In each problem show all steps of the hypothesis test. If some of the assumptions are not met, note that the results of the test may not be correct and then continue the process of the hypothesis test.

1. The Kyoto Protocol was signed in 1997, and required countries to start reducing their carbon emissions. The protocol became enforceable in February 2005. In 2004, the mean CO2 emission was 4.87 metric tons per capita. Table 7.3.3 contains a random sample of CO2 emissions in 2010 ("CO2 emissions," 2013). Is there enough evidence to show that the mean CO2 emission is lower in 2010 than in 2004? Test at the 1% level. Table #7.3.3: CO2 Emissions (in metric tons per capita) in 2010 (1.36 1.42 5.93 5.36 0.06 9.11 7.32 7.93 6.72 0.78 1.80 0.20 2.27 0.28 5.86 3.46 1.46 0.14 2.62 0.79 7.48 0.86 7.84 2.87 2.45)

2. Table #7.3.7 contains pulse rates after running for 1 minute, collected from females who drink alcohol ("Pulse rates before," 2013). The mean pulse rate after running for 1 minute of females who do not drink is 97 beats per minute. Do the data show that the mean pulse rate of females who do drink alcohol is higher than the mean pulse rate of females who do not drink? Test at the 5% level. Table #7.3.7: Pulse Rates of Woman Who Use Alcohol (176 150 150 115 129 160 120 125 89 132 120 120 68 87 88 72 77 84 92 80 60 67 59 64 88 74 68)

3. Maintaining your balance may get harder as you grow older. A study was conducted to see how steady the elderly is on their feet. They had the subjects stand on a force platform and have them react to a noise. The force platform then measured how much they swayed forward and backward, and the data is in table #7.3.10 ("Maintaining balance while," 2013). Do the data show that the elderly sway more than the mean forward sway of younger people, which is 18.125 mm? Test at the 5% level. Table #7.3.10: Forward/backward Sway (in mm) of Elderly Subjects (19 30 20 19 29 25 21 24 50)

1) Pat gave 5,000 shares of stock in Coyote Corporation (a publicly traded corporation) to her church (a qualified charitable organization) in the current year. The stock was worth $180,000 and she had acquired it as an investment four years ago at a cost of $120,000. She reported AGI of $300,000 for the year. In completing her current income tax return, how much is her current-year charitable contribution deduction?

2)

Brad, who would otherwise qualify as Faye’s dependent, had gross income of $9,000 during the

year. Faye, who had AGI of $120,000, paid the following medical expenses this year:

What is the total medical expense deduction for Faye?

3)

Corey is the city sales manager for “RIBS,” a national fast food franchise. Every working day,

Corey drives his car as follows:

Corey renders an adequate accounting to his employer. What are Corey’s reimbursable miles?

Bob and Cathy, husband and wife, both age 40, have the following transactions during 2019:

-They sold their old residence on January 28, 2019 for $380,000. The basis of the their old residence, purchased in 2008, was $70,000. The selling expenses were $20,000. On May 17, 2018 they purchased and moved into another residence costing $150,000.

-On April 28, 2019, they sold for $8,000 stock that Cathy had received as a gift from her mother, who had purchased the stock for $10,000 in 2013. Her mother gave Cathy the stock on November 15, 2017 when the fair market value was $9,400.

-On May 24, 2019, Bob sold for $21,000 stock inherited from his father. His father died on June 14, 2017, when the fair market value of the stock was $9,000. Bob’s father paid $7,000 for the stock in 2011.

-On August 11, 2019, they sold a personal automobile for $8,000; basis of the automobile was $20,000 and it was purchased in 2015.

Bob had a salary of $40,000 and Cathy had salary of $28,000. They have no children. They paid state income taxes of $6,200, sales tax of $400, federal income taxes of $15,000, and property taxes of $1,700. In addition, they contributed $16,000 to their church and paid $4,000 interest on their mortgage.

Compute Bob and Cathy’s taxable income for 2019.

