True/False: There are usually less mutations near the transcription start site of the variable region for an antibody.

Which of the following is most analogous (or most closely matches) to the germinal center in the secondary lymphoid tissue?

a. the cortex of the thymus

b. the spongy tissue of the bone

c. the medulla of the thymus

d. the plasma of the bone marrow

Which of the following is not part of the T-cell receptor complex?

a. alpha chain

b. CD3 complex

c. beta chain

d. IgA

find the following critical t-scores

Near the beginning of the semester, you administered a survey to 10 students. Suppose we wanted to use your sample to calculate the mean age of college students. What are the critical t-scores for the mean age using your sample?

80% CI: t =

90% CI: t =

99% CI: t =

The Vintage Restaurant, on Captiva Island near Fort Myers, Florida, is owned and operated by Karen Payne. The restaurant just completed its third year of operation. During that time, Karen sought to establish a reputation for the restaurant as a high-quality dining establishment that specializes in fresh seafood. Through the efforts of Karen and her staff, her restaurant has become one of the best and fastest-growing restaurants on the island. To better plan for future growth of the restaurant, Karen needs to develop a system that will enable her to forecast food and beverage sales by month for up to one year in advance. Table below shows the value of food and beverage sales ($1,000s) for the first three years of operation:

Perform an analysis of the sales data for the Vintage Restaurant. Prepare a report for Karen that summarizes your findings, forecasts, and recommendations. Include the following:

1.A time series plot. Comment on the underlying pattern in the time series.

2.Using the dummy variable approach, forecast sales for January through December of the fourth year.

Assume that January sales for the fourth year turn out to be $295,000. What was your forecast error? If this error is large, Karen may be puzzled about the difference between your forecast and the actual sales value. What can you do to resolve her uncertainty in the forecasting procedure?

Hint: Run the first regression model with only the monthly dummy variables against Sales and the second regression model with Month number and monthly dummy variables against Sales. Compare the two models and select the best model for your forecast.

PLEASE SHOW YOUR CALCULATION AND FORMULAS!!!

At a playground you let your kid sister (30 kg) kneel on the surface (near the edge) of a 2 meter diameter merry-go-round, of mass 300 kg. You push the merry-go-round along the edge, so that it constantly accelerates from rest to a final speed of 1.5 rotations per second at the end of a 20 sec interval. Friction is negligible. b) How much force did you apply in the direction tangent to the circumference of the merry-go-round, at the point of contact (in Newtons), during the 20 sec time interval? c) After it comes up to speed, you stop pushing and the merry-go-round continues to run at a constant rate of 1.5 rotations per second (remember that we are neglecting friction). What is the magnitude and direction of your sister’s acceleration, if any? d) Your kid sister now walks across the center of the merry-go-round, to a point a distance 0.5 meters from the center “on the other side”. What is the new angular velocity of the merry-go-round (in rad/sec) when she is 0.5 meters from the center “on the other side”? e) For a rigid body undergoing rotation, write down a symbolic expression for its rotational kinetic energy, in terms of the magnitude of its angular momentum L, and its moment of inertia I about the rotation axis. f) What is the total change in the kinetic energy of the merry-go-round, including your sister, as a result of her walk (in Joules)? g) In the part of her walk from the center to the other side: (i) is the change in kinetic energy of the merry-go-round (including your sister) positive or negative? Explain. (ii) is the change in your sister’s kinetic energy positive or negative? Explain.

