#1. Heparin is a polyanionic polysaccharide that blocks initiation by RNA polymerase by virtue of its binding to double stranded DNA. However, Heparin inhibits only when added before the onset of transcription, and not if added after transcription begins. Explain the difference.
#2. Describe how RNA Polymerase backtracking could function to increase the fidelity of transcription.
In: Biology
Calculate the pH of 100.0 mL of a buffer that is 0.0850 M NH4Cl and 0.180 M NH3 before and after the addition of 1.00 mL of 5.50 M HNO3.
Can you please do a step-by-step of how to solve this, paying special attention to how to get the Ka in the Henderson Hasselbalch Equation? That's the part I'm not understanding.
In: Chemistry
Provide a brief history of Standard Oil Co Inc (owned by John D. Rockerfeller) and of how antitrust issues led to its break up; discuss the market structure both before and after the break up(i.e., using the characteristics of market structures); explain how the nature of goods and services the firm provides to the marketplace have changed.
In: Economics
Calculate the pH of 0.305 L of a 0.17 M acetic acid - 0.28 M sodium acetate buffer before (pH1) and after (pH2) the addition of 0.0062 mol of HBr. Assume that the volume remains constant. (Ka of acetic acid is 1.8⋅10−5)
Express your answers using three significant figures separated by commas.
In: Chemistry
A family took a 20 year mortgage of $195,000 at 5.75% per year compounded monthly. Immediately after the 85th monthly payment, they decided to re-finance this mortgage because they found a lower rate of 3.75% per month compounded monthly. If they continue the same amount of monthly payments as before, how long will it take to pay off this mortgage?
In: Economics
A family took a 20 year mortgage of $195,000 at 5.75% per year compounded monthly. Immediately after the 85th monthly payment, they decided to re-finance this mortgage because they found a lower rate of 3.75% per month compounded monthly. If they continue the same amount of monthly payments as before, how long will it take to pay off this mortgage?
In: Economics
1)A 21.7 mL sample of 0.267 M dimethylamine, (CH3)2NH, is titrated with 0.241 M perchloric acid. The pH before the addition of any perchloric acid is
2)A 27.1 mL sample of 0.212 M dimethylamine, (CH3)2NH, is titrated with 0.201 M hydroiodic acid. After adding 40.6 mL of hydroiodic acid, the pH is
In: Chemistry
Suppose we titrate 20.0 mL of 0.100 M HCHO2 (Ka = 1.8 × 10–4) with 0.100 M NaOH. Calculate the pH. Before any base is added: pH = When half of the HCHO2 has been neutralized: pH = After a total of 15.0 mL of base has been added: pH = At the equivalence point: pH =
In: Chemistry
When doing Paper Chromatography,
1.What would you expect to see if the paper had been touched by fingers after developing with solvent, but before staining with ninhydrin?
2.Why does the filter paper need to be stapled so that the edges do not touch each other? What would occur if it were done incorrectly?
In: Chemistry
A firm has a debt-to-value ratio of 1/3. It has only debt and equity in its capital structure. Its before tax cost of debt is 9% and the after tax weighted average cost of capital (WACCAT) is 12%. What is the firm’s cost of equity if the tax rate for the firm is 35%?
16.050%
15.075%
none of these
18.000%
9.000%
In: Finance