Consider the final reaction in the citric acid cycle, catalyzed by malate dehydrogenase:

Malate + NAD+  ⇄ oxaloacetate + NADH + H+

Equilibrium concentrations of the reaction components were measured as follows:

[malate] = 5.28 mM

[NAD+] = 75 uM

[oxaloacetate] = 14.5 uM

[NADH] = 14.5 uM

pH = 8.83

a) From these data calculate the equilibrium constant, Keq, for this reaction.

b) Calculate the standard free-energy change, ΔG°’, for this reaction (hint: remember that

the prime means that the standard [H+] is 1.0 × 10-7 M, not 1 M)

c) Calculate the actual free-energy, ΔG, under the following conditions:

 [malate] = 6.0 mM

[NAD+] = 100 uM

[oxaloacetate] = 0.001 uM

[NADH] = 0.0001 uM

pH = 8.83

M/P = 24 + 0.8Y ? 400r

C =2+0.8(Y?T)?200r

I =30?200r
NX =24?0.1Y?2e
Y =C +I +G+NX

You are given the following values for various variables: rw = 0.05; M/P = 100;G = 10 and the budget is balanced. Using the model, find the values for Y, e and the components of demand. Verify that the values you found for consumption, investment and net exports satisfy the goods-market equilibrium condition, given the value of G. Finally, suppose that the nominal exchange rate ( enom ) is 0.8

and the foreign price level ( PFor ) is 1.0. Use this information to find the domestic price level and the nominal value of the money supply (M).

Two 10-cm-diameter charged rings face each other, 19 cm apart. The left ring is charged to -30 nC and the right ring is charged to +30 nC .

Part A

What is the magnitude of the electric field E⃗  at the midpoint between the two rings?

Express your answer to two significant figures and include the appropriate units.

Part B

What is the direction of the electric field E⃗  at the midpoint between the two rings?

What is the direction of the electric field  at the midpoint between the two rings?

Part C

What is the magnitude of the force F⃗  on a -1.0 nC charge placed at the midpoint?

Express your answer to two significant figures and include the appropriate units.

Our environment is very sensitive to the amount of ozone in the upper atmosphere. The level of ozone normally found is 4.8 parts/million (ppm). A researcher believes that the current ozone level is at an excess level. The mean of 6 samples is 5.0 ppm with a standard deviation of 1.0. Does the data support the claim at the 0.05 level? Assume the population distribution is approximately normal.

Step 1 of 5 :  

State the null and alternative hypotheses.

Find the value of the test statistic. Round your answer to three decimal places.

Specify if the test is one-tailed or two-tailed.

Determine the decision rule for rejecting the null hypothesis. Round your answer to three decimal places.

Make the decision to reject or fail to reject the null hypothesis.

QUESTION 9

Tony Hawk is skating through a half-pipe with a radius of 4 m. Initially he is in a crouched position with his center of mass 0.5 m above the surface of the half-pipe. He starts from rest with his center of mass a height of 3 m above the base of the half-pipe and experiences no loss of energy from friction as he moves. At the bottom of the half-pipe he stands up and lifts his arms into the air, thereby raising his center of mass to 1.0 m. He then continues up the other side of the half-pipe. What is the maximum height (in m) that his center of mass reaches on the other side of the half-pipe? You may model Tony as a point particle.

Saturated propane vapor at 200 psia is fed to a well-insulated heat exchanger at a rate of 2600 standard cubic feet per hour. The propane leaves the exchanger as a saturated liquid (a liquid at its boiling point) at the same pressure. Cooling water enters the exchanger at 70 oF. Flowing concurrently (in the same direction) with the propane. The temperature difference between the outlet streams (liquid propane and water) is 15 oF.

Estimate the required flow rate (lbm/h) of the water to take away the heat from exchanger. (you will need to write two separate energy balances.) Assume the heat capacity of liquid water is constant at 1.0 Btu/(lbm.oF) and neglect heat losses to the outside and the effects of pressure on the heat of evaporation of propane.

Consider the he kinetics data below. Note that two reactions were studied. Use the information to calculate the EQUILIBRIUM CONSTANT for

            2 NOCl (g) -> 2NO(g) + Cl₂  

                                                                        [NO]               [Cl₂]                initial rate

                                                                        0.10M             0.10M             0.54M/s

                                                                        0.10M             0.20M             1.05M/s

2NO(g) + Cl₂(g) -> 2NOCl(g)                    0.10M             0.30M             1.62M/s

                                                                        0.10M             0.40M             2.16M/s

                                                                        0.20M             0.50M             10.8 M/s

                                                                        0.30M             0.50M             24.3 M/s

                                                                        0.40M             0.50M             43.2 M/s

[NOCl]            time

5.00M             0s

4.55M             5.0 x 10⁵s

2NOCl(g) -> 2NO(g) +   Cl₂(g)                   4.174M           1.0 x 10⁶s

3.855M           1.5 x 10⁶s

3.582M           2.0 x 10⁶s

14-E1. Below are some (fictitious) correlations between all pairs of three variables. The means and standard deviations are also give. Imagine that they were obtained from a sample of 35 randomly chosen individuals.

1. Which, if any, of these correlations are significantly different from zero?
2. What does "significantly different from zero" mean in simple words?
3. How large a sample of individuals would be required for a correlation of 0.1 to be significant?
4. If the units of Age changed to months then which figures would change and how?

CASE SCENARIO:

An 80 year-old woman fell in her home. She is evaluated in the emergency room and is found to have a hip fracture. She was recently started with hydrocholorothiazide to treat her hypertension. She has been on an SSRI for depression following the loss of her husband and is taking NSAIDs for pain associated with osteoarthritis. Her vitals are stable. She is lethargic and disoriented but otherwise appears well. Laboratory works reveals Na – 105 mEq/L, K – 3.2 mEq/L, BUN – 32 mg/dL, Creatinine – 1.0 mg/dL.

1. Develop a Nursing care plan (ADPIRE, Assessment, Diagnosis, Planning-short term and long term goal, Intervention-Rationale, Evaluation) for this patient based on the scenario