1.   A physician orders 2000 units of heparin to be administered by intravenous infusion per hour. The pharmacy provides a heparin IV bag containing 25,000 units of heparin in 250 ml of D5W.  How many ml should be administered per minutes?

2.A male patient weighing 85 kg is placed on heparin therapy for the prevention of deep vein thrombosis after surgery. How many ml of a heparin injection containing 5000 units/ml should be administered for a loading dose of 75 units/kg?

3.  Following the question 2, what should be the infusion rate in ml/hr, using a solution that contains heparin 25000 units/500 ml, to administer 18 units/kg/hr?

Consider the following data:

Number of Deaths in the U.S. by Drug Overdose

Year 2000 2001 2002 2003 2004 2005 2006 2007 2008

Deaths 17,054 17,514 14,315 13,332 17,775 14,556 11,151 18,650 16,647

Step 1 of 2 : Find the two-period moving average for the year 2003. If necessary, round your answer to one decimal place.

3. From 2000-2019 there were a total of 3071 earthquakes worldwide with a magnitude of 6 or greater, or an average of about 0.42 such earthquakes per day.* Assume that moving forward the total number of such earthquakes to occur over any time period follows a Poisson distribution with an average of 0.42 earthquakes per day. For the remainder of this question, “earthquake” will mean an earthquake with a magnitude of 6 or greater. Define a new random variable as necessary in each part of this question.

(a) What is the probability that there are no earthquakes during a single day?

(b) What is the probability that there are at least three earthquakes during a single week?

FUN FACT: When the number of events over any time interval follow a Poisson distribution, the time between any two events follows an exponential distribution with a mean equal to the reciprocal of the mean for the Poisson distribution. Therefore the time between two earthquakes follows an exponential distribution with an average of about 2.38 days. Answer the following three questions using the exponential distribution.

(c) What is the probability that the time between two earthquakes will be less than three days?

(d) If an earthquake just occurred, what is the probability that the time until the next earthquake will be more than 12 hours but less than 24 hours? (e) What is the median time between two earthquakes?

*https://www.usgs.gov/natural-hazards/earthquake-hazards/lists-maps-and-statistics

Mr J Ockey commenced trading as a wholesaler stationer on 1 May 2000 with a capital of £5,000.00 with which he opened a bank account for his business. During May the following transactions took place.

May 1 Bought shop fittings and fixtures from store fitments Ltd for £2,000.00

May 2 Purchased goods on credit from Abel £650.00

May 4 Sold goods on credit to Bruce £700.00

May 9 Purchased goods on credit from Green £300.00

May 11 Sold goods on credit to Hill £580.00

May 13 Cash sales paid into bank account £200.00

May 16 Received cheque from Bruce in settlement of his account

May 17 Purchased goods on credit from Kay £800.00

May 18 Sold goods on credit to Nailor £360.00

May 19 Sent Cheque to Abel in settlement of his account

May 20 Paid rent by cheque £200.00

May 21 Paid delivery expenses by cheque £50.00

May 24 Received from Hill £200.00 on account

May 30 Drew cheque for personal expenses £200.00 and assistant wages £320.00

May 31 Settled the account of Green.

Required

a) Record the transactions in the books of prime entry.

b) Post the entries in the ledger accounts

c) Balance the ledger accounts where necessary

d) Extract a trial balance as at 31 May 2000.

This is a summary from Physics World of the paper: L J Wang et al. 2000 Nature 406 277-- "Wang and colleagues begin by using a third continuous-wave laser to confirm that there are two peaks in the gain spectrum and that the refractive index does indeed change rapidly with wavelength in between. Next they send a 3.7-microsecond long laser pulse into the caesium cell, which is 6 centimetres long, and show that, at the correct wavelength, it emerges from the cell 62 nanoseconds sooner than would be expected if it had travelled at the speed of light. 62 nanoseconds might not sound like much, but since it should only take 0.2 nanoseconds for the pulse to pass through the cell, this means that the pulse has been travelling at 310 times the speed of light. Moreover, unlike previous superluminal experiments, the input and output pulse shapes are essentially the same."