Comprehensive Problem (TAX RETURN PROBLEM)

Barry and Connie, Husband and wife, are both age 24, and have two sons. Barry earned $51,000 and Connie earned $45,000 during 2020. They both paid $4,200 state income taxes, $12,000 federal income taxes, $5,500 property taxes, $14,600 to First Presbyterian Church, $600 to needy families, $6,400 interest on their mortgage, and $6,800 medical expenses. In addition, they had the following transaction:

a) They sold their personal residence for $170,000. Their basis in the residence was $104,000. They incurred $7,000 in selling expenses. They purchases a new residence six months later for $220,000.

b) Connie sold for $40,000 property she had inherited from her father in 2015. Her father's basis in the property was $15,000 and the fair market value on the date of death was $30,000.

c) They sold for $6,000 business property which they had acquired as a gift in 2017. The basis to the donor was $7,500 and the fair market value on the date of the gift was $7,000.

d) they exchanged 100 shares of Conway Corp. common stock, with a basis of $3,000, for 75 shares of Conway Corp. nonvoting common stock with a fair market value of 10,0000.

Determine Barry and Connie's lowest taxable income. Treat all income as ordinary income.

5. Urokinase and chymotrypsin ( a digestive enzymes) have one domain in common with each other. This suggests that

a. they eveolve through exon shuffling

b. they are part of a gene family

c. they perform similar functions

9. which of the following point mutations would have little or no effect on cellular function?

a. mutation from AUA to AUG

b. mutation in regulatory region

c. mutation from CUC to AUU

d. mutation from UUA to UUG

e. mutation in exon

f. mutation in introns

10. scientists have estimated mutation rates by studying mutatant E.coli that are His-. Which of the following is (are) NOT true about the experiment involving His- E. coli?

a. His- mutants requires histidine in the media

b.His- mutants can not tolerate histidine

c. His- mutants spontaneously revert back to His+

d. His- mutants can not digest histidine

11. The National Toxicology Program report in 2016 that cell phone radiation increased brain tumor growth in male rats. Radiation can cause damage and mutations to DNA. Suppose you wished to study this further. You mate these rats and find that the offsprings have normal incidence of tumors. You would conclude that the tumors were most likely due to.

a. changes to somatic cells

b. changes in germ cells

c. changes to gonadal cells

If on the other hand the offspring also had increase tumor growth then you would conclude that the

a. tumor cells were passed down to offsprings

b. changes occur in stem cells

c. changes occur in germ cells

cell phones emit................ raditation when talking than on standby.

a. more

b. less

That would suggest that using a hands-free headset may be beneficial in preventing brain tumors. Ironically if the phone is kept in the pocket during a call using a headset then the genetic changes would be

a. prevented

b. more likely to pass to the next generation

c. less severe

Following are several transactions involving a university. In the current fiscal year, the university was notified by the federal government that next fiscal year it would receive a $500,000 grant for wetlands research. The university received a $500,000 endowment. For the fiscal year, the university recorded $2,500,000 in tuition and fees revenue. Cash refunds of $325,000 were given. The university provided $12,600 in tuition waivers for students with outstanding academic performance. During the year, the university constructed a new street, to allow for the expansion of its student housing efforts. The cost of the street was $1,980,000. The biology department spent $25,000 on wetlands research. At year-end, $1,670 of estimated uncollectible tuition and fees was recorded. Required Prepare journal entries to record the foregoing transactions, assuming the university is a private institution. (If no entry is required for a transaction/event, select "No Journal Entry Required" in the first account field.)Following are several transactions involving a university. In the current fiscal year, the university was notified by the federal government that next fiscal year it would receive a $500,000 grant for wetlands research. The university received a $500,000 endowment. For the fiscal year, the university recorded $2,500,000 in tuition and fees revenue. Cash refunds of $325,000 were given. The university provided $12,600 in tuition waivers for students with outstanding academic performance. During the year, the university constructed a new street, to allow for the expansion of its student housing efforts. The cost of the street was $1,980,000. The biology department spent $25,000 on wetlands research. At year-end, $1,670 of estimated uncollectible tuition and fees was recorded. Required Prepare journal entries to record the foregoing transactions, assuming the university is a private institution. (If no entry is required for a transaction/event, select "No Journal Entry Required" in the first account field.)

a. In the current fiscal year, the university was notified by the federal government that next fiscal year it would receive a $500,000 grant for wetlands research.

