pH Dependence of Drug Absorption lab

1. Calculate the amount of Na₂HPO_{4 *} 7H₂O ( in grams) needed to make 50 mL of a 0.40 M solution.

2. Calculate the amounts of Na₂HPO₄ and NaH₂PO₄ (in grams) needed to prepare 200 mL of a buffer with pH=8.25 so that the sum of concentrations of HPO₄^2- and H₂PO₄^- ions is 0.5 M. pK_a1=2.12, pK_a2=7.21, pK_a3= 12.38

* on this problem I think you use the Henderson-Hasselbalch equation, but after that I'm lost.

3. Write the equation for the ionization of 3-aminophenol. Would this substance be more soulble in water at pH=2 or pH= 8? Would you expect this substance to be absorbed into the blood stream in the stomach or the instestines?

4. How does the initensity of the spot on the silica sheet relate to the solubility of the drug in the aqueous phase?

Please explain the the problems!!

A community is currently being served a single self-serve gas station with six pumps. A competitor is opening a new facility with 12 pumps across town. The table below shows the travel times in minutes from the four different areas in the community to the sites and the number of customers in each area.

(a) Using the Huff retail location model and if λ = 2, calculate the probability of a customer traveling from each area to each site.

(b) Estimate the proportion of the existing market lost to the new competitor.

Travel Times to Gas Stations (in minutes)

1. Which of the following is a valid alternative hypothesis for a one-sided hypothesis test about a population proportion p?

3. Nestlé is a manufacturer of dairy products. His administration conducted an analysis of the chocolate division. As part of this analysis, it has been determined that personal income, sales prices and advertising expenses are the three main variables that affect the demand for chocolates. It has been estimated that the income arc elasticity for chocolates is 1.5 and that the arc price elasticity of demand is -2.0, as well as the arc elasticity of advertising is .8

a) Using these elasticities and the data below, calculate the missing sales:

Year Income Price Advertising Sales
2016 $ 1000 $ 400 $ 120 850
2017 $ 1100 $ 400 $ 130
2018 $ 1100 $ 450 $ 140

b) The company also has information that reveals that a competitor plans to reduce the price of its chocolates from $ 500 to $ 381 a box by 2017. The marketing department has estimated that the cross elasticity between the two companies is 0.3. How will the quantity react? Nestlé defendant? (calculate)

1) Compared the lengths of the different Harry Potter movies and the Star Wars movies. Each series has 8 main movies that I will compare the lengths of. I will be testing my hypothesis that Harry Potter movies are longer than Star Wars movies.

The Harry Potter lengths in minutes are: 152, 161, 142, 157, 139, 153, 146, 130

The Star Wars lengths in minutes are: 133, 142, 140, 121, 124, 131, 138, 152

also:

2) The proportion of adults in Tennessee who are gamers is more than the proportion of adults in New York who are movie go-ers. In two independent polls, you may find that 69 out of 340 California residents are gamers and 59 out of 225 New York residents are movie go-ers.

Is there enough evidence to conclude that Tennessee residents game more than New York residents watch movies at the 0.8 significance level?

The probability is0.45 that a traffic fatality involves an intoxicated or​ alcohol-impaired driver or nonoccupant. In

seven traffic​ fatalities, find the probability that the​ number, Y, which involve an intoxicated or​ alcohol-impaired driver or nonoccupant is

a. exactly​ three; at least​ three; at most three.

b. between two and four​, inclusive.

c. Find and interpret the mean of the random variable Y.

d. Obtain the standard deviation of Y.

Assume that the duration of human pregnancies can be described by a Normal model with mean 268 days and standard deviation 14 days.

​a) What percentage of pregnancies should last between 274 and 281 days? (Round to two decimal places as needed.)

​b) At least how many days should the longest 25​% of all pregnancies​ last? (Round to one decimal place as needed.)

​c) Suppose a certain obstetrician is currently providing prenatal care to 58 pregnant women. Let y overbar represent the mean length of their pregnancies. According to the Central Limit​ Theorem, what's the distribution of this sample​ mean, y overbar​? Specify the​ model, mean, and standard deviation.

A. A normal model with mean ___ and standard deviation ___. (Type integers or decimals rounded to two decimal places as needed.)

B. A binomial model with ___ trials and a probability of success of ___. (Type integers or decimals rounded to two decimal places as needed.)

C. There is no model that fits this distribution.

​d) What's the probability that the mean duration of these​ patients' pregnancies will be less than

258 days?

- The probability that the mean duration of these patients' pregnancies will be less than 258 days is ___. (Round to four decimal places as needed.)

​days?

The relationship between the number of beers consumed in two hours (x) and blood alcohol content (y) was studied in 26 male college students by using least squares regression. The students studied consumed between 1 and 4 beers in the study. The following regression equation was obtained from this study:

yˆ=−0.0127+0.0180xy^=-0.0127+0.0180x

Answer the following (each is equally weighted):

1. Identify the explanatory and response variables.

2. According to the line of best fit, what would be the predicted blood alcohol content after consuming 3 beers in two hours? Round your answer to two decimal places, as needed.

3. Would it be appropriate to use this model to predict the blood alcohol content after seven beers? Why or why not (remember to include appropriate terminology).

The followings table gives information on GPAs (grade point average) and starting salaries (rounded to the nearest thousand dollars) of seven recent college graduates.  

1) Predict the starting salary for a student graduating with a 3.60 GPA. (Enter your answer in thousands of dollars rounded to two decimal places. Such as 12,345.67)

2) Predict the starting salary for a student graduating with a 2.10 GPA. (Enter your answer in thousands of dollars rounded to two decimal places. Such as 12,345.67)

3) Predict the starting salary for a student graduating with a 3.95 GPA. (Enter your answer in thousands of dollars rounded to two decimal places. Such as 12,345.67)

The followings table gives information on GPAs (grade point average) and starting salaries (rounded to the nearest thousand dollars) of seven recent college graduates.  

1) Predict the starting salary for a student graduating with a 3.60 GPA. (Enter your answer in thousands of dollars rounded to two decimal places. Such as 12,345.67)

2) Predict the starting salary for a student graduating with a 2.10 GPA. (Enter your answer in thousands of dollars rounded to two decimal places. Such as 12,345.67)

3) Predict the starting salary for a student graduating with a 3.95 GPA. (Enter your answer in thousands of dollars rounded to two decimal places. Such as 12,345.67)