In a study of monthly salary distribution of residents in Paris conducted in year 2015, it was found that the salaries had an average of €2200 (EURO) and a standard deviation of €550. Assume that the salaries were normally distributed.

In 2017, a study on the salary distribution of Paris residents was conducted. Assume that the salaries were normally distributed. A random sample of 10 salaries was selected and the data are listed below:

Question 1: Assume that the standard deviation of the salaries was still the same as in 2015. Estimate the average salary (in 2017) with 95% confidence.

Question 2: The assumption made in Question 8 was certainly unrealistic. Estimate the average salary (in 2017) with 95% confidence again assuming that the standard deviation had changed from 2015.

Question 3: Estimate the variance of monthly salaries of Paris residents (in 2017) based on the sample provided above at a 95% confidence level.

A similar study was conducted on salary distribution of Paris residents in 2019. The research team aimed to estimate the average salary. They chose the 98% confidence and assumed that the population standard deviation was the same as in 2015. Assume again that those salaries were normally distributed.

Question 4 :If they would like the (margin of) error to be no more than €60, how large a sample would they need to select? (That is, find the minimum sample size.)

Select one:

A: 322

B: 323

C: 456

D: 457

The maximum reaction rates (Vmax) for the enzyme invertase were measured from samples at four temperatures. Test the hypothesis that there are no significant differences in the mean invertase reaction rates among temperatures at the 5% level of significance. (8 points)

7. Report the SS(total) value

a. 4.0500

b.5.5800

c.2.5300

d. 4.1094

8. Report the SS(error) value

a.2.0922

b.2.4950

c.3.4400

d.4.5430

9. Report the MS(group) value

a.0.3592

b.0.5382

c.0.2582

d.0.6526

10. Report the MS(error) value

a.0.3928

b.0.5322

c.0.2078

d.0.1744

11. What is the F-ratio?

a. 2.59

b.3.74

c.4.83

d.5.46

12.What is the F(critical) value?

a.2.97

b.3.49

c.4.83

d.5.46

13. Which of the following Null Hypothesis is true?

a.H0: All sites have equal means

b.H0: Two of the sites have equal means

c. H0:At least one site has a different mean

d. H0: Two sites do NOT have equal means

14. Which of the following Alternate Hypothesis is true?

a.H1:All sites have equal means

b.H1:Two of the sites have equal means

c.H1:At least one site has a different mean

d.H1:Two of the sites do NOT have equal means

15. What is your conclusion?

a.Reject H0

b.Do Not Reject H0

c. All sites have different means

Which enzyme or complex shortens the length of BOTH siRNA and miRNA?
a) Dicer
b) Slicer/Argonaute
c) RISC
d) RNase III
e) both a and b

siRNA introduced into a cell is amplified by the action of _____.
a) Dicer
b) Drosha
c) a DNA-dependent DNA polymerase
d) an RNA-dependent DNA polymerase
e) an RNA-dependent RNA polymerase

What is the correct order of steps in generation of a functional miRNA?
a) RISC binding RNA, processing in the nucleus, processing in the cytosol.
b) RISC binding RNA, processing in the cytosol, processing in the nucleus.
c) Processing in the nucleus, processing in the cytosol, incorporation into RISC.
d) Processing in the cytosol, processing in the nucleus, incorporation into RISC.
e) Processing in the nucleus, incorporation into RICS binding, processing in the cytosol.

The maximum reaction rates (Vmax) for the enzyme invertase were measured from samples at four temperatures. Test the hypothesis that there are no significant differences in the mean invertase reaction rates among temperatures at the 5% level of significance. (8 points)

1. What type of Analysis should you conduct to solve this problem? a. Two-Factor ANOVA b. One-Factor ANOVA c. Paired t-test d. Independent t-test

2. What are the sample sizes for each group? (n1, n2, n3, n4) a. 5, 4, 3, 4 b. 5, 8, 12, 8 c. 4, 5, 3, 4 d. 5, 4, 4, 3

3. What is the total sample size? a. 4 b. 5 c. 16 d. 12

4. What is the total average? a. 2.9840 b. 2.7640 c. 2.9063 d. 2.6500

5. What is the total Sum of all observations? a. 46.5 b. 34.0 c. 54.6 d. 45.2

6. Report the SS(group) value. a. 1.0778 b. 1.9578 c. 3.9520

Q1: hydrolysis of an ester using a Lipase CALB enzyme.