Note: Enter debits before credits.

b.The university received a $500,000 endowment.

Note: Enter debits before credits.

c. Record the receipt of tuition and fees revenue.

Note: Enter debits before credits.

Research two (2) publically traded U.S. companies, and download their financial statements. Assume that you are the CEO of one of the selected companies. You are responsible for gaining control over the other company. You have three (3) choices, either of which you believe that the Board of Directors will support. Choice 1: Your company acquires 35% of the voting stock of the target company. Choice 2: Your company acquires 51% of the voting stock of the target company. Choice 3: Your company acquires 100% of the voting stock of the target company.

1) Provide a brief background introduction on both the company that you are working for and the company that you are responsible for gaining control over.

2) Specify the overall manner in which the acquisition fits into your company’ strategic direction. Next, identify at least three (3) possible synergies that could occur as a result of the proposed acquisition.

3) Select two (2) out of the three (3) choices provided in the above scenario, and analyze the key accounting requirements for each of the two (2) choices that you selected. Next, suggest one (1) strategy in which you would prepare the financial statements for your company after the acquisition under each of the two (2) choices.

4) Select the choice that you consider to be the most advantageous to your company. Explain to the Board of Directors at least three (3) reasons why your selected choice is the most advantageous to the company.

5) Assume two (2) years after the acquisition, your Board of Directors wants to offer the shares back to the public in hopes of making a large profit. Assume that in each of the two (2) years your company and the target company have had exactly the same reported net income as they did in the year of acquisition. Determine the type of value, (e.g., cost of fair value) that you would use to report the subsidiary’s net asset in the subsidiary’s financial statements, which the company will distribute to the public with the public offering. Provide support for your rationale.

6) Use at least three (3) quality academic resources in this assignment. Note: Wikipedia and other Websites do not qualify as academic resources.

*no copying please

Business is becoming more and more competitive, and organisations have realised that purchasing and Supply Chain Management (SCM) are key factors in satisfying customers. Buyers and supply chain managers can contribute significantly to the organisation's profits. An organisation can spend as much as 50% of its sales revenue on purchasing parts, services, components and raw material. Therefore, efficient, mutually beneficial and constructive relationships with suppliers are very important to the organisation's short-term financial position and long-term competitive power.
1. The activities and objectives of different organisational buyers will dictate their purchasing needs and behavioural patterns with regard to purchases. Discuss the three types of organisational buyers. (10)
2. List and explain TEN criteria used to evaluate suppliers. (20)
3. Four critical factors have been identified for the successful implementation of a software-solution-driven SRM solution. Discuss these factors. (10)
4. Differentiate between constructive and competitive negotiation. (10)
5. Discuss the guidelines for maintaining positive supplier and customer relationships. (10)
Project Guidelines
 Your project should include a table of contents
 Text: Font: Arial or New Times Roman (12), spacing 1.5 lines
 All text must be justified at each margin
 The length of your answers to each question should be in line with mark allocations
 Your answers must include any theories, charts, tables or exhibits necessary to support your analysis and recommendations.
 Ensure that the readings are not merely reproduced in the project without original critical comments and views.
 References- At least 5 academic sources of reference must be used. (These include textbooks, journal articles and internet sources that are relevant to your field of study. Academic sources do not include Wikipedia and blogs). The MANCOSA study guide must not be used as a source of reference. You must include Reference list at the end of your project. Information quoted/paraphrased from sources listed in your Reference list must be referenced in-text. The Harvard system of referencing must be used.
 It is imperative that students proof read and edit their projects prior to submitting them. Projects must be free from errors and of a professional standard.