I realise that the velocity of light in a medium is comprised of the phase velocity, the group velocity, and the front velocity. While the group velocity can exceed the value of c in a vacuum, the front velocity is not supposed to. The way this sounds, the front velocity is exceeding c in a vacuum by 310 times.
blue dot=phase velocity, green=group, red=front (wiki)

The wavepacket seems to exit the cell well before it enters, but the negative refractive index "forward shifts" the leading edge of the pulse. It is argued that although this is superluminal, information cannot be transmitted faster than c. Gauthier and Stenner introduced a jump discontinuity into the waveform.Its max speed was c Here is a popular account from NewScientist . What if you used one photon? What if the photon itself were the information and not a carrier?

Cigar smoking and cancer. The Journal of the National Cancer Institute (Feb. 16, 2000) published the results of a study that investigated the association between cigar smoking and death from tobacco-related cancers. Data were obtained for a national sample of 137,243 American men. The results are summarized in the table below. Each male in the study was classified according to his cigar-smoking status and whether or not he died from a tobacco-related cancer.

Find the Odds Ratio for Dying versus Not Dying from Cancer for a Current Smoker compared with a Never Smoker. Hint, you must do the odds for each group first. The current smoker is the numerator for the odds ratio. Use 4 significant decimal places for your answer, and use the proper rules of rounding. I am looking for just the answer, not the equation.

A process to produce 2000 ton/ year of pyruvic acid requires a total capital investment of $ 30 million (working capital of $ 3 million). Fixed operating costs are $ 1 million/ year and the the variable operating costs (excluding raw materials) is expected to be $ 0.5/kg product. The yield of the product per ton of raw material is 80%. The tax rate is 35%. Calculate the selling price (in $/kg) which gives a minimum ROI after tax of 35%. Assume straight line depreciation. The project life is 10 years.

On 31 December 2000, Columbia Inc. entered into an agreement with Scotia Ltd. to lease equipment with a useful life of 6 years. Columbia Inc. will make four equal payments of $134,000 at the beginning of each lease year. Columbia Inc. anticipates that the equipment will have a residual value of $91,200 at the end of the lease, net of removal costs. Columbia Inc. has the option of extending the lease by (1) paying $91,200 to retain the equipment or (2) allowing Scotia Ltd. to remove it. Scotia Ltd.’s implicit interest rate in this lease is 8%. Columbia Inc.’s incremental borrowing rate is 9%. Columbia Inc. depreciates the leased equipment on a straight-line basis. The lease commences on 1 January 2001. Assume that the fair value of the equipment on the open market is greater than the present value of the lease payments. (PV of $1, PVA of $1, and PVAD of $1.) (Use appropriate factor(s) from the tables provided.)

Required:

1. Prepare a lease liability amortization table for this lease for Columbia Inc. (Round your final answers to the nearest whole dollar amount. Leave no cell blank. Be certain to enter "0" wherever required.)

2. Prepare all entries that Columbia Inc. will record for this lease for 2011 and 2012. (Round your intermediate calculations and final answers to the nearest whole dollar amount. If no entry is required for a transaction/event, select "No journal entry required" in the first account field.)

The following table consists of one student athlete's time (in minutes) to swim 2000 yards and the student's heart rate (beats per minute) after swimming on a random sample of 10 days.

For computation purposes,
?¯x¯ = 34.998 , ?¯y¯ = 140.8 , ∑?∑x= 349.98 , ∑?∑y = 1408 , ∑??∑xy = 49295.03 , ∑?2∑x2 = 12252.1068 , ∑?2∑y2 = 199442 ,
Use swim time as the explanatory variable ?x and compute the correlation coefficient, then find the least-squares regression line.

The correlation coefficient is ?=r=  . (Round to 4 decimal places.)

The equation of the least squares line is
?̂ =y^=  +  x. (Round to 4 decimal places.)

1. In October 2000, the U.S. Department of Commerce reported the results of a large-scale survey on high school graduation. Researchers contacted more than 25,000 Americans aged 24 years to see if they had finished high school; 83.9% of the 12,460 males and 87.8% of the 12,678 females indicated that they had high school diplomas.

a. Are the assumptions and conditions necessary for inference satisfied? Explain.

b. Create a 95% confidence interval for the difference in graduation rates between males and females.

c. Interpret your confidence interval.

d. Does this provide strong evidence that girls are more likely than boys to complete high school? Explain.