1. Antibiotic Evaluation

The following set of data was taken from tests of antibiotics on two organisms isolated from the lungs of a patient with Cystic Fibrosis. These evaluations were carried out using the disk diffusion method, and the diameter of the zone of inhibition (ZOI) is provided for each organism and antibiotic.

Pseudomonas aeruginosa is Gram-negative.

Corynebacterium xerosis is Gram-positive.

Resistant (R): ZOI ≤ 11 millimeters (mm)
Intermediate (I): ZOI > 11 mm and ≤ 17 mm
Sensitive (S): ZOI > 17 mm

Instructions: Evaluate the susceptibility of each organism to the antibiotics listed. Then, fill in the “Evaluation” columns with R, I, or S based on your analysis.

Based on the results from these two organisms and the data provided, determine which antibiotics are broad-spectrum and which antibiotics are narrow-spectrum.

2. Media preparation

2A. Of all the infectious agents we have discussed, at least one of them can remain pathogenic after going through a correctly-functioning autoclave. Which is it?

2B. To test our autoclaves at Southwestern we perform a monthly “Endospore viability” run. Explain why this is a good way to determine if the autoclave is working properly.

3. Estimation of Bacterial Population Size

3A. Estimate the population of the original culture based on the information below:

                Number of colonies on plate: 74
                Volume plated: 0.1 mL
                Dilution of culture plated: 1/1,000,000 (1 x 10^-6)

Estimated population density (Be sure to include the correct units!):

3B. If I took 0.5 mL of the original culture and diluted it into 15 mL of water, how much would the original culture be diluted?

3C. Suppose that I took 1 mL of water from Sweetwater Reservoir and plated it onto TSA. After 1 day of growth, I counted 30 colonies on the plate. Sweetwater Reservoir is estimated to have approximately

                34,000,000,000,000 milliliters of water (3.4 x 10¹³ mL)

How many bacteria do you estimate are living in Sweetwater Reservoir?

A company manufactures and sells x television sets per month. The monthly cost and​ price-demand equations are

​C(x)=75000+50x and p(x)=300-x/30, 0 ≤ x ≤ 9000

​(A) Find the maximum revenue.

​(B) Find the maximum​ profit, the production level that will realize the maximum​ profit, and the price the company should charge for each television set.

​(C) If the government decides to tax the company ​$5 for each set it​ produces, how many sets should the company manufacture each month to maximize its​ profit? What is the maximum​ profit? What should the company charge for each​ set?

The maintenance manager at a trucking company wants to build a regression model to forecast the time (in years) until the first engine overhaul based on four explanatory variables: (1) annual miles driven (in 1,000s of miles), (2) average load weight (in tons), (3) average driving speed (in mph), and (4) oil change interval (in 1,000s of miles). Based on driver logs and onboard computers, data have been obtained for a sample of 25 trucks. A portion of the data is shown in the accompanying table.

a. Estimate the regression model. (Negative values should be indicated by a minus sign. Round your answers to 4 decimal places.)

c. Based on part (a), are the signs of the regression coefficients logical?

Manage Your Health, Inc. (MYH) is a Fortune 500 company that provides a variety of healthcare services across the globe. MYH has more than 20,000 full-time employees and more than 5,000 part-time employees. MYH recently updated its strategic plan; key goals include reducing internal costs, increasing cross-selling of products, and exploiting new Web-based technologies to help employees, customers, and suppliers work together to improve the development and delivery of healthcare products and services. Below are some ideas the IT department has developed for supporting these strategic goals:

Recreation and Wellness Intranet Project: Provide an application on the current intranet to help employees improve their health. A recent study found that MYH, Inc. pays 20 percent more than the industry average for employee healthcare premiums, primarily due to the poor health of its employees. You believe that this application will help improve employee health within one year of its rollout so that you can negotiate lower health insurance premiums, providing net savings of at least $30/employee/year for full-time employees over the next four years. This application would include the following capabilities:

Allow employees to register for company-sponsored recreational programs, such as soccer, softball, bowling, jogging, and walking.

