Questions
Cycling. For a touring bicyclist the drag coefficient C1ƒ = 1 CArv22 is 1.00, the frontal...

Cycling. For a touring bicyclist the drag coefficient C1ƒ = 1 CArv22 is 1.00, the frontal area A is 0.463 m^2, and the coefficient of rolling friction is 0.0045. The rider has mass 50.0 kg, and her bike has mass 12.0 kg. (a) To maintain a speed of 12.0 m/s (about 27 mi/h) on a level road, what must the rider’s power output to the rear wheel be? (b) For racing, the same rider uses a different bike with coefficient of rolling friction 0.0030 and mass 9.00 kg. She also crouches down, reducing her drag coefficient to 0.88 and reducing her frontal area to 0.366 m^2. What must her power output to the rear wheel be then to maintain a speed of 12.0 m/s? (c) For the situation in part (b), what power output is required to maintain a speed of 6.0 m/s? Note the great drop in power requirement when the speed is only halved. (For more on aerodynamic speed limitations for a wide variety of human-powered vehicles, see “The Aerodynamics of Human-Powered Land Vehicles,” Scientific American, December 1983.)

In: Physics

- It is often easier to see manifestations of women’s oppression in cultures other than our...

- It is often easier to see manifestations of women’s oppression in cultures other than our own, since they don’t seem “natural” to us. However, as we have seen in class, for every issue we have located in “other cultures” we can find an analogous manifestation in the culture(s) of the United States that reveals a shared rootedness in patriarchal society. Offer and explain U.S. analogues to three of the following: stark division of gender roles, son preference, child marriage, and control of women’s sexuality.

-Discuss the origins of human rights discourse and the extent to which it has been applied (or not) to women’s issues we have discussed in class. Provide examples of how women’s lives (stories, issues, voices, ideas) continue to be "silenced" around the world.

- Family has been described as a “mythical haven.” Even though many of us find love and support among and within our families, statistically, it can be a dangerous place for women around the globe and in the U.S. How exactly is it “dangerous” in the context of women’s human rights? Why is it difficult to make motherhood, marriage and family “safe spaces” for women?

In: Psychology

Henry Thomas Throckmorton was born at 2:06 this morning at Atherton Memorial Hospital. Henry weighed 8...

Henry Thomas Throckmorton was born at 2:06 this morning at Atherton Memorial Hospital. Henry weighed 8 pounds, 2 ounces, and is 22 inches long. He appears to be a healthy and normal human infant. What is the basic nature of human personality? What influences will shape little Henry’s personality? How will his parents influence the development of his personality? Imagine that you have asked these questions of three psychologists, one representing Freud and psychoanalytic psychology, the second representing Skinner and the radical behaviorists, and the third representing Carl Rogers, Abraham Maslow, and humanistic psychology. Please respond to the prompts. Please post your original discussion by Wednesday and reply to at least three of your classmates' original discussions over 3 - 5 different days of the week by Sunday, 11:55p. Please reply to my posting changing my name to your last name in the subject. When replying to your classmates’ original discussions please do not change the title in the subject including their last name. This is a question and answer forum. In order to see other responses to these questions, you must first post your answer

In: Psychology

Antibiotics are used to treat a wide variety of bacterial infections and have saved millions of...

Antibiotics are used to treat a wide variety of bacterial infections and have saved millions of lives since they were first introduced in the 1940s and 1950s. However, due to both overuse and misuse, many are no longer effective and The World Health Organisation (WHO) considers the emergence of new antibiotic-resistant bacteria to be a serious threat to global public health.

According to their mechanism of action, antibiotics can be divided into three main groups, those inhibiting cell wall synthesis, those inhibiting protein synthesis and those that inhibit nucleic acid synthesis. For example, penicillin and its related compounds prevent susceptible bacteria from creating a cell wall. They do this by binding to and inactivating an enzyme (transpeptidase) necessary for the cross-linking of peptidoglycan in the wall, thus stopping its formation. Resistance to this antibiotic is due to the bacteria producing its own enzyme called beta-lactamase which breaks the ring structure of the penicillin and prevents its ability to bind to the bacterial transpeptidase.

