An article included data from a survey of 2658 hiring managers and human resource professionals. The article noted that many employers are using social networks to screen job applicants and that this practice is becoming more common. Of the 2658 people who participated in the survey, 1100 indicated that they use social networking sites (such as Facebook, MySpace, and LinkedIn) to research job applicants. For the purposes of this exercise, assume that the sample is representative of hiring managers and human resource professionals.

(a)

Assuming that this sample is random/representative of the population, what other assumptions need to be true before we can create a confidence interval?

Yes, because

n ≥ 30

No, because the population distribution is not normal.    Yes, because

np̂ ≥ 10

and

n(1−p̂)≥ 10

No, because either

np̂ < 10

or

n(1−p̂) < 10

No, because

n < 30

Yes, because the population distribution is normal.

(b)

Construct a 95% confidence interval for the proportion of hiring managers and human resource professionals who use social networking sites to research job applicants. (Round your answers to three decimal places.)

   ,  

(c)

Interpret a 95% confidence interval for p, the proportion of all hiring managers and human resource professionals who use social networking sites to research job applicants

We are  % confident that the proportion of all hiring managers and human resource professionals who use  social networking sites to research job applicants is between  % and  %

(d)

Suppose that the researchers wanted to estimate the proportion of hiring managers and human resource professionals to within mean reaction time to within 1% (Round your answer up to the nearest whole number.)

n =

1. Consider the example of generic acids HZ and HD. HZ has a Ka of 3.7 x 10-10, while HD has a pKa of 11.32.

(A) Calculate/ fill in the following information: Ka HZ: Ka HD: pKa HZ: pKa HD:

(B) Which species is the stronger acid and which is the weaker acid? Which conjugate base is stronger?

2. Phenol is a weak acid that has a pKa of 9.95 and the molecular formula of C6H5OH.

(A) What is the chemical reaction of phenol reacting with water (water pKa = 15.7)?

(B) What is the Ka of phenol given its pKa is 9.95?

(C) Use the Ka expression to determine the phenol concentration in solution when [C6H5O - ] is 4.7 x 10-6 M at pH = 5.7.

(D) The structures of phenol and p-nitrophenol are given below, respectively. Given the pKa of nitrophenol is 7.1, can you offer a structural explanation for its higher acidity than phenol?

3. Using bond-line notation, draw all possible unique isomers of C6H14. Name each isomer according to IUPAC rules.

4. Provide the following structures of propane.

(A) Bond-line notation:

(B) 3D structure (wedges and dashes):

(C) Condensed structure:

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Question 891 pts

The synthesis of fatty acids is a reductive process. NADH provides the reducing equivalent for fat production.

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True

False

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Question 901 pts

LDL is involved in the transport of endogenous cholesterol from tissue to the liver.

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True

False

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Question 911 pts

The eukaryotic fatty acid synthase complex contains enzymes needed for the synthesis of palmitate.

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False

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Question 921 pts

Eicosanoids are derived from arachidonic acid.

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False

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Question 931 pts

5-phosphoribosyl-1-pyrophosphate (PRPP) is an activated form of ribose-5-P.

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False

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Question 941 pts

The conversion of IMP to AMP is involved in the salvage reactions of purine synthesis.

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False

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Question 951 pts

Nucleoside monophosphate kinase and nucleoside diphosphate kinases are involved in converting the nucleoside-5'-monophosphate (NMP) products of the purine or pyrimidine biosynthesis pathways into their 5'-triphosphate (NTP) derivatives.

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Question 961 pts

Patients with gout have elevated levels of serum uric acid.

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False

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Question 971 pts

The inhibition of xanthine oxidase activity by allopurinol will result in the accumulation of hypoxanthine and xanthine.

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False

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Question 981 pts

Metabolic specialization of organs is exemplified by the presence of glucose-6-phosphatase in the liver and kidneys but not in muscle.

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False

*Which of the following statements is true?

a. peptidoglycan is comprised of cross-linked fatty acids

b. the cell walls of most bacteria are composed of peptidoglycan

c. Gram-negative bacteria have a relatively thick layer of peptidoglycan

d. peptidoglycan is found mainly in the cell walls of fungi, algae and plants

e. answers (a) and (b) are both correct

* The cell membrane of bacteria

a. is semi-permeable.

b. is usually a lipid bilayer

c. prevents cell lysis due to high intracellular osmotic pressure

d. answers (a) and (b) are correct e. answers (a) and (c) are correct

* A bacterial species has a generation time of 15 minutes and is growing exponentially. If there are 2 cells initially how many cells are there after 90 minutes?

a. 256 b. 128 c. 64 d. 32 e. none of the above

*Most bacterial cells reproduce by

a. the budding of daughter cells from a mother cell

b. forming spores that later germinate

c. binary fission

d. production of gametes and sexual reproduction

I am going to a lab next week on Acids, Bases, PH and Buffers, but i need some help, especially on Buffers.

