Need 600 Words long correct Answer:

Assignment: Choosing a drug delivery system for the best patient outcome

As a Pharmacist you have been asked to recommend a drug delivery system that can be administered for a patient. You will need to communicate to your peers and other healthcare providers why you have chosen this particular drug delivery system for this patient. You will need to:

A. Choose a disease state that you would like to research.

B. Decide on your patient profile/case study.

C. Justify your reasons why you have chosen this particular drug delivery system for your patient.

Tips and Hints:

Think about all the information we have covered in lectures about the choice of drug delivery system.

Research your chosen disease state and what pharmacotherapy is used.

Think clearly about your chosen case study

Which statement explains the MOST significant obstacle to solving global environmental problems?

There are significant differences of opinion among scientific experts about the level of environmental damage caused by certain practices.

The environmental effects of polluting practices are typically localized within the state where the pollution is created.

Enforcing environmental regulations can put a state at an economic disadvantage relative to nations where environmental damage goes unchecked.

Most environmental problems are too complex to be handled by traditional forms of government regulation.

Political leaders have few incentives to tackle problems that do not pose a direct economic threat to the state.

ONLY ONE ANSWER. Explain your choice

Explain the difference between ANOVA and ANCOVA in your own words. Both analysis tests are important but there are distinct differences. When is one used over the other?

Why is comparing two means an important part of the statistical analysis process? Give specific examples and explain in detail.

In your own word and answer in at least 5 sentence.

What does section 404 of the Sarbanes-Oxley Act require? What is the meaning of internal control? What are the five components of internal control? What are the four types of control activities?

Background: There are 4-5 pharmaceutical companies (mainly from China, Germany, and the USA) that are researching a cure/vaccine for corona – hopefully, one of these companies will have a solution for the world shortly– in the meantime, some governments are proposing for alternative treatments medicine like CHLOROQUINE (originally used to treat Malaria)

One company finally succeeds in producing the vaccine. Describe or explain in detail the following situations. ( 15 points ) :

a) What is the new market structure this Pharma company belongs to now ? Why ?

b) List the 5 market structure characteristics for a Monopoly and explain the relation to the Corona vaccine .

c) How does Initial supply and demand look like for the new vaccine? (what about initial elasticity and price ?)

d) How happens in Long term for supply and demand if new pharmaceutical companies find a similar vaccine ? (what about long term elasticity and price under the same conditions ?)

e) Describe what happens to Economic profits in the initial phase and the long term

f) Explain how the creative destruction concept applies (from Chloroquine to Corona vaccine) . Are there any benefits to everyone from having a Monopoly?

develop a proposal to create a vaccine for SARS-Cov2 (the virus causing Covid-19)

What do you expect the vaccine to do when introduced to the host?

2. Does everyone need to get the vaccine, why or why not?

3. To create a SARS-CoV2 vaccine, what viral component will you use as the vaccine to induce an immune response, and how will you obtain this information?

4. What system will you use to create the vaccine (use drawings as necessary)?

a. Detail the approach you will take to get an expression of your viral antigen?

b. How will you drive high expression of your viral antigen?

c. How will you produce large amounts of your vector vaccine?

Part I – Human ABO Blood Type

“But I already know all this stuff! I’ll do well on the test tomorrow, I promise,” begged Kevin. He really wanted to go out that night with his friend, but his mother had other ideas.

“No, absolutely not. You’re going to stay home and study; tomorrow’s test is very important,” his mother replied. Kevin ended up staying home that night, reluctantly.

The next day Kevin met his best friend Peter. “How’s it going?” asked Peter. “Not so good. We had a test today. I guess it went all right,” said Kevin. “How’s your stomach doing? Is it still sore?” Peter asked.

“Oh, it’s better now. You know, there’s something weird going on. Last time I was in the hospital, neither of my parents could donate blood to me. The doc said they aren’t a match for my blood type.”

“They don’t match? What do you mean?” Peter asked.

“Well, the doc said I’m type O positive, my mom is type A positive, and my dad is type B negative. We’re all different, and I don’t get it. They’re my parents—I mean, I should inherit my blood type from at least one of them, if not both, right?”

“That’s a good point,” Peter agreed. “Well, I’ve got a very cool science teacher, Ms. B. She would know better than us. Let’s ask her. She has a class tomorrow. We can meet her afterward. What do you say?”

The next day, Kevein and Peter met Ms. B. and explained Kevin’s puzzle about his family’s blood types.

“Ah, good question,” replied Ms. B. “Let me explain how blood types work so that it will help you to understand why your parents couldn’t donate blood to you and how you can all have different blood types in one and the same family.”

“The ABO blood group system is one of the most important systems that hospitals use to identify individuals for blood transfusion. ABO stands for the type of carbohydrate that sits on the surface of red blood cells; it’s this carbohydrate that allows cells to recognize themselves. They are also called surface markers. Positive (+) refers to the presence of Rhesus (Rh) factor. Some individuals lack Rh factor, and they are negative (−). Rh factor is a predominant protein surface marker on red blood cells.”

“Interesting. What is carbohydrate exactly? The stuff we eat, like bread and sugar?” Peter asked.

“Yes. Sugar is a carbohydrate and bread is made of lots of different carbohydrates. Red blood cells may have carbohydrate A on the cell surface, which results in type A blood; but if they have carbohydrate B, then they become type B blood. Some red blood cells have both carbohydrate A and B, which makes them have type AB blood. When neither carbohydrate A nor B is present on the red blood cell surface, the blood type is considered to be type O.”

That made sense to Peter, who then asked “How do red blood cells get those carbohydrates?”

“That’s a great question. The types of carbohydrate on the red blood cell surface are controlled by genes. In this case, the gene that controls carbohydrate types presented on red blood cell surface encodes enzymes. Enzymes are proteins that catalyze chemical reactions,” Ms. B. continued. “There are two types of such enzymes: enzyme A and enzyme

B, which deposit carbohydrate A and carbohydrate B respectively on the red blood cell surface. The three different versions of the gene are called alleles. Allele A codes for enzyme A; Allele B codes for enzyme B; Allele O doesn’t code for a functional protein.”

“Oh, then I must have O alleles since I’m type O!” Kevin was excited to figure out the alleles he had in his body.

Questions

1. What is the human ABO blood group system? What is the Rh system?
2. How are the RBC different from each type?
3. How many blood phenotypes are there in the ABO blood group system? Describe them

The Fundamental Forces govern interactions between all matter in the universe, yet we often don’t think about them in detail. Select one of the four Fundamental Forces and read about it in detail from at least one internet source apart from Wikipedia. You may start there for an overview. Write a few paragraphs summarizing the force you chose, and include anything interesting about it or its discovery that you wish to share.

Describe in detail methods used to quantify biodiversity. Use both soil and plant science concepts and itree in your answers.

please describe in two paragraphs.