The United Nations Human Development Report gives the following data for real GDP per person in​ 2014: China,​ $12,547; Russia,​ $22,352; Canada,​ $42,155; United​ States, $52,947. Other information suggests that household production is similar in Canada and the United States and smaller than in China and Russia. The underground economy is larger in Russia and China and a similar proportion of each of these economies. Canadians and Americans enjoy more leisure hours than do the Chinese and Russians. Canada and the United States spend significantly more on the environment than do China and Russia. In which pair​ (or pairs) of countries is it easiest to compare the standard of​ living? And in which pair​ (or pairs) is it most​ difficult? Explain why. The standard of living can be easily compared​ ______. A. between China and Canada because they have a similar land size B. among all four countries because real GDP per person includes a reliable measure of​ income, household​ production, the underground​ economy, leisure​ hours, and the environment C. among none of the four countries because they are too different D. between Russia and the United States because they are both super powers E. between China and Russia or between Canada and the United​ States, because household​ production, the underground​ economy, leisure​ hours, and the environment are similar in each pair The standard of living cannot be easily compared in​ ______ and​ ______ because​ ______. A. ​China; Canada; one is much bigger than the other B. either China or​ Russia; either Canada or the United​ States; in each pair household​ production, the underground​ economy, leisure​ hours, and the environment are different C. ​Russia; China; because one is much bigger than the other D. either China or​ Russia; either Canada or the United​ States; in each pair the population densities are different E. ​Canada; the United​ States; one is much bigger than the other

Neurofibromatosis Type 1 (NF1) is a human genetic disorder. As well as physical symptoms, affected children often suffer from impaired cognition and learning. A cognitive task that involves solving a puzzle is administered to a group of children. For each child the time taken (in seconds) to solve the task is recorded. It is not known whether there is any suitable parametric model for the times so we will investigate non-parametric methods.

Carry out the Wilcoxon signed-rank test on these data to test the null hypothesis that the mean time to solve the puzzle for children with NF1 is the same as for healthy controls.

d) Calculate the value of the test statistic and give the approximate normal distribution of the test statistic under the null hypothesis.

e) Calculate the p-value for the test assuming a two-sided alternative hypothesis.

f) What do you conclude about the time taken by children with NF1 to solve the puzzle compared to healthy controls?

g) Describe in a few sentences how you would calculate a 95% confidence interval for the mean time without assuming any particular parametric model for the data. You do not need to calculate the interval.

The data below are the observed times ?? taken by 57 children with NF1.

Neurofibromatosis Type 1 (NF1) is a human genetic disorder. As well as physical symptoms, affected children often suffer from impaired cognition and learning. A cognitive task that involves solving a puzzle is administered to a group of children. For each child the time taken (in seconds) to solve the task is recorded.

It is not known whether there is any suitable parametric model for the times so we will investigate non-parametric methods.

1. Calculate appropriate summary statistics and thus give the parameters for a normal distribution that may be applicable to these data.

2. Using the observed data, calculate the empirical distribution function. Plot the empirical distribution function and the CDF of the normal distribution described in (a) on a single graph.

3. Do you think the normal distribution is an appropriate model for the data? Justify your answer.

It is known that the mean time to solve the puzzle in healthy control children is 60 seconds.

The data for the observed times ?? taken by 57 children with NF1 are:

The human body maintains its internal temperature through thermoregulation, and a healthy adult has a mean body temperature of 98.6 °F.

The processes of thermoregulation begin to deteriorate in older age, making it difficult to diagnose elderly patients who might have an illness. To understand the body temperature of elderly patients, researchers randomly sampled the body temperatures of elderly patients from a large database of medical records where the body temperatures were normally distributed.

Conduct a two‑tailed, one‑sample ?-test

to determine whether the mean body temperature of the elderly patients is different from that of a healthy adult using the sample data provided (in degrees Fahrenheit). Use a significance level of ?=0.05.

96.6,96.7,96.8,97.4,97.4,97.8,97.8,98.2,98.4,98.9

Shaver manufacturing, Inc. offers dental insurance to its employees. A recent study by the Human Resource Director shows the annual cost per employee per year followed the normal distribution, with a mean of $1 280 and the standard deviation of $420 per year. In all questions start with sketching a normal curve. Cross-hatch requested area/probability. If you calculate z-value, round it to two decimal places.

1. What was the cost for the 15% of employees that incurred the highest dental expense?
2. What was the range of annual dental costs (in dollars) for middle 80% of all employees?
3. What is the probability the employee’s annual dental costs are not exceeding $1200?
4. If random sample of 50 employees is chosen, what is the probability the sample is having a mean of $1100 or more?
5. If random sample of 95 employees is chosen, what is the probability the sample is having a mean between $1300 and $1400?

A. Answer Following questions.

1.A large number of class II promoters in the human genome lack TATA boxes. How does RNA Pol II recruitment differ between promoters with a TATA box and TATA-less promoters (2 pts)?

