You have been contacted by the World Health Organization. Because you are a renowned microbiologist, they have asked you to join a panel of experts to come up with recommendations to curb the global problem of antibiotic resistance.  

Before the meeting, you need to draft a document outlining at least one recommendation in each of the following categories: 1) discovery of new antibiotics, 2) strategies to make ineffective antibiotics effective again, 3) ways to minimize the emergence and spread of resistance, and 4) methods to protect drugs of last resort.

Be sure to describe your strategy in detail, and specifically explain how your proposed strategies would address each category.

2. An experiment was conducted to test the effects of nitrogen fertilizer on lettuce production. Five rates of ammonium nitrate were applied to four replicate plots in a completely randomized design. The data are the number of heads of lettuce harvested from the plot. Use α =0.05

1. Write the statistical effects model and completely specify each component. State the necessary assumptions for the analysis.
2. Perform the appropriate analysis, identify what hypotheses are being tested, the test statistic, critical value and p-value. State your conclusions and make any specific recommendations for use of the fertilizers.
3. Use Tukey’s adjustment and perform pairwise comparisons for the different level of fertilizers.

4. Treatment (lb N/acre)	Heads of lettuce/plot
   0	104	114	90	140
   50	134	130	144	174
   100	146	142	152	156
   150	147	160	160	163
   200	131	148	154	163

Polyamorous relationships:

Discuss what you think are the strengths of these relationships and what you think are the weaknesses. Discuss this topic from a sociological point of view. Use your sociological imagination to think about and discuss whether or not this could become a social problem if everyone practiced it.  

1. The purchasing department employee works for meager wages and eventually conspires with the supplier contact to steal supplies for personal use. Which controls are adequate to deal with these types of situations?

2. Suggest controls you would recommend to mitigate these employee stealing for personl use. Eplain each suggestion in detail.

Please answer the following questions:

If Stan Sitwell had been open to George’s suggestion that they join forces, discuss two possible ways they could have acted that would be blatant violations of Section 1 of the Sherman Act.

If TBC had been able to raise the money to purchase Sitwell, what type of merger would it have been? Would the government have allowed the merger to proceed? (hint: discuss Section 7 of the Clayton Act).

Do George’s actions create an illegal monopoly under Section 2 of the Sherman Act? (hint: analyze ALL of the elements necessary to have an illegal monopoly).

Looking at Apple Corp. as the manufacturing company for computers and smartphones, explain how you would determine the company's contribution margin (CM) and contribution margin percent (CMP). In your initial post include the following:

• Identify which specific variables should be included in the calculation.
• Illustrate your explanation by calculating the contribution margin and contribution margin percent using hypothetical values.
• Explain what your calculated results tell you about the company’s sales and cost structure

Again, I am looking for these regarding a manufacturing company for smartphones and computers! Thank you.

Student,HW,Ex,Ex.Other
1,0.85,0.87,0.71
2,0.96,0.89,0.58
3,0.97,0.87,0.94
4,0.96,0.93,0.88
5,0.93,0.81,0.82
6,0.97,0.75,0.91
7,0.92,0.95,0.77
8,0.35,0.40,0.64
9,0.90,0.91,0.95
10,0.73,0.69,0.1
11,0.00,0.00,0.99
12,0.97,0.89,0.99
13,0.69,0.95,0.96
14,0.83,0.73,0.96
15,0.96,0.85,0.92
16,0.00,0.58,0.95
17,0.93,0.90,0.96
18,0.83,0.97,0.92
19,0.93,0.61,0.79
20,0.98,0.80,0.85
21,0.99,0.95,0.89
22,0.83,0.75,0.82
23,0.97,0.92,0.74
24,0.72,0.85,0.77
25,0.99,0.94,0.81
26,0.97,0.91,0.64
,,,
,,,
,,,
given the following values.

Please conduct a t test for the two ex grades.

#### a
Please check the conditions for a t test and state your assumptions.

#### b
What is the test statistic?

#### c
What is the p value?

#### d
Interpret the results in context.

#### e
Create a 95% Confidence Interval and explain the results.

#### f
Please explain why you did not complete a paired t test.

Shiraz, Inc. is a small producer and distributor of a product called Alpha. Shiraz Company has become interested in the preparation of operating and financial budgets. The budgets are vitally needed for operational planning and cost control purposes. You have been asked to assist Sara, the accountant of the company, in the preparation of budgets for the first three months of year 20X2.

Sales Forecasting:

Sara knows that the first step for the preparation of budgets is to forecast sales. Sara has been able to identify two possible variables that drive/influence the sales of the company. They are: the level of distribution of Alpha (number of dealers) and the amount of money spent on advertising (advertising expenditures). Sara wants to use the Regression method for the development of a regression equation/model for forecasting the sales of the company. She has accumulated 12 months of recent data, 20X1, on sales units, advertising expenditures, and the number of dealers as shown in Table I.

TABLE I

Shiraz expects the following for the first five months of year 20X2:

Budgeting:

Management of Shiraz Company is interested in a number of budgets. The preferred formats for budgets are displayed in Exhibit I. As shown in Exhibit I, Sara’s Excel file has two sections. Section One contains the required data for the preparation of budgets. Section Two contains the budgets. Since management of Shiraz wants to simulate the budgets for various possible conditions, the content of budgets will be stated all in formulas. The only area where data should be entered manually is in the data section, under the January column only! (Hint: this will require the use of excel functions including: “IF”, “AND”, “SUM”, “ROUNDUP”, “ROUNDDOWN”, “ROUND” etc.). Sara has prepared the following data for the preparation of budgets:

1. Sales

• Selling price per unit of Alpha is expected to be $12 in January through February. Five percent increase in selling price is expected in March. Aril and May are expected to have the same selling price as in March.
• Seventy-five (75) percent of each month’s sales are collected in the month of sale. The remaining is collected in the following month.