As with all proteins, beta-lactamase is encoded by a section of DNA – but how does that DNA and the ability to produce a new protein transfer from one population of bacteria that have resistance to another population that don’t?

Other than direct transfer from parent to daughter cell, horizontal transmission of DNA between different genomes also occurs. Horizontal gene transfer is made possible by the existence of mobile genetic elements, such as plasmids (extrachromosomal genetic material), transposons (“jumping genes”) and bacteria-infecting viruses (bacteriophages). These elements are transferred between organisms through different mechanisms, which in prokaryotes include transformation, conjugation, and transduction.

  • Write a sentence for each of these mechanisms describing the manner in which the DNA can be transferred from one cell to another.
  • Choose a disease or an organism that has a well-documented mechanism of resistance (such as methicillin resistant Staphylococcus aureus - MRSA or tuberculosis) and see if you can identify the gene or genes that confer resistance and the method of DNA transfer thought to contribute to its spread. This may be from one organism to another or may simply be passed down from mother to daughter cell due to environmental pressure.
  • Finally, discuss the danger that antibiotic resistance poses in today’s society, consider how man has contributed to this and suggest any strategies that you think may be able to halt it or prevent its expansion

In: Biology

Chapter 6 – Where it Starts - Photosynthesis * Section 6.1 – Overview of Photosynthesis o...

Chapter 6 – Where it Starts - Photosynthesis
* Section 6.1 – Overview of Photosynthesis
o Apply the terms autotrophs and heterotrophs to the previously learned terms of producer and consumer. Going forward, autotrophs and heterotrophs are the terms you should use.
o How does the textbook define photosynthesis? From this textbook definition, what is the purpose (useful product) of photosynthesis?
o What are the names of each of the two sets of reactions in which photosynthesis occurs?
o Memorize the summary equation of photosynthesis. What goes in (reactants)? What comes out (products)?
o Be able to label the main parts of a chloroplast (figure 6.3 of your textbook)
o Where does the first set of photosynthetic reactions occur in a chloroplast? Where in the chloroplast does the last set of reactions occur?
* Section 6.2 – Sunlight as an Energy Source
o Explain the experiment by Theodor Engelmann. How did it work (Describe the set up)? What did he discover?
o What is a pigment? How is it involved in photosynthesis?
o Which pigment is most common in plants?
o What is an accessory pigment? How can this describe why many leaves change color in autumn?
* Section 6.3 – Light-Dependent Reactions
o What is a photosystem?
o In the non-cyclic pathway of light-dependent reactions, how many times is light required?   
o Look at figure 6.8 in your textbook (light-dependent non cyclic pathway). Understand that all of these motions and steps are working to build up Hydrogen ions inside the thylakoid compartment in large amounts, so that they naturally want to diffuse out of this space (like a inflated balloon wanting to burst). When the hydrogens flow out, they flow through the ATP synthase enzyme, and the flow of the ions powers the ATP synthase enzyme to do work. What work is it actually doing?
o Calvin-Benson Cycle (aka – light independent reactions). What goes in at the beginning? What comes out? Where do the carbon atoms in the sugar that is produced in photosynthesis come from (where do the plants get the carbon atoms)?
o What are stomata and why are they important for plants?
o Where do you find C4 plants? How about CAM plants? How do each of these types of plants perform photosynthesis differently so that they can survive in their environments?

In: Biology

Pat plans to begin his consulting business on 1 Jan 2023. He is provided with the...

Pat plans to begin his consulting business on 1 Jan 2023. He is provided with the projected data for the first 2 years. He expects to pay a 30% income tax after each year.

Construct the balance statement for the year 2024.

