E. coli asparate transcarbamoylase (ATCase) has a Hill coefficient of 1.7 and Vmax 4.5 uM/min. The definition of Vmax is Kcat * [Etot], where kcat is the rate constant for formation of product. The measured value of kcat for this reaciton, which is determined in the absence of CTP, is 800 1/min. The dissociation constant for the allosteric effector CTP from ATCase is 1 mM. When CTP is bound to ATCase the K(1/2) for asparate is 20 mM; when CTP is not bound to ATCase the K(1/2) for asparate is 5 mM.

a) Calculate what the concentration of total ATCase is under the conditions where Vmax was determined. Calculate how much ATCase is present with CTP bound and how much is present without CTP bound when the CTP concentration is 6 mM. Calculate how much ATCase is present with CTP bound and how much is present without CTP bound when the CTP concentration is 0.3 mM.

Phillip? Witt, president of Witt Input? Devices, wishes to create a portfolio of local suppliers for his new line of keyboards. Suppose that Phillip is willing to use one local supplier and up to two more located in other territories within the country. This would reduce the probability of a? "super-event" that might shut down all suppliers at the same time at least 2 weeks to 0.3?%, but due to increased distance the annual costs for managing each of the distant suppliers would be ?$24 000 ?(still ?$16000 for the local? supplier). A total shutdown would cost the company approximately ?$450000. He estimates the? "unique-event" risk for any of the suppliers to be 4?%. Assuming that the local supplier would be the first one? chosen, how many suppliers should Witt Input Devices? use?

Find the EMV for alternatives using? 1, 2, or 3 suppliers.

Based on the EMV? value, the best choice is to use.

Your company has the sales for year 1 below. You want to select from one of three models for forecasting: a three-month moving average, a weighted moving average (you believe that the weights should be 0.2, 0.3, and 0.5), and an exponential smoothing average in which you use an alpha of 0.2 and an assumed forecast for January of year one of $35,000. Determine sales forecast for January year 2 and calculate MAD.


Jan Yr 1 34284
Feb 34000
Mar 31017
Apr 33406
May 34518
Jun 35469
Jul 35360
Aug 34894
Sep 34547
Oct 31015
Nov 31167
Dec 32925

A) Three-month moving average:
Sales forecast: $  
MAD:  

B) Weighted moving average:
Sales forecast: $  
MAD:  

C) Exponential moving average:
Sales forecast: $  
MAD:  

Which forecasting method should you use for your company? (enter A, B, C):

QUESTION ONE

1. Suppose the income increases from K50, 000 to K60, 000 and as a result consumption increases from K40, 000 to K47, 000 in Zambia. What is the marginal propensity to consume for the Zambian economy?                             [3 Marks]
2. Suppose the value of autonomous consumption is K40 000 and marginal propensity to consume is 0.6, estimate consumption at different levels of income: K0, K100, K200, K300, K400, and K500.                                               [6 Marks]
3. Given the consumption function in (b) above solve for the savings function and estimate savings at the different levels of income provided: K0, K100, K200, K300, K400, and K500.                                                                                          [8 Marks]
4. Fill the blank spaces.                                                                                       [8 Marks]

Use the following table to answer questions 1 - 6:

1. What is the expected return for asset A?

2. What is the expected return for asset B?

3. What is the standard deviation for asset A?

4. What is the standard deviation for asset B?

5. What is the expected return of a portfolio that has 70% in Asset A and 30% in Asset B?

6. The standard deviation of the 70% A and 30% B portfolio most likely should:

FINANCIAL LEVERAGE EFFECTS

The Neal Company wants to estimate next year's return on equity (ROE) under different financial leverage ratios. Neal's total capital is $17 million, it currently uses only common equity, it has no future plans to use preferred stock in its capital structure, and its federal-plus-state tax rate is 40%. The CFO has estimated next year's EBIT for three possible states of the world: $4.2 million with a 0.2 probability, $2 million with a 0.5 probability, and $0.9 million with a 0.3 probability. Calculate Neal's expected ROE, standard deviation, and coefficient of variation for each of the following debt-to-capital ratios. Do not round intermediate calculations. Round your answers to two decimal places at the end of the calculations.

Debt/Capital ratio is 0.

RÔE = %

σ = %

CV =

Debt/Capital ratio is 10%, interest rate is 9%.

RÔE = %

σ = %

CV =

The Neal Company wants to estimate next year's return on equity (ROE) under different financial leverage ratios. Neal's total capital is $12 million, it currently uses only common equity, it has no future plans to use preferred stock in its capital structure, and its federal-plus-state tax rate is 25%. The CFO has estimated next year's EBIT for three possible states of the world: $4.9 million with a 0.2 probability, $2.9 million with a 0.5 probability, and $700,000 with a 0.3 probability. Calculate Neal's expected ROE, standard deviation, and coefficient of variation for each of the following debt-to-capital ratios. Do not round intermediate calculations. Round your answers to two decimal places.

Debt/Capital ratio is 50%, interest rate is 11%.

Debt/Capital ratio is 60%, interest rate is 14%.

National Corporation has semiannual bonds outstanding with nine years to maturity and the bonds are currently priced at $754.08. If the bonds have a coupon rate of 7.25 percent, then what is t

he after-tax cost of debt for Beckham if its marginal tax rate is 30 percent? Solution

• Number of periods = 9 * 2 = 18

  Coupon = (0.0725 * 1000) / 2 = 36.25

  Yield to maturity = 11.7499%

  Keys to use in a financial calculator: 2nd I/Y 2, FV 1000, PMT 36.25, PV -754.08, N 18, CPT I/Y

  After tax cost of debt = YTM (1 - tax)

  After tax cost of debt = 0.117499 (1 - 0.3)

  After tax cost of debt = 0.0822 or 8.22%

HOW DID THEY FIND THE  Yield to maturity = 11.7499%

HOW CAN I DO THIS PROBLEM BY HAND STEP BY STEP OR BY FINANCE CALCULATOR STEP BY STEP ?? PLEASE HELP

Human Development Data Set: Questions are posted in next post.

You are provided with data for several nations from the Human Development Report, 2017.

1. Compute summary statistics (mean, median, mode, standard deviation etc.) for the variables of GDP (GDP per capita in thousands of dollars) and Internet use.

Provide descriptions of the distributions based on the summary statistics. Address skewness in your description.

2. Generate a scatterplot with clearly labeled axes CO2 and GDP. CO2 will be on the Y axis. Comment on what you see.
3. Compute the correlation between CO2 and GDP and interpret it. Refer to both the strength and direction of the correlation in your interpretation.
4. Using the variable Internet Use, construct the 1^st, 2^nd, and 3^rd standard deviation from the mean intervals and calculate the percentages for each. Then make a short interpretation on whether they match the percentages in the Empirical Rule.