List 2 protein complexes that interact with the CTD of RNA Pol II during transcription

2. What class II gene(s) do not have a polyA tail (1pt)?

3.Polymerase recycling is an important mechanism for achieving high expression levels of a particular gene. What factors facilitate recycling (1pt), what regulatory step must occur (1 pt), why is this regulatory step important (1 pt)?

4.. Draw the 3’ Exon, Intron, and 5’ Exon after the first step of splicesomal intron splicing and before the second step. Be sure to show which components are connected (2 pts) and what the ends of the molecules look like- what are the functional groups at the ends (3pts).

5. If RNA Pol II incorporates the wrong nucleotide, what are the steps to relieve the pausing that results (3pts)?

6. Paused polymerases make excellent repressors. Describe which types of genes are likely to have paused polymerases- what is their expression profile (1pt). Why is a paused polymerase an excellent means to regulate these types of genes (3pts)?

7.List three functions of mediator in transcription (3 pts).

8. List two major findings from the ENCODE project (1pt).

9. Why do some people (not me) get upset if you call histone modifications “epigenetic marks” (2 pts)?

10. Where did Myc, Mad, and Max get their names? Besides the movie what do they stand for (2pts)?

You have been promoted to work as human resource manager for the ABC OVERSEAS COMPANY, you new job will be here in CANADA branch.

1.How will you achieve employment equity?

2.What are the variables of Canadian culture that you will realize at your new workplace?

3.Will this Organizational Culture impact positively on your new work environment? Why?

4.What can you do as a manager to improve employee engagement?with examples of your own?

How can we protect employment at Canadian workplace? Write in details.

Species: cat, lizard, human

1. For each of your species, describe how their morphology and/or behavior corresponds with their environment and way of life.

2. What ecological interactions do you observe or foresee between these species and their environment? Think about both interspecific and environmental interactions.

3. If one of these species were to be suddenly removed, what impact would this have on the ecosystem? How might this affect the survival and evolution of the other species you observed? How might this affect the environment? For this question, think beyond just the direct consequences and about the subsequent (or indirect) consequences this removal may cause as well (ie. cascade of cause and effect).

1. Cognitive biases related to human behaviour with respect to effective managers can be easily eliminated in the workplace. True or False

2. Corporate social responsibility (CSR)is limited to legal compliance with laws and regulations. True or False

3. Internal financial reports can provide important feedback to managers. True or False

4. An approach to improvement that involves completely redesigning business processes in order to eliminate any unnecessary steps is referred to as benchmarking. True or False

5. An organization prepares a code of ethics to meet its strategic goals. True or False

6. A manager who refuses to disclose confidential company data to friends demonstrates a high degree of confidentiality. True or False

7. If a management accountant is asked to engage in misleading accounting practices, and no resolution of the ethical dilemma seems possible, he/she should resign. True or False

8. Financial accounting requires greater precision than managerial accounting. True or False

9. An approach to improvement that involves completely redesigning business processes in order to eliminate any unnecessary steps is referred to as process reengineering. True or False

10. An accountant may produce both managerial and financial accounting reports. True or False

11. A chief financial officer's main function is to ensure that his/her company has sufficient operating capital.True or False

12. Budgeting is a planning function. True or False

13. Data that is objective and verifiable is said to be reliable. True or False

14. The process of selecting a course of action and specifying how the action will be implemented is referred to as

a) motivating

b) directing

c) planning

d) controlling

15.

Which one of the following is NOT an example of corporate social responsibility provided to customers?

a) Opportunities for training, promotion and personal development.

b) Safe, high- quality products that are fairly priced.

c) Easy to use information systems for shopping and tracking orders.

d) Full disclosure of product related risks.

16.

________ refers to human behaviour encouragement that comes from within us.

a) Cognitive biases

b) Intrinsic motivation

c) Benchmarking

d) Extrinsic motivation

17.

Both financial and managerial accounting rely on the same underlying financial data but there are major differences. Managerial Accounting:

A) must follow GAAP.

B) emphasizes relevance.

C) emphasizes financial consequences of past activities.

d) emphasizes precision.

18.

Managerial accounting focuses primarily on which of the following?

A) External financial reporting

B) Auditing the accounting data

C) Tax requirements

D) Internal decision making

19.

The process of mobilizing people to carry out plans and run routine operations is known as

A)planning

B) directing

C) directing and motivating

D) motivating

20.

After careful planning, Jammu Manufacturing Corporation has decided to switch to a just-in-time inventory system as a component of the lean thinking model. At the beginning of this switch, Jammu has 30 units of product in inventory. Jammu has 2,000 labour hours available in the first month of this switch. These hours could produce 500 units of product. Customer demand for this first month is 400 units. If just-in-time principles are correctly followed, how many units should Jammu plan to produce in the first month of the switch?

A) 370

B) 470

C) 400

D) 430