Transactions

01-January-2023 Open business bank account with transfer of personal funds 450000
01-January-2023 EFT for rental of office space. Immediate occupancy. 60 months at $4500 per month. 270000
01-January-2023 Office equipment purchased for cash to get discount from the retail price of $67,000. 60000
01-January-2023 Office equipment to be replaced in 5 years. Expect to get $6,000 for old equipment. 6000
03-January-2023 Bank loan approved and credited to account. Payable in 2026 300000
30-March-2023 Credit sales. EFT payment to be received in 90 days. 51500
06-April-2023 Employee timesheets submitted for work performed. Payment (EFT) to be made in 7 days. 7800
24-April-2023 Cash sales. 25500
01-May-2023 Purchased supplies on credit from Office Works. 33000
15-December-2023 Credit sales. EFT payment to be received in 90 days. 44000
28-December-2023 Employee timesheets submitted for work performed. Payment (EFT) to be made in 7 days. 8580
31-December-2023 Recorded estimate for electricity expense. Bill not yet received. 6500
31-December-2023 Count of supplies revealed showed amount on hand at year-end of … 9900
03-April-2024 Credit sales. EFT payment to be received in 90 days. 30000
09-April-2024 Employee timesheets submitted for work performed. Payment (EFT) to be made in 7 days. 5600
14-April-2024 Cash sales. 53000
03-May-2024 Purchased supplies on credit from Office Works. 36000
05-May-2024 Used excess cash to make partial repayment on bank loan. 49000
20-December-2024 Credit sales. EFT payment to be received in 90 days. 36000
25-December-2024 Employee timesheets submitted for work performed. Payment (EFT) to be made in 7 days. 6160
31-December-2024 Recorded estimate for electricity expense. Bill not yet received. 7150
31-December-2024 Count of supplies revealed showed amount on hand at year-end of … 10800

cost of supplies is the supplies spent on credit

In: Accounting

1. Discuss what the following errors or changes in procedure will have on your titration and...

1. Discuss what the following errors or changes in procedure will have on your titration and on the calculated molar mass of your acid

a.Reached the endpoint prior to all of the acid dissolving.

b.You stopped the titration and recorded the final buret volume when a deep

pink/red color was seen.

c.You used twice the amount of water to dissolve the acid.

**Correct answers will clearly state if the calculated molar mass is higher or lower than the correct value or if there is no effect.

2. What if the unknown acid was really a triprotic acid (three H+ ions to be donated) instead of a diprotic acid

a. Write the formula for the triprotic acid and a balanced equation for the titration reaction.

b. Using your experimental data from trial #2 (assuming the acid mass is really that of the triprotic acid), calculate the molar mass of the triprotic acid.

c. Compare the calculated molar masses of the triprotic acid with the diprotic acid molar mass.

3. Consult the supplemental page on Canvas with a list of possible diprotic acids. Using molar masses, what is/are the most likely identity(ies) of the unknown acid?

In: Chemistry

Malaria is a disease that is caused by the eukaryotic parasite Plasmodium and is transmitted between...

Malaria is a disease that is caused by the eukaryotic parasite Plasmodium and is transmitted between individuals by the bite of infected mosquitoes. Different species of Plasmodium cause disease in different vertebrate species, but in all cases the parasite infects and destroys red blood cells. The repeated emergence of drug-resistant strains of Plasmodium parasites responsible for human infections has caused researchers to continually search for new drugs or combinations of drugs that can provide an effective treatment. A drug that has proven effective in recent years is artesunate, but now artesunate-resistant Plasmodium strains have also appeared.

Researchers investigated whether artesunate-resistant Plasmodium strains could be effectively treated by other drugs. In a mouse model of malaria, the researchers determined that a particular strain of artesunate-sensitive Plasmodium (ART-S) could be largely eliminated from the mice at a dose of 0.15 mg/kg. By repeated exposure of the artesunate-sensitive strain ART-S to increasing concentrations of artesunate, the researchers developed a Plasmodium strain that is highly resistant to artesunate (ART-R) and requires a minimum dose of 240 mg/kg to eliminate the parasites.

The researchers then compared how effectively several common antimalarial drugs eliminate the ART-S and ART-R strains in vitro. The researchers infected human red blood cells with the ART-S and ART-R Plasmodium strains and incubated the infected cells in tissue culture medium. They added serial dilutions of the drugs to replicate cultures and determined the IC50 for each drug, the concentration of the drug that reduced the parasite load in the red blood cells by 50% (Table 1).