Allow employees to register for company-sponsored classes and programs to help them manage their weight, reduce stress, stop smoking, and manage other health-related issues.

Track data on employee involvement in these recreational and health-management programs.

Offer incentives for people to join the programs and do well in them (e.g., incentives for achieving weight goals, winning sports team competitions, etc.).

Health Coverage Costs Business Model: Develop an application to track employee healthcare expenses and company healthcare costs. Healthcare premiums continue to increase, and the company has changed insurance carriers several times in the past10 years. This application should allow business modeling of various scenarios as well as tracking and analyzing current and past employee healthcare expenses and company healthcare costs. This application must be secure and run on the current intranet so several managers and analysts can access it and download selected data for further analysis. The new application must also import data from the current systems that track employee expenses submitted to the company and the company’s costs to the insurance provider. You believe that having this data will help you revise policies concerning employee contributions to healthcare premiums and help you negotiate for lower premiums with insurance companies. You estimate that this application would save your company about $20/employee/year for full-time employees over the next four years and cost about $100,000 to develop.

Cross-Selling System: Develop an application to improve cross-selling to current customers. The current sales management system has separate sections for major product and service categories and different sales reps based on those products and services. You see great opportunities to increase sales to current customers by providing discounts when they purchase multiple products and services. You estimate that this system would increase profits by $1 million each year for the next three years and cost about $800,000 each year for development and maintenance.

Web-Enhanced Communications System: Develop a Web-based application to improve development and delivery of products and services. There are currently several incompatible systems related to the development and delivery of products and services to customers. This application would allow customers and suppliers to provide suggestions, enter orders, view the status and history of orders, and use electronic commerce capabilities to purchase and sell their products. You estimate that this system would save your company about $2 million each year for three years after implementation. You estimate that the system will take one year and $3 million to develop and require 20 percent of development costs each year to maintain.

Create a brief description of the project that you might implement in order to "improve employee health."

Propose at least two solutions for reducing health care costs.

What can might you do to initialize and plan for the project?

Identify the stakeholders in this project.

Propose methods for engaging stakeholders to increase project awareness and buy-in.

To increase project awareness, propose at least two methods of engaging stakeholders immediately.

For the comment below, someone did answer this on another question/answer posted. I am looking for a different view from the nursing standpoint as I believe this will be a medical/IT project. Answers to the bolded questions will be fine.

A large institutional investor is considering three Exchange Traded Funds:

Fund Expected Return Standard deviation Internet

ETF (Q) 11% 16%

Health Care ETF (H). 9% 12%

T-bill money-market ETF 4%

The two ETFs, Q and H are uncorrelated.

1. Find the proportions of each asset, and the expected return and standard deviation of the tangency portfolio.

2. What is the reward-to-variability (Sharpe) ratio of the best feasible capital allocation line?

3. Suppose this investor is highly risk averse with a risk aversion coefficient equals to 8. a. What is the composition of the optimal portfolio in terms of all available funds? b. What are the expected return and standard deviation of your optimal portfolio?

4. A less sophisticated investor would like to use only the Internet ETF and Health Care ETF, and require an expected return of 13%, what must be the investment proportions of her portfolio? Compare your result to the optimized portfolio in part 3.a. What do you conclude?

3. Problems and Applications Q3 Rosa and Alyssa are roommates. They spend most of their time studying (of course), but they leave some time for their favorite activities: making pizza and brewing root beer. Rosa takes 3 hours to brew a gallon of root beer and 2 hours to make a pizza. Alyssa takes 7 hours to brew a gallon of root beer and 5 hours to make a pizza. Rosa's opportunity cost of making a pizza is ? of root beer, and Alyssa's opportunity cost of making a pizza is ? of root beer. ? has an absolute advantage in making pizza, and ? has a comparative advantage in making pizza. If Rosa and Alyssa trade foods with each other, ? will trade away pizza in exchange for root beer. The price of pizza can be expressed in terms of gallons of root beer. The highest price at which pizza can be traded that would make both roommates better off is ? of root beer, and the lowest price that makes both roommates better off is ? of root beer per pizza.