Brookdale Hospital hired an inexperienced controller early in 20X4. Near the end of 20X4, the board of directors decided to conduct a major fund-raising campaign. They wished to have the December 31, 20X4, statement of financial position for Brookdale fully conform with current generally accepted principles for hospitals. The trial balance prepared by the controller at December 31, 20X4, follows:

Your analysis of the contribution’s receivable as of December 31, 20X4, determined that there were unrecognized contributions for the following:

Unrestricted use$40,300 Cancer research 10,800 Purchase of equipment 20,500 Permanently restricted endowment principal 32,000 Total$103,600

2. Short-term investments at year-end consist of $151,600 of funds without donor restrictions and $50,000 of funds restricted for future cancer research. All of the long-term investments are held in the permanently restricted endowment fund.
3. Land is carried at its current market value of $121,600. The original owner purchased the land for $70,500, and at the time of donation to the hospital, it had an appraised value of $97,000.
4. Buildings purchased 11 years ago for $610,500 had an estimated useful life of 30 years. Equipment costing $152,400 was purchased 7 years ago and had an expected life of 10 years. The controller had improperly increased the reported values of the buildings and equipment to their current fair value of $935,700 and had incorrectly computed the accumulated depreciation.
5. The board of directors voted on December 29, 20X4, to designate $101,700 of funds without donor restrictions invested in short-term investments for developing a drug rehabilitation center.

Answer is not complete.

Consider the following information available in Diamond Bank located in a neighborhood near you.

         Spot Rate for the British Pound Sterling                                                                 $1.60

         90 – day forward rate of the pound                                                                         $1.59

         90 – day UK interest rate                                                                                               4%

         90 – day U.S. interest rate                                                                                             3%

(a)Given this information, would it be a prudent strategy for Diamond Bank to engage in covered interest arbitrage? Explain.

(b)If covered interest arbitrage is profitable how much profit would the Bank earn if it uses $1,000,000?

(c)Briefly discuss the realignment process that will yield interest rate parity.

Phil Nelson, 19 year old, was brought to the ER following a near-drowning. He was not breathing when the paramedics pulled him out of the lake. CPR was given and he awoke. Upon arrival to the ER, he was extremely anxious with a BP of 118/62 and respiratory rate of 26. He was alert and oriented X 3 and the nurse auscultated crackles along with expiratory wheezing throughout all lung fields. A 40% face mask was applied and his ABGs were:

pH 7.48          PaCO₂   28      PaO₂ 48          O₂sat 90%      HCO₃   24. All other labs were normal.

Interpretation of this ABG __________________________________________________

Phil remained stable for the next 24 hours but became dyspneic, tachypneic, tachycardic and developed progressive hypoxemia. Despite the ICU nurse increasing the FIO₂, his ABGs continued to deteriorate. On 100% nonrebreather mask, his ABGs were:

pH 7.50          PaCO₂   28      PaO₂ 48          O₂sat 77%      HCO₃   24

Interpretation of this ABG __________________________________________________

He was intubated and ventilated with the following settings:            AC 12, FIO₂ 60%, TV 800ml, and PEEP of 5. Post intubation X-ray showing proper ET placement but bilateral diffuse, patchy infiltrates were noted. A pulmonary artery catheter was inserted and the following readings were obtained:

PA 25/10                   pH 7.48

PAWP 8                     PCO₂ 30

CVP 6                        PaO₂ 58

CO 7.5                        O₂ sat 89%

                                    HCO₃ 24

Interpretation of this ABG __________________________________________________

Phil Nelson was diagnosed with ARDS.

1.     What is ARDS? What is the diagnostic criterion for ARDS?

2.     What clinical conditions are commonly associated with ARDS?

3.     What are the major pathophysiologic alterations in ARDS?

4.     What are the clinical signs and symptoms of ARDS?

5.     What is the usual cause of hypoxemia in ARDS?

6.     What is the treatment for an intrapulmonary shunt?

7.     How can PEEP affect O₂ transport?

Phil Nelson’s ABGs were not improving as expected. The physician ordered a PEEP of 10. Thirty minutes later another set of ABGs were drawn but the PaCO₂ remained 32 and the PaO₂ only increased to 65. The physician increased the PEEP to 15 and the PaO₂ increased to 88 and the O₂ sat increased to 95%. However, the nurse performed a cardiac output which was reported as 3.8. Why?