2. Manufacturing Expenses

Production of each Alpha requires:

• Direct materials: 5 pounds of direct material @ $0.80 per pound (expected to increase by 10 cents each month)
• Direct Labor: ½ hour of direct labor @ $10 per hour
• Variable manufacturing overhead (each unit): $0.50 per unit
• Fixed manufacturing overhead: Total of $25,000 per month of which $3,000 is depreciation expense

3. Operating (Selling & Administrative) Expenses

• Sales Commission: $0.80 per unit
• Shipping and Handling: $0.60 per unit
• Fixed Operating Expenses: Total $12,000 per month of which $1,500 is depreciation expense.

4. Payment of Expenses

• Other than purchase of materials, all expenses are expected to be paid in the month incurred. Sixty (60) percent of purchases are paid in the month of purchase and the remaining is paid in the following month

5. Capital Expenditures

• Shiraz is in the process of expansion of its operations by adding new equipment. The expansion requires $400,000 cash outflow in the month of January and another $200,000 in the month of February.

6. Loan Repayments & Interest Expense

• The Company can borrow from its bank as needed to bolster the Cash account. Borrowings and repayments of principle must be in multiples of $1,000, unless you are paying off the entire balance. All borrowings and repayments take place at the end of a month. The annual interest rate is 12%. Interest is compounded every month and added to the principle. Compute interest on whole month (1/12, 2/12, and so on).

7. Inventory Policy

• It is the company's policy to maintain an inventory of Alpha at the end of each month equal to 20% of next month's anticipated sales.
• Company also maintains an inventory of raw materials equal to 25% of next month’s production needs.

8. Other Information

• Sales on December of previous year were $4,350,000.
• Direct material purchases for December of the previous year were $1,800,000.
• The balance of cash on December 31 of the previous year was $21,000.
• The Company desires to maintain a minimum balance of $20,000 cash on hand at all times.
• Applicable income tax rate is 30%.

Requirements:

Write a one to two page single-spaced memo to the management of Shiraz Company and include/attach your findings.

1. In your memo, discuss these various equations and state which of the equations you would recommend to be used and why. Provide a complete and detailed justification for your choice. Also, discuss the meaning of the regression coefficients of the equation that you choose and explain whether these coefficients are reliable by referring each to its t-value. Attach your Excel work for this section to your memo. In your regression equation, carry two decimal points for coefficient of X variables and none for the intercept. (Hint: Your selection should be based on highest R² and t-values or P-values.)

1. Using the chosen equation in Item 1, forecast sales of Shiraz Company for January to May and state the results in a Table similar to the following in the memo. You may not be able to fill the cells for all 5 months. However, you should be able to have complete information for the first quarter (January, February, and March).

1. Using the format in Exhibit I, summarize the requisite data for the preparation of budgets in the January column of Section One of your Excel file. Then, write the necessary formulas for all other cells to calculate the budgets. Format nicely the content of budgets (allow two decimal points for “per unit” items and “round” to whole numbers for total items). Attach a print copy of (a) the budgets containing numbers, and (b) the budgets displaying the formulas in the cells (don’t worry about displaying the whole formula in order to save paper!)

5. There are rumors that the price of direct materials and direct labor for Alpha to be increased by 15% and 5%, respectively effective January 1, 20X2. Management of Shiraz wants to know the impact of this increase on its financial position. Recalculate the budgets by incorporating the expected increases in the price of direct materials and direct labor. Compute and discuss the percentages of change in the profit and cash balance of the company due to the increase in the price.

The Graduate Record Examination (GRE) is a standardized test commonly taken by graduate school applicants in the United States. The total score is comprised of three compo- nents: Quantitative Reasoning, Verbal Reasoning, and Analytical Writing. The first two components are scored from 130 - 170. The mean score for Verbal Reasoning section for all test takers was 151 with a standard deviation of 7, and the mean score for the Quantitative Reasoning was 153 with a standard deviation of 7.67. Suppose that both distributions are nearly normal. (a) A student scores 160 on the Verbal Reasoning section and 157 on the Quantitative Reasoning section. Relative to the scores of other students, which section did the student perform better on? (b) Calculate the student’s percentile scores for the two sections. What percent of test takers per- formed better on the Verbal Reasoning section? (c) Computethescoreofastudentwhoscoredinthe80thpercentileontheQuantitativeReasoning section. (d) Compute the score of a student who scored worse than 70% of the test takers on the Verbal Reasoning section.

The Graduate Record Examination (GRE) is a standardized test commonly taken by graduate school applicants in the United States. The total score is comprised of three compo- nents: Quantitative Reasoning, Verbal Reasoning, and Analytical Writing. The first two components are scored from 130 - 170. The mean score for Verbal Reasoning section for all test takers was 151 with a standard deviation of 7, and the mean score for the Quantitative Reasoning was 153 with a standard deviation of 7.67. Suppose that both distributions are nearly normal. (a) A student scores 160 on the Verbal Reasoning section and 157 on the Quantitative Reasoning section. Relative to the scores of other students, which section did the student perform better on? (b) Calculate the student’s percentile scores for the two sections. What percent of test takers per- formed better on the Verbal Reasoning section? (c) Computethescoreofastudentwhoscoredinthe80thpercentileontheQuantitativeReasoning section. (d) Compute the score of a student who scored worse than 70% of the test takers on the Verbal Reasoning section.