Compare the ATP yield of three glucose molecules that enter glycolysis and are converted to pyruvate with that of three glucose molecules that proceed through the pentose phosphate pathway such that their carbon skeletons (as two F6P and one GAP) reenter glycolysis and are metabolized to pyruvate. Indicate the steps where ATP was used or produced and the overall ATP totals.

Compare the ATP yield of three glucose molecules that enter glycolysis and are converted to pyruvate with that of three glucose molecules that proceed through the pentose phosphate pathway such that their carbon skeletons (as two F6P and one GAP) reenter glycolysis and are metabolized to pyruvate. Indicate the steps where ATP was used or produced and the overall ATP totals.

1. During cellular respiration, glucose is ______________.

Question 2

During cellular respiration, oxygen is ­­­­­­­­­­­­­­_______________.

Question 3

________________ is the breakdown of glucose into two molecules of pyruvate.

The _______________ is a series of carriers on the cristae of the mitochondria and extracts energy from NADH and FADH2 to produce molecules of ATP.

Question 5

The _______________ occurs in the matrix of the mitochondria and produces NADH and FADH2.

Problem 1. One of the consequences of ethanol addiction is fatty liver disease, an illness in which liver cells accumulate large amounts of triacylglycerols, the esters derived from glycerol and fatty acids. Ethanol is oxidized in the cytoplasm of liver cells by alcohol dehydrogenase and aldehyde dehydrogenase to yield acetate and 2 NADH. Acetate is then transported into the mitochondrion, where it is converted to acetyl-CoA and metabolized in the citric acid cycle.

1. Give a reason based on the products of ethanol metabolism and the electron transport chain for high energy charge in the cell
2. How would excess G6P concentration contribute to the reducing potential required for fatty acid synthesis?
3. How does acetate stimulate the rate of citrate formation based on enzyme kinetic?
4. How would the concentration of citrate in the mitochondria increase if the rate of isocitrate dehydrogenase rate were inhibited
5. What would inhibit the rate of isocitrate dehydrogenase if ethanol metabolism causes high-energy charge.

For the size of the baseball stadium, assume that we know that the mean size is 45000 and the population standard deviation to be 5800. What is the probability that the stadium size is between 43260 and 49000?

Select one:

a.

50.20%

b.

97.05%

c.

100%

d.

95.00%

The Assembly Department uses a process cost accounting system. The department adds materials and incurs conversion costs uniformly throughout the process. During May, $200,000 of materials costs and $95,000 in conversion costs were charged to the
department. The beginning Work in Process inventory was $63,000 on May 1, comprised of $40,000 of materials costs and $23,000 of conversion costs. The company employs the FIFO method of process costing.

Other data for the month of May are as follows:
Beginning Work in Process inventory, 5/1 25,000 units (40% complete)
Units completed and transferred out 50,000 units
Ending Work in Process inventory, 5/31 30,000 units (30% complete)

Fill in the blanks below based on the information above:

A. How many physical units have to be accounted for in May? [80000] units

B. What are the equivalent units of production for materials for the month of May? [49000] EUP​

C. What are the equivalent units of production for conversion costs for the month of May? [49000] EUP

D. What is the total cost assigned to one equivalent unit of production during the in May? $[6.02] rounded to the nearest $0.01.

E. Using the rounded result obtained in ‘D’ above, what is the total cost assigned to the 50,000 units that were transferred out of the Assembly Department in May? $[303800] rounded to the nearest $1

F. What is the total cost of the May 31 inventory? $[54180] rounded to the nearest $1

Suppose you are working in the National Microbiology Laboratory in Winnipeg, Manitoba, the Canada’s only containment Level 4 facility where scientist can work safely with COVID-19 (SARS-CoV-2). At this stage you are permitted to perform your experiments in normal human bronchial epithelial (NHBE) cells and mouse models.

3a) To combat COVID-19, can you design a CRISPR/Cas strategy by targeting SARS-CoV-2 in NHBE cells. (Genebank accession number for SARS-CoV-2 genome sequence is NC_045512)

3b) It is now known that the spike protein of SARS-CoV-2 attaches to the host receptor angiotensin-converting enzyme 2 (ACE2), which allows the coronavirus to enter human cells and replicate. To combat COVID-19, one approach is to knockout the human ACE2 protein, another is to enhance ACE2’s expression in NHBE cells. Can you choose ONE approach (NOT both) and describe how you would do it? (Human ACE2 gene GenBank: AB046569).
2
3c) It is debatable whether to use hydroxychloroquine (HCQ) to treat COVID-19 patients. To clarify it, could you design a single cell experiment to determine the transcriptome profiles of mice, which are infected with SARS-CoV-2 and treated with or without HCQ. (Note: mice (B6.Cg-Tg(K18-ACE2)2Prlmn/J) that express human ACE2 are from the Jackson Laboratory; CD4+ T cells, CD8+ T cells, B cells, and NK cells might be the focus).

7. Find the FIRST and FOLLOW sets for the grammar
S --> ABC
A --> a | Cb | ε
B --> c | dA | ε
C --> e | f

Construct LL(1) parsing table from grammar

1.) Evaluate the given definite integral.

Integral from 4 to 5 dA∫45 (0.2e^−0.2A +3/A) dA

2.) Evaluate the definite integral.

Integral from negative 1 to 1 dx∫−1 1 (x^2+1) dx

3.) Evaluate the definite integral.

Integral from 0 to 2 dx∫02 (2x^2+x+6) dx

4.) Evaluate the definite integral.

Integral from 1 to 4 left dx∫14 (x^3/2+x^1/2−x^−1/2) dx

5.) Evaluate the definite integral.

Integral from negative 2 to negative 1 dx∫−2−1 (3x^−4) dx