8.     The physician was hesitant to increase the FIO₂ further than 60%. What was the physician concerned about?

9.     Phil was restless and the nurse notes that he is “bucking” the vent. Why is this a concern? What should the nurse assess for?

Despite the typical medical/nursing interventions, the client has not improved, and the physician orders a neuromuscular blockade. What is this therapy and why is it used?

10. What are the most essential nursing responsibilities when caring for a mechanically ventilated client receiving neuromuscular blockade?

11. Morphine was prescribed to Phil’s drug regimen. Why? What other medications do you anticipate the physician ordering for a patient who is on neuromuscular blockade?

12. Phil’s BP drops to 90/58 and his CVP to 2, and his PAWP to 4. Urine output is less than 30ml/hr. What therapy do you anticipate?

13. Phil is started on enteral feedings. Why is nutrition important in the patient with ARDS?

14. What is the leading cause of death in patients with ARDS?

15. Identify and prioritize three of the most important nursing diagnoses that are appropriate in caring for Phil.

Lavage Rapide is a Canadian company that owns and operates a large automatic carwash facility near Montreal. The following table provides data concerning the company’s costs:

For example, electricity costs are $1,100 per month plus $0.06 per car washed. The company expects to wash 8,400 cars in August and to collect an average of $6.80 per car washed.

The actual operating results for August appear below.

Required:

Complete the flexible budget performance report that shows the company’s activity variances and revenue and spending variances for August. (Indicate the effect of each variance by selecting "F" for favorable, "U" for unfavorable, and "None" for no effect (i.e., zero variance). Input all amounts as positive values.)

Lavage Rapide is a Canadian company that owns and operates a large automatic carwash facility near Montreal. The following table provides data concerning the company’s costs:

For example, electricity costs are $1,100 per month plus $0.06 per car washed. The company expects to wash 8,400 cars in August and to collect an average of $6.80 per car washed.

The actual operating results for August appear below.

Required:

Complete the flexible budget performance report that shows the company’s activity variances and revenue and spending variances for August. (Indicate the effect of each variance by selecting "F" for favorable, "U" for unfavorable, and "None" for no effect (i.e., zero variance). Input all amounts as positive values.)

It is​ April, and Hans Anderson is planting his barley crop near​ Plunkett, Saskatchewan. He is concerned about losing his farm if his operations result in a loss at the end of the season. He expects to harvest 3 comma 000 tonnes of barley and sell it in October. Futures contracts are available for October delivery with a futures price of $ 200 per tonne. Options with strike price of $ 200 per tonne are also​ available; puts cost $ 16 and calls cost $ 20. a. Describe how Hans can fully hedge using futures contracts. b. Given the strategy in ​(a​), what will be the total net amount received by Hans​ (for all 3 comma 000 ​tonnes) if the price of barley in October is as​ follows: i . $ 150 per​ tonne; ii. $ 200 per​ tonne; iii. $ 250 per tonne c. Describe how Hans can fully hedge using options. d. Given the strategy in ​(c​), what will be the total net amount received by Hans​ (for all​ 3,000 tonnes) if the price of barley in October is as​ follows: i. $ 150 per​ tonne; ii. $ 200 per​ tonne; iii. $ 250 per tonne e. Hans has asked for your advice regarding hedging. Discuss how the each of the following individually will influence your advice. i. Hans does not expect to have much cash available between May and September. ii. Hans thinks there is a 25​% chance his crop will be destroyed by hail before he has a chance to harvest it. iii.​ Hans's farming business will go bankrupt if his net revenues in October do not cover his costs. He estimates his costs will be $ 570 comma 000. If his business goes​ bankrupt, Hans's bank will foreclose and take his house and farm. iv.​ Hans's farming business will go bankrupt if his net revenues in October do not cover his costs. He estimates his costs will be $ 800 comma 000. If his business goes​ bankrupt, Hans's bank will foreclose and take his house and farm.