Discuss protein binding, what it means, what are the implications of a drug protein binding percentage and how the protein binding impacts how drugs may interact with each other and the subsequent effect on the patient (provide 2 explicit examples). And, then explain what will happen if the patient is malnourished.

what are ED50 , LD50, TD50: and explain in detail why the matter. Please give 2 examples of each.

In her book, What Great Brands Do, Denise Yohn describes seven brand building principles that power great brands.

In a paper no longer than 8 pages describe how each principle applies to a company where you have worked OR (if you are not employed) a company you wish to work for in the future. Talk about how the company has used the principles (if that is true) and how they can/should use (or not use) the principles in the future. It’s alright to say they haven’t used the principle and you don’t think they need to use it going forward, but you need to explain your reasoning for stating that. You need to be very specific as to what you are suggesting. Saying “they need to carry out this principle by increasing their advertising” is not sufficient. You need to talk specifically about what type of advertising and why and what the message should be to accomplish the objective.

The paper should be a MS Word document 5-8 double-spaced pages

You are just starting a new job as investigator for the car collision investigation. You assist your superior in order to determine, as accurately as possible, the circumstances surrounding collisions (initial velocity of the vehicles involved, direction vehicles were heading, etc.) in order to determine whether the drivers at fault under the Criminal Code (dangerous driving causing death or other charges).

The weather is great and you arrive at the station as your boss tells you, “Hey, Daniel, hurry over to Jalan BBN 1/A. There has been an accident involving two cars. There are people injured.” You rush to the scene of the accident immediately. Your job is to take photos of the vehicles as they are positioned, and take a certain number of measurements, including the length of the skid marks and layout of the debris.

Your findings are as follows:
• Numerous debris (broken glass, plastic, etc.) were found at a distance of 12 m from the cars;
• The two cars stuck together (red car is heading to the black car) and there are skid marks over 12 m;
• There are also skid marks over a distance of 30 m before the debris;
• The posted speed limit on this street is 70 km/h;
• Other information: m1(red car) = 2500 kg, m2(black car) = 1100 kg.

Return to the station, your superior yells out, “Hey, Daniel, make yourself useful! Bring the friction block and spring scale, and take the measurements needed to calculate the pavement’s coefficient of friction.” Confused, but very eager, you take the heavy iron friction block, covered with tire treads, and the spring scale.

Your superior returns to you and says, “The two drivers aren’t saying much. The one in the black car was sent to the hospital. The driver in the red car is still discussing what happened, but nothing is clear!” Since you are always willing to help, you answer, “How can I help you, Sir?” Your superior’s face lights up when he hears your proposition, “Well, it’s that…, you see, we must be sure, beyond any doubt, that dangerous driving was involved… the judge needs evidence. We must gather all the necessary evidence. All I’m sure of is that, based on the skid marks, the black car was at the stop when the collision occurred. This a perfect job for an intern! Get to work! I want a full report as soon as possible”. Knowing that this information will decide whether the driver will be charged under Criminal Code, you take your role very seriously and immediately get to work.

Considering that the accident occurred in a 70 km/h zone, what do you suggest to your superior? How would you clearly explain to your superior about the method used to determine the speed of the driver at fault?

Learning outcomes:

Successful students will be able to:
1. Calculate the velocities of two vehicles before and after impact using physics principles, such as forces, motion, mechanical energy, and conservation of momentum.
2. Explain how frictional forces related to varying surfaces affect the motion of an object.

1. What is the relationship between price elasticity of demand and total revenue?

2.You are the manager of a theater. At present the theater charges the same admission price of $8 to all customers, regardless of age. You propose a two-tier pricing scheme: $5 for children under the age of 12 and $10 for adults. You tell your supervisor that your proposal is likely to increase revenue. What must be true about the price elasticity of demand if your proposal is to achieve its goal of raising revenue? Explain your answer.

3. If pilots and flight attendants agree to wage and benefit reductions in the wake of the financial difficulties in the airline industry, what impact would this have on the supply and demand in the market for airline service, assuming no other changes take place in this market?

Use your own words to explain， thank you.

Explain in your own words the tax policy reason behind section 118-195 Income tax Assessment Act 1997 with respect to deceased estates. In so doing discuss why the commissioner has been given the discretion to extend the two year period . Your answer must be supported by reference to legislation case law and tax rulings if any... note: Australian taxation law

Today, more than ever, parents are encouraged to talk to their teens about drugs. During this talk with your child, you want to present several facts. What facts about smoking, alcohol use, and marijuana use do you present to your child? Remembering that "...most adolescents think they are exceptions," and learning of generational forgetting, what approach do you use to discourage your child from using these substances?

For each of the following situations, identify the parameter being estimated and calculate anappropriate 95% confidence interval for the parameter. In your own words, interpret the interval.

1. A poll of 700 Americans is taken and they are asked to state their favorite color. 187 of those polled respond that red is their favorite color.

2. Suppose we want to estimate the average weight of an adult male in Dekalb County, Georgia. We draw a random sample of 1,000 men and weight them. We find that the average man in our sample weighs 180 pounds, and the standard deviation of the sample is 30 pounds

Explain how neutron diffusion theory is related to physical reality. Does this theory describe the actual phenomenon, or does it provide only approximation? If only an approximation, then explain what is being captured by this approximation and what is not. To get credit, you must justify your answer. State major assumptions and limitations of diffusion theory. Also, discuss potential application areas. Facilitate your discussion by providing appropriate examples

In class, we calculated the externality through tax revenues of educating a Binghamton student, assuming some parameter values (e.g. that combined state and local taxes are 12% of earnings). Your guess about those parameter values might be different from what we used in class. What’s your personal guess about the values of those parameters? Take your guess about those parameter values and calculate the size of the externality. Is the state’s subsidy of Binghamton students’ education larger or smaller than the externality through taxes? Do you think the externality through taxes is larger or smaller than the total externality?