1. Use an organic chemistry textbook to draw the mechanism of hydrolysis of the corresponding non enzymatic reaction- ester hydrolysis using acid/base catalysis. Enzymatic reactions often involve general acid or general base catalysis rather than such specific acid or specific base catalysis. explain what this means.

3. With as much detail as you can identify the catalytic residues involved in each step, and discuss their involvement in the catalytic mechanism for each of the steps involved (acid, base, covalent catalysis). Propose how the starting material and tetrahedral intermediates/transition states could be bound via non-covalent interactions to other residues at the active site and hence any influence from them.

Learning Task 12-01

The Enzyme Lactase Experiment Design

Check off the items in this list that you would use for this experiment. You may add any items you feel you would need.

Describe what you would do in your experiment. For each step, explain why the step is important. Add more steps if required.

If you actually conducted this experiment, what safety issues would you need to identify?

If you actually conducted this experiment, what appropriate precautions would you take to ensure that you performed the experiment safely?

If you actually conducted this experiment, what results would you expect to see?

Why would you expect these results?

The enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.

The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9 mol/l). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7 mol/l).

Compute the total concentration of [D1]tot that is needed to bind 90% of the HIV-RT at the given concentration [E]tot.You do NOT have to consider competition betwwen the drugs D1 and D2! They are administered separately.

Compute the total concentration of [D2]tot that is needed to bind 90% of the HIV-RT at the given concentration [E]tot. You do NOT have to consider competition between the drugs D1 and D2! They are administered separately.

5. Lipids are chemically digested only by the enzyme lipase.

Group of answer choices

True

False

36. Lipid absorption into the epithelial cells of villi occurs via active transport.

Group of answer choices

True

False

37. Triglycerides are resynthesized inside the epithelial cells of the villus
before they enter the central lacteal of the villus.

Group of answer choices

True

False

38. Chylomicrons move from small intestine to the liver through the
hepatic portal system.

Group of answer choices

True

False

39. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

There would be an increase in aldosterone secretion

Group of answer choices

True

False

40. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

Sodium reabsorption in the kidney tubules would increase

Group of answer choices

True

False

41. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

Peripheral vasodilation would occur.

Group of answer choices

True

False

42. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

Water reabsorption decreases.

Group of answer choices

True

False

Write a class (and a client class to test it) that encapsulates a tic-tac-toe board. A tic-tac-toe board looks like a table of three rows and three columns partially or completely filled with the characters X and O. At any point, a cell of that table could be empty or could contain an X or an O. You should have one instance variable, a two-dimensional array of values representing the tic-tac-toe board.

This game should involve one human player vs. the computer. At the start of each game, randomly select if the computer will play X or O and who (i.e. human or computer) will make the first move.

Your default constructor should instantiate the array so that it represents an empty board.

You should include the following methods:

*a method that generates a valid play by the computer and displays the board after each play. *

a method that requests a valid play from the human and displays the board after each play.

*a method to display the tic-tac-toe board. a method checking if a player has won based on the contents of the board; this method takes no parameter. It returns X if the "X player" has won, O if the "O player" has won, T if the game was a tie. A player wins if he or she has placed an X (or an O) in all cells in a row, all cells in a column, or all cells in one of the diagonals.

NOTE: Be sure to display the board after each move. You must provide clear prompts for the human player to select a space on the tic-tac-toe board.

Input Validation: Verify that all moves by the human player are to a valid space on the tic-tac-toe board. An incorrect choice should not halt or terminate the game.

What types of research projects can you think of Cognitive Science?

For example, an example of a very famous research project is Dr. Rosalind Picard's Affective computing and autism project. Can you think of 5 research projects that are Cognitive Science and Artificial Intelligence/Machine Learning research projects? Please include the name of the professor and the name of the university where the research project is being conducted.

Cognitive Science:

Studying in scientific way about human thoughts, learning and mental organization.

What types of research projects can you think of Cognitive Science?

Research projects which explains human thoughts, learning and mental organization in deep and scientific way.

5 research projects:

This is the type of example I am looking for: Automated ‘coach’ could help with social interactions

New software system from MIT could help people improve their conversational and interview skills.

Teaching Social Skills: Using his expertise in computer science, machine learning, and artificial intelligence, Ehsan Hoque, assistant professor of computer science, has since created an automated conversation assistant that senses body language and emotion.

The biggest problem with this example is that sometimes there is very little info on these projects.