Consider the function, f(x) = - x⁴ - 2x³ - 8x² - 5x

Use the golden section search (x_l = -2, x_u = 1, ε_s = 1%)

Overview Most disorders or diseases are caused by a combination of environmental and genetic factors. However, some are caused solely by genetics. We are going to examine the latter in this discussion. You will be given the choice of a genetic disorder to research and write about, and then you will draw some conclusions based on this information. You should spend approximately 3 hours on this assignment.

Instructions Choose one genetic disorder from the following list: Sickle cell anemia Cystic fibrosis Duchenne muscular dystrophy Achondroplasia

Conduct some research on the disorder you chose (remember to write down your sources). Start your discussion post with a description of the genetic disorder. Focus on the inheritance pattern of the disorder (autosomal dominant, X-linked, etc.) and the genotype and phenotype of a person with the disorder.

In your initial post, delve more deeply into the inheritance of the disorder by answering the following questions: What has changed in that gene to allow it to cause a genetic disorder? Be specific and explain how this differs from the gene’s normal function.

Is it possible for parents to not have the disorder, but pass it on to their children? What kind of dominance pattern does it show?

What problem(s) is/are caused to a person who inherits this gene? Is this gene typically inherited from the mother or the father? Finally, describe an experiment that you could use to determine if a new drug is effective at treating the disorder. Be sure to mention the independent, dependent and control variables

Finally, consider how you could use the scientific method to draw conclusions about this disorder or to treat this disorder.

Anytown Hospital has an outstanding reputation for surgical services. The operating room supervi- sor and a surgical nurse told Bob Wright, the CEO, that Dr. Flipton, an anesthesiologist, was abusing the use of anesthesia gases in the hospital’s dental suite. He was reportedly seen by operating staff testing “laughing gas” by holding a mask against his face for short periods of time. This scene would be followed by a string of silly, seemingly meaningless jokes. Bob has repeatedly discussed this matter with the medical executive committee. The medical executive committee refuses to take any action without definitive action by the department chair. Bob suspects that if he pursues the matter further with the governing board, he could end up without a job. The governing body is generally unable to resolve disciplinary actions against a physician without support of the medical executive committee.

What do you believe the ethical issues are for Bob knowing that doing the right thing and job survival could be in conflict? Which of the following would you do if you were in Bob’s position, with two children in college and hefty mortgage payments? Explain your answer in detail.

State Machines

Your state machine should decode the following serial bit patterns in the correct order, with one bit per clock cycle.

State Machine: 110110

Please do

a.    A state diagram

b.    An explanation of your design process. Be sure to include a reset or idle state

c.    The state machine description

d.    Your state assignments

e.    Your next state table

1. Provide a discussion regarding the scope of practice for Family Nurse Practitioners in California, including national guidelines, professional documents and/or state board rules and regulations.

2. Give two examples of patients that you would refer to a specialist and what criteria you would use to make this determination.

3. What education would you provide to your patient for why they are being referred to a specialist?

4. How would you determine follow up for your patient after the referral?

I know this is a lot but your assistance is much appreciated. Thank you.

Lucille and Lindsay are the owners of the two most successful jewelry stores in Orange County, CA. The two are constantly competing for sales and customers. In addition to operating a successful jewelry store, Lucille also writes a popular, widely circulated newsletter about things happening around town and local celebrities.

For the last few months, Lindsay has been consistently matching or beating Lucille’s prices and attracting customers with in-store events like live music and cocktail hour. In an attempt to win back customers, Lucille writes in her newsletter that Lindsay has been selling fake diamonds and gemstones and passing them off as the real thing. Lindsay’s jewelry business plummets and she is forced to close her store. She comes to you for legal advice. She wants to know:

(1) Does Lindsay have any legal claims against Lucille? If so, detail and explain the possible claims. (2) If so, is Lindsay entitled to any compensation from Lucille? Why or why not? (3) What possible defenses could Lucille raise?

In your answer don’t forget to: identify the legal issues presented by the facts of the question, define any relevant terms, and answer the question by applying legal reasoning (including naming the specific law or legal principle that applies).

Case Y X1 X2 X3 X4 X5 X6

1 43 45 92 61 39 30 51

2 63 47 73 63 54 51 64

3 71 48 88 76 69 68 70

4 61 35 86 54 47 45 63

5 81 47 85 71 66 56 78

6 43 34 51 54 44 49 55

7 58 35 70 66 56 42 67

8 71 41 64 70 57 50 75

9 72 31 81 71 69 72 82

10 67 41 78 62 49 45 61

11 64 34 65 58 60 53 53

12 67 41 72 59 41 47 60

13 69 25 61 55 44 57 62

14 68 35 75 59 47 83 83

15 77 46 75 79 74 54 77

16 81 36 52 60 74 50 90

17 74 63 77 79 71 64 85

18 65 60 78 55 77 65 60

19 65 46 83 75 59 46 70

20 50 52 76 64 56 68 58

1. What is the regression equation? (Perform a Multiple Regression Analysis and Paste the table in the first answer box.) 2. State the hypotheses to test for the significance of the independent factors. 3. Which independent factors are significant at alpha= 0.05? Explain. 4. State the hypotheses to test for the significance of the regression equation. Is the regression equation significant at alpha=0.05? Explain. 5. How much of the variability in Y is explained by your model? Explain. 6. What tools would you use to check if the model has multicollinearity problems? 7. Does this model have multicollinearity problems? Explain. 8. If you were to propose a simplified model, eliminating some variables, what would it be? Why? 9. What tools would you use to check if the model assumptions are met? 10. Does this model meet the assumptions? Explain.

Consider the following data:

1. What is the regression equation? (Perform a Multiple Regression Analysis and Paste the table in the first answer box.)

2. State the hypotheses to test for the significance of the independent factors.

3. Which independent factors are significant at alpha= 0.05? Explain.

4. State the hypotheses to test for the significance of the regression equation. Is the regression equation significant at alpha=0.05? Explain.

5. How much of the variability in Y is explained by your model? Explain.

6. What tools would you use to check if the model has multicollinearity problems?

7. Does this model have multicollinearity problems? Explain.

8. If you were to propose a simplified model, eliminating some variables, what would it be? Why?

9. What tools would you use to check if the model assumptions are met?

10. Does this model meet the assumptions? Explain.

An experiment consists of rolling an eight sided die and drawing a marble from a bag containing 3 blue, 5 red, 10 green, and 1 white. Let A be rolling an even number, B be drawing a green marble, C be rolling a number less than 4, and D be drawing a red or white marble. Write out each in words and find to the best of your ability.

(a) How big is the sample space and what are two ways to visualize it?

(b) P(A)

(c) P(A and C)

(d) P(A or C)

(e) P(A / C)

(f) P(A / B')

(g) P(B / D)

(h) P(A and D)

(i) P(A or D)

(j) Are any of the events mutually exclusive? Justify.

(k) Are any of the events independent from each other? Justify.

Star A is 3.2 times hotter than Star B. How many times brighter is Star A than Star B?

According to the Stefan-Boltzmann Law, a larger star will appear _________ than a smaller star of the same temperature.

brighter

bluer

redder

fainter

What is the peak wavelength of light coming from a star with a temperature of 4,300 K?
(Submit your answer in nanometers. Remember 1nm = 10^-9 m)

Sitting on the table is a red book and a blue book. Which one is hotter?

The blue book

They are probably the same temperature

The red book

Books are not blackbodies, so they do not emit radiation.

In order for an electron to move from one orbit to another, it must ...

emit or absorb light

increase in temperature

reach absolute zero

hit another electron