in detail how is energy stored in pyruvate converted into adenosine triphosphate (ATP) in eukaryotic cells?

please explain with lots of detail as I am struggling to understand this concept. :(

thanks in advance.

Below is the data for a personality questionnaire measuring conscientiousness. These data were taken from a random sample of 25 undergraduate psychology majors. In the general population, scores on this questionnaire are normally distributed with a mean (μ) of 60. You hypothesize that this sample is not representative of the general population. Specifically, you hypothesize that psychology students form a distinct sub-population, with DIFFERENT conscientiousness, relative to the general population. That is, it would be equally interesting to find out they have higher or lower conscientiousness. Conduct a one-sample t-test by answering the following questions.

Data: N = 25, xbar (sample mean) = 65.12, S_x = 10.17

  a. State the null and alternative hypotheses.

  b. Are you going to be using a one- or two-tailed test? Explain the reason for your choice.

  c. What are the degrees of freedom for this t-test? Find the corresponding critical t-value for Type I error rate (alpha) of α = 0.05?

d. Calculate your observed t-statistic.

e. Compare your observed t-statistic to the critical t-value(s). What do you conclude regarding the null hypothesis?

f. Calculate and interpret follow-up 95% Confidence interval

g. Calculate and interpret the standardized effect size (Cohen's d).

h. What do you conclude about your research question (use your own words, in everyday language)

7) Your partner is ready to use a gene drive to eradicate Zika. Your partner is proposing a flowchart for his experiment but she jumbled up his lab and field protocols. Place the following, applicable statements in order:

(Example: d x f …. Etc..)

Answer:   ______ _______ ______ _____ ______   ______ ______ ______ _____ _____

A) Identify freshly emerging recombinant mosquitos that glow red under the fluorescent microscope.

B) After a few months do DNA tests on wild life and mosquitos on the island and find only very few (if any) Dengue-positive specimens.

C) Sit back in your beach chair, smile, and think of the fame that will be yours for eradicating Zika. What could possibly go wrong?

D) In the Lab, show that recombinant mosquito offspring can feed on mice carrying the Zika virus but afterwards do not carry the Zika virus themselves.

E) Show that the mosquito’s offspring also glow red and now contain the original gRNA, Cas9, and a monobody to the Zika pathogen.

F) On an uninhabited, tropical offshore island infested with Zika virus release hundreds of recombinant, red-eyed mosquitos.

G) Generate an expression construct with the matching gRNA, Cas9, RFP and a monobody to the Zika virus.

H) Rear the recombinant mosquitos on laboratory mice, let them grow and mate with wild-type mosquitoes.

I) Search the database to identify a Zika virus target sequence with a juxtaposed PAM

K) Micro-inject the construct into developing mosquito larva.

7) Your partner is ready to use a gene drive to eradicate Zika. Your partner is proposing a flowchart for his experiment but she jumbled up his lab and field protocols. Place the following, applicable statements in order: (Example: d x f …. Etc..) Answer: ______ _______ ______ _____ ______ ______ ______ ______ _____ _____

A) Identify freshly emerging recombinant mosquitos that glow red under the fluorescent microscope.

B) After a few months do DNA tests on wild life and mosquitos on the island and find only very few (if any) Dengue-positive specimens.

C) Sit back in your beach chair, smile, and think of the fame that will be yours for eradicating Zika. What could possibly go wrong?

D) In the Lab, show that recombinant mosquito offspring can feed on mice carrying the Zika virus but afterwards do not carry the Zika virus themselves.

E) Show that the mosquito’s offspring also glow red and now contain the original gRNA, Cas9, and a monobody to the Zika pathogen.

F) On an uninhabited, tropical offshore island infested with Zika virus release hundreds of recombinant, red-eyed mosquitos.

G) Generate an expression construct with the matching gRNA, Cas9, RFP and a monobody to the Zika virus.

H) Rear the recombinant mosquitos on laboratory mice, let them grow and mate with wild-type mosquitoes.

I) Search the database to identify a Zika virus target sequence with a juxtaposed PAM

K) Micro-inject the construct into developing mosquito larva.