Patient Name: Arthur Tapping
Patient Number: 2004-1756-0
Birth Date: 12/07/72
Date: 07/07/04

Chief Complaint/ Present illness:
Mr. Tapping is a 32-year-old obese African-American male who visited the hospital with a chief complaint of postprandial gastralgia. The patient was well two weeks ago when he noticed the gradual onset of intermittent epigastric pain, after eating. Initially each episode lasted for ½ hour, was mild, and located diffusely in the upper abdomen. Over time the episodes lengthened to 1-2 hours, became severe, and localized in the RUQ. As of yesterday, he has vomited three times, and is now anorexic. The patient denies any previous history of abdominal pain, hemorrhoids, recent weight gain or loss, illicit drug use and excessive alcohol consumption. There are no suggestions of prior postprandial symptoms, or jaundice.

Physical Examination:
General: alert, responsive, middle-aged man who is moderately obese, in obvious discomfort.
Vitals: BP 173/80; Temp 98.5F; HR 97bpm;
Skin: clear, no evidence of jaundice
Lymphatics: unremarkable
HEENT: Sclera was icteric, ears, nose, and throat are clear
Chest: unremarkable
Abdomen: Moderately obese with a very tender globular mass in the RUQ. No splenomegaly or hepatomegaly noted on palpation. Rebound tenderness was negative over the RLQ. No ascites noted, or other evidence or portal hypertension. Bowels sounds are normal and no bruits noted.
Pelvic/Rectal: within normal limits, Guaiac negative, significant steatorrhea noted
Extremities: All distal pulses are palpable, no edema noted

Lab tests:
Blood: Within normal limits except for hypercholesterolemia, and hyperbilirubinemia
Urine: Bilirubin 3+
Echo scan gallbladder: Gallbladder is approximately 13 cm in length with four to five spherical calculi visualized each approximately 1.5 cm at their greatest diameter.
Impression:

1. Acute cholecystitis, from cholelithiasis
2. Secondary jaundice
3. Hypertension
4. Exogenous obesity
5. Hypercholesterolemia

Treatment/Plan: Refer patient to a gastroenterologist for an open cholecystectomy surgery with operative cholangiography.

Thomas Nosbod, MD

What surgery is suggested for Mr. Tapping?

Question 1 options:

Name: Mrs. JB

Medical Record #: N24669 Prepared by: KF

Date of Birth: 12/12/1942

Date of Presentation: April 17, 2005, 9:16pm

History and Physical Conducted: April 18, 2005 1-3am

Patient’s Room: 93

INFORMANTS:

1) Patient and daughter - fair reliability, poor insight

PATIENT PROFILE:

This is a 62 yo white female.

CHIEF COMPLAINT:

Headache, nausea, vomiting, and diarrhea

HISTORY OF PRESENT ILLNESS:

This 62 yo female with a PMH notable for TTP in 1996 who presents with intermittent dizziness, nausea, vomiting, and diarrhea of about 1 week duration. Over this period of time, she has been unable to take in any significant PO intake without vomiting. Her dizziness and lightheadedness are most notable when she stands up, and she has difficulty maintaining her balance due to this. She also notes that has been very tired for this past week, spending approximately 20 hours per day in bed sleeping. She denies pain, headache, fevers, chills, SOB, chest pain, hematemesis, bloody stool, tarry stool, dysuria, and increased bleeding or bruising. The patient is unable to provide further details or further describe her symptoms, and has no idea what might be causing them. She does deny any recent sick contacts, eating any new or abnormal foods, eating any potentially raw meats, and drinking large amounts of tonic water, or anything else that contains quinine.

PAST MEDICAL HISTORY:

1981 – Cesarean section. This was her fourth and final child.

August 1996 – 9 day hospital admission for TTP. Presented with nausea, vomiting, mental status changes, headache, and exertional dyspnea. After ruling out MI, meningitis, hepatic obstruction, renal insufficiency, and collagen vascular disease, the diagnosis of TTP was eventually made. Hospital course included 8 sessions of plasmapheresis, 4 sessions of hemodialysis, high dose IV steroids, and an open kidney biopsy which was complicated by a right pneumothorax.

January 2004 – Dilation and curettage for postmenopausal bleeding. In addition to these events, the patient has current diagnoses of HTN and hypercholesterolemia. She is unsure if she has CHF. Her baseline creatinine, at the time of her elective D&C in January 2004, was 1.7.

