Based on the Novel The Immortal Life of Henrietta Lacks using the discussion on the American Nurses Association’s Definition of Ethical Principles based on the 1990 Self Determination Act

Ethical Principles

Autonomy

Beneficence

Non maleficence

Fidelity

Justice

Paternalism

Ethical Theories

Ethical Relativism

Feminist Theory

Deontology

Utilitarianism

Apply how ethical principle were misused.

Discuss ethical theories as it applies to Henrietta and family.

Explore current research that would impact the ethical dilemmas which occurred during and after Henrietta’s life and discuss how these dilemmas would be managed in 2018.

What is the DNP relevance

Dr. Smith believes that a novel anxiety drug is detrimental to cognition. To examine this, the drug is administered to a random sample of 24 trained rats. The rats were then placed in a maze and timed on how long it took them to complete it. The average completion time was 44 seconds. Normal rats have a mean completion time of 45 seconds with a standard deviation of 14 seconds. What can be concluded with α = 0.05?

a) What is the appropriate test statistic?
---Select--- na z-test one-sample t-test independent-samples t-test related-samples t-test

b)
Population:
---Select--- time to complete maze cognition trained rats normal rats the maze
Sample:
---Select--- time to complete maze cognition trained rats normal rats the maze

c) Obtain/compute the appropriate values to make a decision about H₀.
(Hint: Make sure to write down the null and alternative hypotheses to help solve the problem.)
critical value =  ; test statistic =  
Decision:  ---Select--- Reject H0 Fail to reject H0

d) If appropriate, compute the CI. If not appropriate, input "na" for both spaces below.
[  ,  ]

e) Compute the corresponding effect size(s) and indicate magnitude(s).
If not appropriate, input and select "na" below.
d =  ;   ---Select--- na trivial effect small effect medium effect large effect
r² =  ;   ---Select--- na trivial effect small effect medium effect large effect

f) Make an interpretation based on the results.

Rats on the anxiety drug were significantly slower in completing the maze.Rats on the anxiety drug were significantly quicker in completing the maze.     The anxiety drug did not significantly impact the rats in completing the maze.

A publisher in a competitive market faces the following cost schedule for publishing a novel by one of its authors: the author is paid a $3,000,000 up-front signing bonus to write the book (it is not refundable). The going market price for a hardcover book is $32 per copy. Where Q is the number of books printed and AVC is the average variable cost of producing books at a given Q.

1. Compute total revenue, total cost and profit at each quantity.
2. Compute marginal revenue. How does marginal revenue compare to price? Explain.
3. Compute marginal cost.
4. Is there a quantity where marginal revenue and marginal cost cross? What does this signify? What is the quantity?
5. What quantity would a competitive profit maximizing publisher choose?
6. If the author were paid $4 million instead of $3 million to write the book, how would this affect the publisher’s decision on what quantity to sell and its profits?

 Hook Industries is considering the replacement of one of its old metal stamping machines. Three alternative replacement machines are under consideration. The relevant cash flows associated with each are shown in the following​ table:. The​ firm's cost of capital is 9​%.

a.  Calculate the net present value (NPV​) of each press.

b.  Using​ NPV, evaluate the acceptability of each press.

c.  Rank the presses from best to worst using NPV.

d.  Calculate the profitability index​ (PI) for each press.

e.  Rank the presses from best to worst using PI.

Massey Machine Shop is considering a four-year project to improve its production efficiency. Six months ago, it contracted with Dr. Wright to provide a thorough study of whether there was a need for this four-year efficiency project. The report was delivered one month ago and it’s cost was $30,000. The report suggests that the company should go ahead with the project subject to Massey’s financial analysis. Buying a new machine press for $450,000 is estimated to result in $120,000 in annual pretax cost savings. The press falls in the MACRS five-year class and it will have a salvage value at the end of the project of $85,000. At time 0, the press will also require an additional investment in inventory of $9,000. Meanwhile, the accounts payable will increase by $3000. Every other current accounts remain the same. If the company’s tax rate is 20% and the discount rate is 12%, should the company accept the project? (30 pts). The MACRS schedule is as follows:

Massey Machine Shop is considering a four-year project to improve its production efficiency. Six months ago, it contracted with Dr. Wright to provide a thorough study of whether there was a need for this four-year efficiency project. The report was delivered one month ago and it’s cost was $30,000. The report suggests that the company should go ahead with the project subject to Massey’s financial analysis. Buying a new machine press for $450,000 is estimated to result in $120,000 in annual pretax cost savings. The press falls in the MACRS five-year class and it will have a salvage value at the end of the project of $85,000. At time 0, the press will also require an additional investment in inventory of $9,000. Meanwhile, the accounts payable will increase by $3000. Every other current accounts remain the same. If the company’s tax rate is 20% and the discount rate is 12%, should the company accept the project?   (30 pts). The MACRS schedule is as follows:

Question 58

Marigold, a large manufacturing company, currently uses a large printing press in its operations and is considering two replacements: the PDX341 and PDW581. The PDX costs $480,000 and has annual maintenance costs of $8,000 for the first 5 years and $13,000 for the next 10 years. After 15 years, the PDX will be scrapped (salvage value is zero). In contrast, the PDW can be acquired for $120,000 and requires maintenance of $26,000 a year for its 10-year life. The salvage value of the PDW is expected to be zero in 10 years. Assuming that Marigold must replace its current printing press (it has stopped functioning), it has a 9-percent cost of capital, and all cash flows are after tax, which replacement press is the most appropriate? (Round answers to 2 decimal places, e.g. 125.25.)

Chain Replication Approach:

Equivalent Annual NPV Approach:

10. In a study conducted to determine whether the role that sleep disorders play in academic performance, researcher conducted a survey of 1800 college students to determine if they had a sleep disorder. Of the 500 students with a sleep disorder, the mean GPA was 2.51 with a standard deviation of 0.85. Of the 1300 students without a sleep disorder, the mean GPA is 2.85 with a standard deviation of 0.78. Test the claim that sleep disorder adversely affects one’s GPA at the 0.05 level of significance?

11. In one experiment, the participant must press a key on seeming a blue screen and reaction time (in seconds) to press the key is measured. The same person is then asked to press a key on seeing a red screen, again with reaction time measured. The results for six randomly sampled study participants are as follows:

Participant

1

2

3

4

5

6

Blue

0.582

0.481

0.841

0.267

0.685

0.450

Red

0.408

0.407

0.542

0.402

0.456

0.522

Construct a 99% confidence interval about the population mean difference. Assume the differences are approximately normally distributed.

According to the National Bureau of Economic Research, the lengths of business cycles from 1919 to 1995, measured from trough to trough (a trough is the low point) in months, were 61 38 46 50 74 73 98 58 65 44 127 62 74 38 110 57 Find the Standard Deviation, mean, median, mode, and midrange

The focus of this question is to analyse the external operating environment of a Higher Education (HE) Sector and discuss potential impacts on the HRM functions of a HE provider such as a University. Use Jackson and Schuler (1995) HRM model to analyse the external environment of the HE Sector that you are familiar with. Identify and discuss the factors of the environment and their potential impact on the HRM functions of an HE provider of your choice.