Due: 07/25/2018
Bonus Assignment #1

Directions: For this bonus assignment, you will give a presentation on a statistical model of your choosing. To do this, choose a statistical model from the list below and come up with a hypothetical study related to your research interests that could be conducted using the model. Presentations should be 5-6 minutes and must include the following:
Background information on your topic, research question/hypothesis, and why you think your study should be conducted.
State the IV (including levels) and the DV. Be specific about what your variables are. Review “operational definitions” in your textbook. Also, mention the scale of measurement your variables are measured on.
Explain what the procedure would be for individuals participating in your study. BE SPECIFIC ABOUT EACH STEP IN THE PROCEDURE.
Come up with a sample data set for your hypothetical study (minimum of 30 data points total). Demonstrate how the data would be analyzed using the model in JMP*. You can obtain a free copy of JMP using your student id information here: (http://helpdesk.louisiana.edu/sasjmp).
Explain how to interpret the results of the test. Relate your analysis to the question posed by your hypothetical study.
Choose from the following statistical models:
One-way between-subjects ANOVA
One-way within-subjects ANOVA
Two-way between-subjects ANOVA
Regression
*Two-way ANOVA does not require a JMP demonstration.

TEST CORRECTIONS 5. In a study on the benefits of eating organic produce, fruit flies were assigned at random to two groups. One group was fed organic potatoes and the other was fed conventional potatoes. At the end of 13 days, the porportion of flies that were still alive was calculated for each group. To address the question of whether more flies would survive eating organic potatoes than conventional potatoes, we use the hypothesis HO: Porganic = Pconventional vs HA: Porganic > Pconventional

Part A: (got this right)

Part B: Suppose our primary concern is to protect the pubic from potentially harmful pesticides, as found in conventional potatues, and that if no statistically significant difference is found from this test, a grocery chain will stop selling organic potatoes. Is it safer to use a large or small significance level here? Explain in detail.

Part C: The p-value for the data in this study is 0.017. What is the conclusion of the test? State the conclusion in detailed context, using non-technical language.

Part D: A very large sample of fruit flies was used for this study. In the end, 35.8% of the flies eating organic potatoes were still alive, compared to 35.4% of the flies eating conventional potatoes. Comment on the PRACTICAL SIGNIFICANCE of this result. Make a clear distinction between practical and statistical significance.

You are a Health & safety Specialist. The date is March 12th 2020 and the world Health Organization has just announced that COVID-19 is a world pandemic the day before. The CEO of the company you work at has called you into her office and requested that you come up with a plan to deal with this issue. She has been hearing about staff complaining that the company is not doing enough to protect them. She asks you to come up with a policy to take care of these trouble makers . She wants you to have something in place to deal with the virus problem and with the complaints. You go back to your office and ponder what to do. State what your course of action would be. How would you go about addressing this request? What are the issues you need to think about as you come up with your policy recommendation? Do not create the policy; just state all the factors you need to consider. Keep in mind that you have CHRP and CRSP designations. The CEO does not.

500 words for this case study.

Question:-6 people were randomly selected and their systolic (x) and diastolic (y) blood pressures were measured. Systolic 138 130 135 140 120 125 Diastolic 92 91 100 100 80 90 Σx = 788, Σy = 553, Σx 2 = 103794, Σy 2 = 51245, Σxy = 72876 (Data)

(A)If systolic blood pressure increases by one unit, then:-

(a) diastolic blood pressure decreases by about 15.5 units

b) diastolic blood pressure decreases by about 0.82 units.

(c) diastolic blood pressure increases by about 15.5 units

(d) diastolic blood pressure increases by about 0.82 units

(e) the response of the diastolic blood pressure cannot be predicted (Explain in detail how..??)

You are playing a version of the roulette game, where the pockets are from 0 to 10 and even numbers are red and odd numbers are black (0 is green). You spin 3 times and add up the values you see. What is the probability that you get a total of 15 given on the first spin you spin a 2? What about a 3?

Solve by simulation and analytically.