1.Normal fertilization requires changes in the membrane organization of both sperm and oocyte and penetration of the oocyte by a single spermatozoon.
a. What physical, cellular and biochemical molecular processes are necessary for the succesful passage of a spem from the outermost portion of the cumulus oophorus to the oocyte membrane?
b. How does the human sperm nucleus move in the cytoplasm and why does it facilitate the juxtaposition of the material and paternal pronuclei?
c. why is the orientation of pronuclear DNA critical for embryogenesis to proceed and how does it promote pronuclear membrane breakdown (syngamy)
d. What specific defects in the above processes have been shown to result in fertilization or early developmental failure?
In: Biology
We have a controller, and every time the Operator changes the Set Point, the controller responds, and gets the process sorted out. Now, somewhere, we have read that load disturbances needed to be considered in processes, as well. How will this controller react, if there is a load disturbance, and not a Set Point change? provide a basic answer to this.
In: Electrical Engineering
A medical researcher believes that a drug changes the body's temperature. Seven test subjects are randomly selected and the body temperature of each is measured. The subjects are then given the drug, and after 3030 minutes, the body temperature of each is measured again. The results are listed in the table below. Is there enough evidence to conclude that the drug changes the body's temperature?
Let d=(body temperature after taking drug)−(body temperature before taking drug)d=(body temperature after taking drug)−(body temperature before taking drug). Use a significance level of α=0.02 for the test. Assume that the body temperatures are normally distributed for the population of people both before and after taking the drug.
| Subject | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
| Temperature (before) | 100.4 | 99.3 | 97.6 | 100.7 | 99.6 | 99.7 | 98.9 |
| Temperature (after) | 100.1 | 98.8 | 98 | 100.3 | 99.2 | 99.2 | 98.7 |
Copy Data
Step 4 of 5 :
Find the p-value for the hypothesis test. Round your answer to four decimal places.
In: Statistics and Probability
Discuss the changes in which this concept has undergone through development of public policy area. The concepts that you can choose such as; agenda setting, policy formulation, policy implementation, policy evaluation, policy change and policy termination.
In: Economics
Presented below are changes in all the account balances of Cord
Furniture Co. during the current year, except for retained
earnings.
|
Increase |
Increase |
|||||||
| Cash | $70,960 | Accounts Payable | $(52,120 | ) | ||||
| Accounts Receivable (net) | 51,200 | Bonds Payable | 84,090 | |||||
| Inventory | 134,200 | Common Stock | 127,800 | |||||
| Investments | (47,850 | ) | Paid-In Capital in Excess of Par—Common Stock | 15,390 | ||||
Compute the net income for the current year, assuming that there
were no entries in the Retained Earnings account except for net
income and a dividend declaration of $26,090 which was paid in the
current year.
In: Accounting
The following income statement and information about changes in
noncash current assets and current liabilities are
reported.
|
SONAD COMPANY Income Statement For Year Ended December 31, 2017 |
||||||
| Sales | $ | 2,117,000 | ||||
| Cost of goods sold | 1,037,330 | |||||
| Gross profit | 1,079,670 | |||||
| Operating expenses | ||||||
| Salaries expense | $ | 290,029 | ||||
| Depreciation expense | 50,808 | |||||
| Rent expense | 57,159 | |||||
| Amortization expenses–Patents | 6,351 | |||||
| Utilities expense | 23,287 | 427,634 | ||||
| 652,036 | ||||||
| Gain on sale of equipment | 8,468 | |||||
| Net income | $ | 660,504 | ||||
Changes in current asset and current liability accounts for the
year that relate to operations follow.
| Accounts receivable | $ | 33,500 | increase | Accounts payable | $ | 10,500 | decrease | |||
| Inventory | 39,625 | increase | Salaries payable | 5,700 | decrease | |||||
Prepare only the cash flows from operating activities section of the statement of cash flows using the indirect method.
Statement of Cash Flows (partial)
Cash flows from operating activities
Adjustments to reconcile net income to net cash provided by operating activities
Income statement items not affecting cash
Changes in current operating assets and liabilities
In: Accounting
Q1.
a. Dynamic changes in chromatin organization and the management
of individual linear chromosomes mark key
activities of the different stages of the eukaryotic cell cycle and
cellular reproduction. Describe how chromatin
amount and structure vary throughout the cell cycle, and how
management of individual chromosomes varies
between mitosis and meiosis to produce the different outcomes of
these processes.
b. RNA is often considered to be a more versatile macromolecule
than DNA. Discuss the different roles of RNA
in eukaryotes.
In: Biology
A businessman moves from Thailand to pursue a job opportunity in the US. His diet changes from one high in local raw fruits and vegetables to mainly canned and frozen vegetables. The fresh produce he does buy typically ships from overseas and since it doesn't taste good to him, he tends to avoid it. Over the course of his first year, the man experiences worsening fatigue, headaches, depression and gastrointestinal discomfort, despite taking mineral supplements and making sure to stay hydrated. After about a year he meets with a nutritionist who advises him to consume more raw produce from farmer's markets; this intervention does alleviate his symptoms.
Use your knowledge from this course and the information provided to address the following:
a) What specifically about the man's dietary change likely caused his initial symptoms and why was the nutritionist's recommendation effective?
b) Why do you think the nutritionist suggested he get his produce from local farmer's markets rather than a grocery store?
c) If the man were to move somewhere with little access to fruits and vegetables, what else could the nutritionist have suggested that would have been effective and why?
NOTE: For full credit you must apply your knowledge. Just restating the information provided is not sufficient. ie. saying "he changed his diet to eat raw vegetables" is just restating the information - explain, use your knowledge and provide your logic.
In: Biology
Epigenetics centres on inheritable phenotype changes that do not involve alterations in the DNA sequence, indicating the influence of environmental factors. Based on content covered in lectures, discuss the mechanisms implicated in the inheritance of epigenetic information.
In: Biology
Twelve men were placed on a weight-reducing diet. The changes in
weight (Kg) exhibited by the men were as follows. Determine whether
the diet is successful.
Data: -1.2, -1.4, -1.0, -0.4, -0.3, -0.8, 0.5, 0.1, -0.9, -1.8,
0.0, -2.1.
In: Statistics and Probability