed temperatures?

1. (Use Table V for this problem.) The length of human pregnancies varies according to a distribution which is approximately normal with mean 266 days and standard deviation 16 days.

(a) What percent of pregnancies last less than 240 days (about 8 months)?

(b) What percent of pregnancies last more than 270 days (about 9 months)?

(c) What percent of pregnancies last between 240 days and 270 days (about 8 to 9 months)?

(d) What is the cutoff separating the longest 20% of the pregnancies from the other 80%?

(e) What is the cutoff separating the shortest 30% of the pregnancies from the other 70%?

(f) What interval contains the middle 90% of pregnancy lengths?

1. Human Body Temperature. A sample of 115 body temperatures with a mean of 98.20℉ and a standard deviation of 0.62℉. Use a 0.05 significance level to test the claim that the mean body temperature of the population is equal to 97.6℉, as is commonly believed. Is there sufficient evidence to conclude that the common belief wrong?

2. Smartphone Users. A Ring Central survey of 395 smartphone users showed that 158 of them said that their smartphone is the only thing they could not live without. Use a 0.01 significance level to test the claim that fewer than half of smartphone users identify the smartphone as the only thing they could not live without. Do these results apply to the general population?

You are expected to prepare a human pedigree detailing the inheritance of a single
genetic disease or disorder.
The pedigree will be created from the following information:
● There are five generations.
● In generation 1, there are two families.
o family one, the male is affected; this family should be listed on the
left.
o family 2 the female is affected.
● In generation 2 there are 12 individuals. Information on this generation:
o family 1 had 7 children, family 2 had four.
o family 1 first three children were girls, the remainder boys
o family 2 had a girl, two boys, and another girl.
o the eldest female of family 1 was married.
▪ She went on to have one daughter, and then one male,
affected
o the youngest male of family 1 and the eldest female of family 2
were married. This youngest male was affected.
▪ They went on to have five children. One girl, two boys, and
two more girls. The eldest boy, and two youngest girls were
all affected.
▪ The eldest daughter went on to have a boy and a girl.
o the youngest daughter of family 1, and both males of family 2, were
affected.
● In generation 3 there are at least 9 members.
o The youngest girl of the merged family had two sons. The first died
at birth and it is unknown if he was affected. The second was
affected
o The second oldest daughter of the merged family had one affected
male. She was not married.
o A daughter was born, who was a descendant of family 1 only,
whose mother was unaffected
▪ Her father was affected.
▪ She also has an adopted brother
▪ She went on to have twin daughters
▪ She was not married
● In generation 4 there are 7 members.
o Four of five males were affected
● In generation 5 there are 2 members.
● Generation one is dead.
● Non-married partners are not included in the pedigree.
● Unless specified assume all individuals have married parents.
● Unless specified, assume all spouses are unaffected
You will provide all genotypes for the second generation and ensure all known affected
individuals are marked.

After depicting the disease on the pedigree, you should include determine its dominant
or recessive inheritance pattern, and its autosomal or sex-linked position in the human
genome. Then, you will research a condition that matches this pattern and describe it in
full. Also, you should include a brief description of the manifestations and clinical
outcomes of the disease. The written portion of the assignment should be completed in
Microsoft Word.

The human eye disease retinitis pigmentosa is caused by a loss of function mutation (rp) in the gene PRPF31. The disease is expressed when combined with wildtype allele 1 (rp+1) in a heterozygote, but not expressed when combined with wildtype allele 2 (rp+2) in a heterozygote. When comparing the number PRPF31 mRNA transcripts in the eyes of rp/rp+1 and rp/rp+2 individuals, researchers have found a higher number of functional PRPF31 mRNAs in the eyes of rp/rp+2 individuals. This is an example of ______ caused by haploinsufficiency or haplo-sufficiency________ when is rp occurs in the same genotype as rp+2.

Imagine you are the Vice President of a nonprofit, which works with human rights and equity initiatives, and you are managing the intercultural relations portfolio. Each year, you are tasked with evaluating the core values for the organization. Each cultural core value includes: acquire (knowledge), build (strategic thinking), contemplate (motivation), and do (behavior). How would you illustrate the theme of cultural experiences to members of the organization? What framework for socialization would you implement? How would you make sure that others in your organization understand racial prejudice and in the workplace?