Questions
In studying receptor-ligand interactions, the researcher wanted to narrow down the exact region of binding between...

In studying receptor-ligand interactions, the researcher wanted to narrow down the exact region of binding between the receptor and the ligand. Amino acids 24 – 29 on the receptor were believed to be involved in ligand binding. So the researcher performed mutations in these amino acids and assayed the effect of these mutations by performing binding assays. Mutation amino acid 24​   Receptor-Ligand binding. No

If the amino acid 24 was mutated from a glycine to an arginine, and the binding assay results were negative, what would you conclude from these results about the role of this amino acid in binding to the ligand? (1 point)

Explain in detail and also suggest other amino acid changes that would help understand these results further.

In: Biology

You heard in the news that Bank of Canada has just lowered the policy overnight rate...

You heard in the news that Bank of Canada has just lowered the policy overnight rate to 0.25% due to the economic catastrophy of Corornavirus.

  1. Does this signal the Bank is moving to to more expansionary or contractionary monetary policy? Explain in detail.

  1. In your opinion why did the bank lowered the policy overnight rate?

In: Finance

Give two practical examples on applications of predictive analytics in your area (e.g. supply chain or...

Give two practical examples on applications of predictive analytics in your area (e.g. supply chain or IT or Library or etc.). Provide detail explanations. You need to explain why you think predictive analytics can be used in those cases, you do not need to provide data or solve them

In: Statistics and Probability

Contrast the neoclassical economic theory with the new economic theories (new endogenous growth theory, new economic...

Contrast the neoclassical economic theory with the new economic theories (new endogenous growth theory, new economic geography, and strategic trade theory)? Do the new economic theories reject the neoclassical economic theory? Substantiate your arguments with real world case(s) and example(s). ( Explain it in detail)

In: Economics

state the four quantum numbers then explain the possible values they may have and what they...

state the four quantum numbers then explain the possible values they may have and what they actually represent

In: Chemistry

Explain what it is a neutral theorem in Euclidean geometry. State & prove both: the theorem...

Explain what it is a neutral theorem in Euclidean geometry.
State & prove both: the theorem on construction of parallel lines and its converse. Which one of them is neutral?

In: Advanced Math

In 200 words Explain the four indicators of the balanced scorecard, and state what a strategy...

In 200 words Explain the four indicators of the balanced scorecard, and state what a strategy map is?

In: Operations Management

Explain what is meant by a welfare state. Discuss recent trends in the size of welfare...

Explain what is meant by a welfare state. Discuss recent trends in the size of welfare states.

In: Psychology

36. Explain what the technique known as soft state is and how it applies to ARP...

36. Explain what the technique known as soft state is and how it applies to ARP and the ARP cache.

In: Computer Science

5. (a)A sample of 12 of bags of Calbie Chips were weighed (to the nearest gram),...

5. (a)A sample of 12 of bags of Calbie Chips were weighed (to the nearest gram), and listed, here as follows.

219, 226, 217, 224, 223, 216, 221, 228, 215, 229, 225, 229 Find a 95% confidence interval for the mean mass of bags of Calbie Chips.

[9 marks]

(b) Professor GeniusAtCalculus has two lecture sections (A and B) of the same 4th year Advanced Calculus (AMA 4301) course in Semester 2. She wants to investigate whether section A students maybe ”smarter” than section B students by comparing their perfor- mances in the midterm test. A random sample of 12 students were taken from section A, with mean midterm test score of 78.8 and standard deviation 8.5; and a random sample of 9 students were taken from section B, with mean midterm test score of 86 and standard deviation 9.3. Assume the population standard deviations of midterm test scores for both sections are the same. Construct the 90% confidence interval for the difference in midterm test scores of the two sections. Based on the sample midterm test scores from the two sections, can Professor GeniusAtCalculus conclude that there is any evidence that one section of students are ”smarter” than the other section? Justify your conclusions.

[8 marks]

(c) The COVID-19 (coronavirus) mortality rate of a country is defined as the ratio of the number of deaths due to COVID-19 divided by the number of (confirmed) cases of COVID-19 in that country. Suppose we want to investigate if there is any difference between the COVID-19 mortality rate in the US and the UK. On April 18, 2020, out of a sample of 671,493 cases of COVID-19 in the US, there was 33,288 deaths; and out of a sample of 109,754 cases of COVID-19 in the UK, there was 14,606 deaths. What is the 92% confidence interval in the true difference in the mortality rates between the two countries? What can you conclude about the difference in the mortality rates between the US and the UK? Justify your conclusions. [8 marks]

In: Statistics and Probability