Q.5 Which solution(s) showed the greatest and which solutions(s) showed little or no change change in pH? Why? regarding which ones, i do understand that i need to do the lab first.

I understand bufferss resist a change in PH when a small amount of strong acid OR strong base is added to it. This means that the PH of the buffers does not change significantly (by more than 1 PH unit) when a small amount of strong acid or base its added Can you please give me an example? i dont understand when say (by more than 1 unit)

In contrast, unbuffered solutions will show significant PH changes ( greater than 1 PH unit) when a small amounts of strong acid or base are added. Can you give an example? i dont understand where it say (greater than 1 PH unit) i will appreciate your help.

Python Chemicals can be described as either acids or bases. The pH scale measures the concentration of hydrogen ions in a chemical to determine just how acidic or basic it is. For this task you are going to determine whether a chemical is acidic or basic based on its pH value, and how strongly it has that property. Remember, don't call input() or print() anywhere, just use the parameters provided and return statements.

You must have at least one conditional in each function. You cannot import any module. A couple of the tasks have individual restrictions; note them, as we will remove points for any task that does not follow the requirements.

def chemical_strength(pH): Accepts one floating point parameter for the pH value, and then:

• Determines if the pH value is valid (pH must be between 0 and 14 inclusive).

• You’ll return the string "bad measurement" if pH value doesn't make sense.

• Determines a description of the chemical based on its pH value.

  o A pH of less than 7 is an acidic chemical, however, we will be more specific:

• ▪ a pH value less than or equal to 1 is a "very strong acid"
  ▪ a pH value between 1 and 4 (exclusive) is a "strong acid"
  ▪ a pH value of exactly 4 is a "plain acid"

  ▪ a pH between 4 and 6 (exclusive) is a "weak acid"

  ▪ a pH value greater than or equal to 6 is a "very weak acid"
  o A pH of more than 7 is a basic chemical, however, we will be more specific:

  ▪ a pH value less than or equal to 8 is a "very weak base"
  ▪ a pH value between 8 and 10 (exclusive) is a "weak base"
  ▪ a pH value of exactly 10 is a "plain base"
  ▪ a pH value between 10 and 13 (exclusive) is a "strong base"▪ a pH value greater than or equal to 13 is a "very strong base"

  o If the pH is exactly 7, the chemical is simply "neutral"

• Returns the strength description as a string, e.g. "weak acid", "very strong base" etc.• Examples:

  o #pH is in between 4 and 6
  chem_strength(4.7) → 'weak acid'

  o # pH is outside of the valid pH range chem_strength(15.43) → 'bad measurement'

1. Can you make yogurt with lactose - free milk? Why?
2. Which milks are best suited to making yogurt? Which are not well - suited to making yogurt? Explain your recommendations.
3. Rennin is widely used in the food industry to make cheese. Can you explain why you can’t use the enzyme (such as rennin) to make cheese from hard boiled milk?
4. Can you still coagulate cheese protein when the pH is far lower than 4.6?  Explain your suggestions.

947.Ethanol metabolism in the liver results in the increase of the NADH/NAD⁺ ratio in the liver cytosol.

946.In gluconeogenesis, the regulatory enzyme fructose 1,6-bisphosphatase is inhibited by AMP.

945.Glucose-6-P dehydrogenase deficiency can lead to drug-induced hemolytic anemia because not enough NADH is generated.

944.Glucagon and epinephrine are similar in that both promote glycogenolysis.

943.Phosphofructokinase activity can be decreased by AMP.

942.Protein phosphatase can reverse the action of the kinase on enzymes.

Enzymes. When k2 is very small compared to k–1 the KM becomes a Kd (or in some textbooks this is called a KS ) for the ES complex. A Kd is really an equilibrium constant (Keq ) for a dissociation reaction in which the products are the dissociated form of the reactants. Write the reaction for which this Kd equals the Keq for your reaction. Make a generalization about the relationship between KM and enzyme-substrate binding affinity.

When k2 is very small compared to k1 and k–1, what process is rate determining?

What is characteristic of an enzyme-coupled receptor? How is it different from GPCRs?

Discuss the activation of a receptor tyrosine kinase and it's subsequent assembly of an intracellular signaling complex.

Describe the GTPase Ras in detail and what role does it play in regards to RTK.

Discuss the role of Ras in cancer. Is this a proto-oncogene or tumor suppressor gene and why?

What is MAP kinase? What time does it play in RTK?

Discuss the activity of the P1 3-kinase Akt with regards to apoptosis and cell survival.