An octapeptide was isolated from a fungus for use as a new antibiotic. The composition of the peptide was 2 Gly, Lys, Met, Pro, Arg, Trp, Tyr. Edman degradation of the intact peptide yields FDNB- glycine. The peptide was then treated with carboxypeptidase A, B and C, only carboxypeptidase C had any effect cleaving off Pro. The peptide was then treated with trypsin (cleaves at Arg and Lys), which gave two tripeptides and a dipeptide. The compositions of the tripeptides were Met, Lys, Tyr, and Arg, Trp, Gly. The peptide was digested with chymotrypsin (cleaves at Trp, Phe and Tyr), which yielded two tripeptides and a dipeptide. Acid hydrolysis of the dipeptide from chymotrypsin yielded only glycine (hint acid hydrolysis had two problems).
In: Biology
A researcher wants to investigate the bioactivity of a new drug.
Dosage Observations
|
20g |
26 |
28 |
37 |
30 |
|
30g |
427 |
49 |
36 |
405 |
|
40g |
42 |
47 |
52 |
38 |
In: Statistics and Probability
A company is looking for a new logo. As a manager of the company, you have been given the responsibility of generating ideas for the new logo and promoting it. What type of marketing strategies will you use to promote the logo?
In: Accounting
Assume that you are part of a development team that is working on a new warehouse management system. You have the task of investigating software packages that are available through ASPs. Using the World Wide Web, identify at least two potential sources of such software. What are the pros and cons of this approach to obtaining a software package?
Write in complete sentences. The answer may not exceed 100 words.
In: Computer Science
A company is looking for a new logo. As a manager of the company, you have been given the responsibility of generating ideas for the new logo and promoting it. What type of marketing strategies will you use to promote the logo?
give solution in 500 words.
In: Accounting
a. You are in the market for a new refrigerator for your company’s lounge, and you have narrowed the search down to two models. The energy-efficient model sells for ¢1,700 and will save you ¢45 in electricity costs at the end of each of the next five years. The standard model has features similar to the energy-efficient model but provides no future saving in electricity costs. It is priced at only ¢1,500. Assuming your opportunity cost of funds is 6 percent, which refrigerator should you purchase? b. You are the human resources manager for a famous retailer and are trying to convince the president of the company to change the structure of employee compensation. Currently, the company’s retail sales staff is paid a flat hourly wage of ¢20 per hour for each eight-hour shift worked. You propose a new pay structure whereby each sales- person in a store would be compensated ¢10 per hour, plus 1 percent of that store’s daily profits. Assume that, when run efficiently, each store’s maximum daily profits are ¢25,000. Outline the arguments that support your proposed plan.
In: Economics
An auto dealership is advertising that a new car with a sticker price of $34,128 is on sale for $25,995 if payment is made in full, or it can be financed at 0% interest for 72 months with a monthly payment of $474. Note that 72 payments × $474 per payment = $34,128, which is the sticker price of the car. By allowing you to pay for the car in a series of payments (starting one month from now) rather than $25,995 now, the dealer is effectively loaning you $25,995. If you choose the 0% financing option, what is the effective interest rate that the auto dealership is earning on your loan? (Hint: Discount the payments back to current dollars, and use Goal Seek to find the discount rate that makes the net present value of the payments = $25,995.)
Enter your answer as a percentage. If required, round your answer to one decimal digit.
| % |
In: Finance
In: Economics
You are considering the purchase of a new lathe to expand production of a hot product line. The lathe costs $280. It will have a life of four years. You will depreciate the lathe to zero book value using straight-line depreciation over four years. At the end of four years, you will sell the machine for $50. The new lathe will generate cash sales of $230 per year, and operating costs will run $120 per year. The firm will need to carry additional inventory of $30, accounts receivable of $30, and cash balances of $10. There is no material impact on accounts payable. The corporate tax rate is 40%. Assume the additional working capital requirements are incurred at the start of the project (t = 0) and are recovered in Year 4. The discount rate is 8%.
Assume all cash flows last for four years.
|
Description |
0 |
1 |
2 |
3 |
4 |
|
Description |
0 |
1 |
2 |
3 |
4 |
|
Total cash flow |
‒375.00 |
100.00 |
100.00 |
100.00 |
200.00 |
What are the NPV and IRR for the project? (Show calculations to receive full credit.) Should you invest in the project?
In: Finance
|
A firm is considering the purchase of a new machine at a price
of $108,000. The machine falls into the three-year MACRS
class. If the new machine is acquired, the firm's investment in net
working capital will immediately increase by $15,000 and then
remain at that level throughout the life of the project. At the end
of 3 years, the new machine can be sold for $5,000. Earnings before
depreciation, interest and taxes (EBDIT) are expected to be as
follows with respect to the new machine: Year 1: EBDIT = $55,000 The firm is subject to a 21 percent tax rate and the firm's discount rate is 8 percent. |
| Requirement 1: |
| Calculate the missing data in the table below for each year over the life of this project. (Do not round intermediate calculations. Round your answers to the nearest whole dollar (e.g., 32).) |
| Year | EBDIT | Depreciation | EBIT | Taxes |
| 1 | $55,000 | $ | $ | $ |
| 2 | $62,000 | $ | $ | $ |
| 3 | $87,000 | $ | $ | $ |
| Requirement 2: |
| What is the book value of the machine at the end of Year 3? (Do not round intermediate calculations. Round your answer to the nearest whole dollar (e.g., 32).) |
| Book Value (End of Year 3) | $ |
| Requirement 3: |
| Calculate the taxes related to the sale of the asset at the end of the project and the after-tax salvage value of the machine. (Do not round intermediate calculations. Net tax savings should be indicated by a minus sign. Round your answer to the nearest whole dollar (e.g., 32).) |
| Taxes | $ |
| After-Tax Salvage Value | $ |
| Requirement 4: |
|
What is the net cash flow of the project for each of the following years? (Do not round intermediate calculations. Net cash outflows should be indicated by a minus sign. Round your answers to the nearest whole dollar (e.g., 32).) |
| Year | Cash Flow |
| 0 | $ |
| 1 | |
| 2 | |
| 3 | |
| Requirement 5: |
|
What is the NPV of the project? (Enter rounded answer as directed, but do not use rounded numbers in intermediate calculations. Round your answer to 2 decimal places (e.g., 32.16).) |
| NPV | $ |
In: Finance