Ecru Company has identified five industry segments: plastics, metals, lumber, paper, and finance.

It appropriately consolidated each of these segments in producing its annual financial statements. Information describing each segment (in thousands) follows:

Ecru does not allocate its $1,390,000 in common expenses to the various segments.

Perform testing procedures to determine Ecru’s reportable operating segments.

A. Revenue Test

B. Profit of loss test:

C. Asset test

Consider the following data for 15 subjects with two predictors. The dependent variable, MARK, is the total score for a subject on an examination. The first predictor, COMP, is the score for the subject on a so-called compulsory paper. The other predictor, CERTIF, is the score for the subject on a previous exam.

a.Run a stepwise regression on the dataset

b.Does CERTIF add anything to predicting MARK, above and beyond that of COMP?

c. Write out the prediction equation

d. A statistician wishes to know the sample size needed in a multiple regression study. She has four predictors and can tolerate at most a .10 drop-off in predictive power. But she wants this to be the case with .95 probability. From previous related research, the estimated squared population multiple correlation is .62. How many subjects are needed?

In a study of monthly salary distribution of residents in Paris conducted in year 2015, it was found that the salaries had an average of €2200 (EURO) and a standard deviation of €550. Assume that the salaries were normally distributed.

In 2017, a study on the salary distribution of Paris residents was conducted. Assume that the salaries were normally distributed. A random sample of 10 salaries was selected and the data are listed below:

Question 1: Assume that the standard deviation of the salaries was still the same as in 2015. Estimate the average salary (in 2017) with 95% confidence.

Question 2: The assumption made in Question 8 was certainly unrealistic. Estimate the average salary (in 2017) with 95% confidence again assuming that the standard deviation had changed from 2015.

Question 3: Estimate the variance of monthly salaries of Paris residents (in 2017) based on the sample provided above at a 95% confidence level.

A similar study was conducted on salary distribution of Paris residents in 2019. The research team aimed to estimate the average salary. They chose the 98% confidence and assumed that the population standard deviation was the same as in 2015. Assume again that those salaries were normally distributed.

Question 4 :If they would like the (margin of) error to be no more than €60, how large a sample would they need to select? (That is, find the minimum sample size.)

Select one:

A: 322

B: 323

C: 456

D: 457

The maximum reaction rates (Vmax) for the enzyme invertase were measured from samples at four temperatures. Test the hypothesis that there are no significant differences in the mean invertase reaction rates among temperatures at the 5% level of significance. (8 points)

7. Report the SS(total) value

a. 4.0500

b.5.5800

c.2.5300

d. 4.1094

8. Report the SS(error) value

a.2.0922

b.2.4950

c.3.4400

d.4.5430

9. Report the MS(group) value

a.0.3592

b.0.5382

c.0.2582

d.0.6526

10. Report the MS(error) value

a.0.3928

b.0.5322

c.0.2078

d.0.1744

11. What is the F-ratio?

a. 2.59

b.3.74

c.4.83

d.5.46

12.What is the F(critical) value?

a.2.97

b.3.49

c.4.83

d.5.46

13. Which of the following Null Hypothesis is true?

a.H0: All sites have equal means

b.H0: Two of the sites have equal means

c. H0:At least one site has a different mean

d. H0: Two sites do NOT have equal means

14. Which of the following Alternate Hypothesis is true?

a.H1:All sites have equal means

b.H1:Two of the sites have equal means

c.H1:At least one site has a different mean

d.H1:Two of the sites do NOT have equal means

15. What is your conclusion?

a.Reject H0

b.Do Not Reject H0

c. All sites have different means

Which enzyme or complex shortens the length of BOTH siRNA and miRNA?
a) Dicer
b) Slicer/Argonaute
c) RISC
d) RNase III
e) both a and b

siRNA introduced into a cell is amplified by the action of _____.
a) Dicer
b) Drosha
c) a DNA-dependent DNA polymerase
d) an RNA-dependent DNA polymerase
e) an RNA-dependent RNA polymerase

What is the correct order of steps in generation of a functional miRNA?
a) RISC binding RNA, processing in the nucleus, processing in the cytosol.
b) RISC binding RNA, processing in the cytosol, processing in the nucleus.
c) Processing in the nucleus, processing in the cytosol, incorporation into RISC.
d) Processing in the cytosol, processing in the nucleus, incorporation into RISC.
e) Processing in the nucleus, incorporation into RICS binding, processing in the cytosol.