ALLERGIES/SENSITIVITIES:

NKDA

REVIEW OF SYSTEMS:

General –She has been excessively somnolent for the past week, sleeping through nearly the entire day. She has been experiencing a headache, lightheadedness, and has had a generalized feeling of dysphoria.

Skin – Patient points out that she has light scratch marks over much of her body where she has been scratching herself. This scratching has been going on for quite some time and is not new in the past week.

HEENT Eyes – The patient has blurry vision associated with her dizziness when she stands up. Otherwise, denies blurry vision, double vision, and any changes in visual acuity.

Nose/throat/mouth/teeth – Denies congestion, rhinorrhea, sore throat, and dental pain.

Respiratory – Denies dyspnea and cough.

Cardiovascular – Denies chest pain, palpitations, and peripheral edema.

Breasts – Denies changes, pain, and masses in breasts.

Gastrointestinal – Patient has diarrhea,

Genitourinary – Denies dysuria, polyuria, and hematuria.

Neurologic – Patient reports that she has had a headache for most of the time over the past week.

Hematopoietic – Denies easy bruising and bleeding. Denies any recent bruises or bleeding.

PHYSICAL EXAMINATION:

Skin – Several small, nonpalpable purpura on each upper arm. Two medium brown plaques on back with irregular borders.

Lymph nodes – No periauricular, cervical, supraclavicular, axillary lymphadenectomy.

HEENT – No scleral or sublingual icterus. Oropharynx clear, mucosa moist. Dentition absent.

No clonus, Reflexes – Patellar reflex appropriate bilaterally. Brachioradialis, brachial, and ulnar deep tendon reflexes are all hyperreflexive bilaterally. Babinski positive on right, negative on left.

ASSESSMENT/PLAN:

Thrombotic Thrombocytopenic Purpura (Hemolytic Uremic Syndrome)

Diagnostic Pentad:

Microangiopathic hemolytic anemia - This patient has a hemolytic anemia with a significant shistocytosis. The average shishtocytosis in TTP is 8.45% (with a range of 1% to 18%); her shistocytosis was 5%. Her elevated LDH is also confirmatory of her shistocytosis. On her admission for TTP in 1996, her renal biopsy showed a thrombotic microangioma. Thrombocytopenia, often with purpura – This patient does have a significant thrombocytopenia, with a platelet count of 66. In addition large platelets and clumping of platelets were noted on the peripheral blood smear, but of which are indicative of TTP. Some purpura were noted on physical exam, but they were not particularly prominent.

Acute renal insufficiency that may be associated with anuria – This patient has acute renal failure, with a BUN of 119 and a creatinine of 13.6. She is oliguric (about 30 cc/hour), but not anuric.

Fever – The patient has been afebrile by history.

Differential Diagnosis:

The main other diagnosis to consider in this clinical picture is diffuse intravascular coagulation (DIC).

Precipitating Factors:

Most cases of TTP are idiopathic.

Cancer – Neoplastic processes can precipitate TTP.

Treatment

Treatment for TTP is plasmapheresis and administration of fresh frozen plasma (FFP).

2) Acute Renal Failure

This patient has acute renal failure. The patient currently has no indications for dialysis, but we will continue to monitor for these indications, such as acidemia, altered mental status, dangerous

electrolyte abnormalities, volume overload, drug overdose, and symptomatic uremia.

3) Anemia

This patient is anemic, with a hematocrit of 0.34. This is a hemolytic anemia.

4) Thrombocytopenia

This patient is thrombocytopenic, with a platelet count of 66.

5) Diarrhea

The patient’s diarrhea appears to be fairly mild.

6) Hypertenison

The patient’s antihypertensives are currently being held to ensure adequate renal perfusion during her acute renal insufficiency.

7) Elevated transaminasaes

Her Lipitor will be held while she is in the hospital, because it may be complicating the clinical picture, and hypercholesterolemia is significantly less likely the cause morbidity or mortality while this patient is in the hospital than is her TTP.

9) Prophylaxis

KF

Find all medical terms in the following documents.