The following cost functions apply to X Company's regular production and sales during the year:

  Cost of goods sold:   $6.05 (X) + $132,153

  Selling and administrative expenses:   $1.05 (X) + $76,167

where X is the number of units produced and sold. During the year, X Company sold 65,100 units for $19.00 each. At the end of the year, a company offered to buy 4,980 units but was only willing to pay $12.00 each. X Company had the capacity to produce the additional 4,980 units.

1. If X Company had accepted the special order, firm profits would have increased by?

2. Consider the following three changes. Direct material costs on the special order would have increased by $0.76 per unit, direct labor costs on the special order would have decreased by $0.49 per unit, and X Company would have had to rent special equipment for $1,500. Independent of your answer to (1), the effect of these changes would have been to reduce profit on the special order by?

3. In order to retain all of X Company's regular customers, it would have had to reduce the regular selling price by $0.59. If the selling price were reduced and next year's unit sales turned out to be the same as this year's sales, firm profits would have fallen by?

Preparation of bank reconciliation

The April 30, 2016, bank statement for Comet Company showed a cash balance of $7,582. The cash account in the company's general ledger (G/L), according to the company's records on April 30, had a balance of $4,643. The following additional data were revealed during the reconciliation process:

1.A deposit of $652 that had been made by the company on March 31 was processed by the bank in April, and a deposit of $1,531 made on April 30 had not yet been processed by the bank.

2.The bank statement listed a deposit for $360 that was mistakenly put in Comet Company's bank account; it should have gone to Comment Company's account.

3.Comet Company determined that there were three cheques that had not yet been processed by the bank: #466 for $1,250, #467 for $520, and #470 for $1,350.

4.The bank had collected a note receivable for $1,000 from one of Comet Company's customers. An additional $15 in interest had been added to its account.

5.The bank service charge for the month was $25.

Question:

a.  

Prepare a bank reconciliation for Comet Company as at April 30, 2016.

b.  

What cash balance should Comet Company report on its statement of financial position as at April 30, 2016?

c.  

Prepare the journal entries that are required to bring Comet Company's cash account to its correct balance.

1. A company contemplating the introduction of a new product wants to estimate the percentage of the market that this new product might capture. In a survey, random samples of 100 customers were asked whether or not they would purchase this new product. Fourteen responded affirmatively. The 90% confidence interval for the population proportion of potential customers that would purchase the new product is (0.08, 0.20).

a) Does the sample proportion lie in the interval (0.08, 0.20)? Yes/No?

b) Based on the scenario from the above question. Does the population proportion lie in the interval (0.08, 0.20)? Yes/No?

c) If we use a 95% confidence level instead of a 90% confidence level, will the confidence interval calculation from the same data produce an interval narrower than (0.08, 0.20)? Yes/No?

Lars Linken opened Lars Cleaners on March 1, 2017. During March, the following transactions were completed.

The chart of accounts for Lars Cleaners contains the following accounts: Cash, Accounts Receivable, Supplies, Prepaid Insurance, Prepaid Rent, Equipment, Accumulated Depreciation—Equipment, Accounts Payable, Salaries and Wages Payable, Notes Payable, Interest Payable, Common Stock, Retained Earnings, Dividends, Income Summary, Service Revenue, Maintenance and Repairs Expense, Supplies Expense, Depreciation Expense, Insurance Expense, Salaries and Wages Expense, Rent Expense, and Interest Expense.

Instructions

(a) Journalize the March transactions.

(b) Post to the ledger accounts. (Use T-accounts.)

(c) Prepare a trial balance at March 31.

(d) Journalize the following adjustments.

1. Services performed but unbilled and uncollected at March 31 was $200.

2. Depreciation on equipment for the month was $250.

3. One-sixth of the insurance expired.

4. An inventory count shows $280 of cleaning supplies on hand at March 31.

5. Accrued but unpaid employee salaries were $1,080.

6. One month of the prepaid rent has expired.

7. One month of interest expense related to the note payable has accrued and will be paid April 1.

(e)  Post adjusting entries to the T-accounts.