Table 1. IC50 for common antimalarial drugs tested on artesunate-sensitive (ART-S) and artesunate-resistant (ART-R) Plasmodium strains

Drug ART-S: IC50±2SEx¯ (nM) ART-R: IC50±2SEx¯ (nM)
Amodiaquine 11.3 (0.8) 132.4 (16.9)
Chloroquine 50.1 (3.6) 53.0 (11.3)
DHA 13.8 (0.7) 49.5 (6.8)
Mefloquine 41.7 (2.7) 39.1 (5.4)
Quinine 49.7 (3.1) 216.9 (81)

1. Plasmodium is an organism with both sexual and asexual life cycles. Describe the most likely cause of a heritable phenotypic change in some members of a population of asexually reproducing organisms. Explain how repeated exposure of the artesunate-sensitive Plasmodium strain to increasing concentrations of artesunate led to the development of the artesunate-resistant Plasmodium strain.

2. Based on the data, identify the drug that, from the ART-S strain to the ART-R strain, has the largest relative increase in the IC50. Based on the information provided about the mouse model, calculate how many times more sensitive the originalART-S Plasmodium strain is to artesunate than is the ART-R strain.

3. In the mouse model of malaria, the researchers injected Plasmodium-infected human red blood cells into the mice because the Plasmodium species had surface ligand proteins that bound only to cell membrane proteins of human red blood cells. Assume that the researchers noticed that some of the parasites no longer infected human red blood cells but instead infected mouse red blood cells. Predict the most likely cause of this change in the host specificity of the parasites. Plasmodiumreproduces both sexually in the host vertebrate and asexually in mosquitoes. The researchers claim that the Plasmodium organisms that infect the two different types of red blood cells are likely to evolve into two separate species of Plasmodium. Based on the biological species concept, provide reasoning that would support the researchers’ claim.

In: Biology

1) What were the primary standards used for each standardization? Could you use them interchangeably? Why...

1) What were the primary standards used for each standardization? Could you use them interchangeably? Why should we pay attention to the mass of the primary standard in the standardization of NaOH and HCl?

2) Why do we boil and then cool the distilled water before preparation of NaOH? Why this process is not necessary for the preparation of HCl?

3) In the titration of weak acid with a strong base why did you use phenolphthalein as indicator?

4) For the titration of a strong acid a neutral range indicator is used and for the titration of weak acids a basic range indicator is used. However, for the titration of their mixture you used an indicator of acidic range for the first end-point. Why?

5) Is volumetric titration or gravimetric titration more accurate? Which one is more precise? Discuss the differences. (Try to use your replicate data and the standard deviation)

6) What are the sources of error in gravimetric titration vs. volumetric titration? Which one would be more dominant?

7) Consider automating a volumetric titration vs. a gravimetric titration, which one would be easier to do?

In: Chemistry

1. Solutions are comprised of a solute and a solvent. Explain what makes a solution different...

1. Solutions are comprised of a solute and a solvent. Explain what makes a solution different than the generalized term “mixture.” What is meant by solute and solvent? Give three different examples of a solute and solvent coming together to form a solution. Do not use salt water as an example, and provide at least one non-aqueous solution.


Explain what is meant by an electrolyte, and how one can tell if a material would be a strong, weak, or non-electrolyte. Are acids and bases electrolytes? If so, are they a strong or a weak electrolyte – or does it depend on the acid/base?

2. Solubility rules are generally defined for us in tables. Please re-summarize the tables provided in the text (or from an online source if you do not have the textbook). What happens when you mix compounds in solution and they form a compound that is insoluble? Is there a general name for this type of chemical reaction?

Instead of writing out molecular equations – sometimes we are able to write a reaction of interest out in terms of just the ions that participate in the reaction. Write out the net ionic equation for the reaction of Lead (II) Nitrate and Potassium Chloride.

In: Chemistry