The maximum reaction rates (Vmax) for the enzyme invertase were measured from samples at four temperatures. Test the hypothesis that there are no significant differences in the mean invertase reaction rates among temperatures at the 5% level of significance. (8 points)

1. What type of Analysis should you conduct to solve this problem? a. Two-Factor ANOVA b. One-Factor ANOVA c. Paired t-test d. Independent t-test

2. What are the sample sizes for each group? (n1, n2, n3, n4) a. 5, 4, 3, 4 b. 5, 8, 12, 8 c. 4, 5, 3, 4 d. 5, 4, 4, 3

3. What is the total sample size? a. 4 b. 5 c. 16 d. 12

4. What is the total average? a. 2.9840 b. 2.7640 c. 2.9063 d. 2.6500

5. What is the total Sum of all observations? a. 46.5 b. 34.0 c. 54.6 d. 45.2

6. Report the SS(group) value. a. 1.0778 b. 1.9578 c. 3.9520

Q1: hydrolysis of an ester using a Lipase CALB enzyme.

1. Use an organic chemistry textbook to draw the mechanism of hydrolysis of the corresponding non enzymatic reaction- ester hydrolysis using acid/base catalysis. Enzymatic reactions often involve general acid or general base catalysis rather than such specific acid or specific base catalysis. explain what this means.

3. With as much detail as you can identify the catalytic residues involved in each step, and discuss their involvement in the catalytic mechanism for each of the steps involved (acid, base, covalent catalysis). Propose how the starting material and tetrahedral intermediates/transition states could be bound via non-covalent interactions to other residues at the active site and hence any influence from them.

Learning Task 12-01

The Enzyme Lactase Experiment Design

Check off the items in this list that you would use for this experiment. You may add any items you feel you would need.

Describe what you would do in your experiment. For each step, explain why the step is important. Add more steps if required.

If you actually conducted this experiment, what safety issues would you need to identify?

If you actually conducted this experiment, what appropriate precautions would you take to ensure that you performed the experiment safely?

If you actually conducted this experiment, what results would you expect to see?

Why would you expect these results?

The enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.

The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9 mol/l). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7 mol/l).

Compute the total concentration of [D1]tot that is needed to bind 90% of the HIV-RT at the given concentration [E]tot.You do NOT have to consider competition betwwen the drugs D1 and D2! They are administered separately.

Compute the total concentration of [D2]tot that is needed to bind 90% of the HIV-RT at the given concentration [E]tot. You do NOT have to consider competition between the drugs D1 and D2! They are administered separately.

5. Lipids are chemically digested only by the enzyme lipase.

Group of answer choices

True

False

36. Lipid absorption into the epithelial cells of villi occurs via active transport.

Group of answer choices

True

False

37. Triglycerides are resynthesized inside the epithelial cells of the villus
before they enter the central lacteal of the villus.

Group of answer choices

True

False

38. Chylomicrons move from small intestine to the liver through the
hepatic portal system.

Group of answer choices

True

False

39. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

There would be an increase in aldosterone secretion

Group of answer choices

True

False

40. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

Sodium reabsorption in the kidney tubules would increase

Group of answer choices

True

False

41. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

Peripheral vasodilation would occur.

Group of answer choices

True

False

42. If a person loses blood, renin release from the kidney increases. This in turn increases the levels of angiotensin II. Which of the following effects would occur due to these increases in renin and angiotensin II?

Water reabsorption decreases.

Group of answer choices

True

False