In humans, the RH factor and elliptocytosis genes are located on the same chromosome at 3% from each other. The color blindness gene and the night blindness gene are located 40% apart on the X chromosome. Rhesus positivity and elliptocytes - dominant alleles, and night and color blindness are recessive.

А) A woman who was heterozygous in all her genes and whose ancestors had no crossing over was married to a man who suffered from night blindness and color blindness, with Rh-negative blood and normal red blood cells. Determine the probability of birth in this family of a boy with color blindness, RH positive blood and normal red blood cells.

B) A Heterozygous woman with all genes, whose mother suffered from elliptocytosis and night blindness, and whose father had Rh-negative blood and suffered from color blindness, married a man suffering from night and color blindness, with Rh-negative blood and normal red blood cells. Determine the probability of birth in this family of a girl with normal vision blindness, Rh-negative blood and without elliptocytosis.

You are an EMT and are called to the home of an 11 week old infant boy who has become listless and is having trouble breathing. The parents state that the infant has not been smiling lately, nor has he had other noticeable facial expressions in the last couple of days. The baby's eyes are open when you arrive but he does not seem to be able to focus. You place your outstretched finger under his fingers and he is not able to grasp it. You lift his foot and it falls back down onto the mattress. The parents also state that he has not had a bowel movement in the past 3 days.

1. What is your suspicion, based on what seem to be nervous system symptoms?

2. If your suspicion is correct, should you start treatment here or should he be trasnported to the hospital?

3. What should be administered to the baby at the earliest opportunity?

4. How do babies acquire this condition?

5. Is this same condition seen in adults? If so, explain any similiarities or differences in the symptoms.

As a pediatric immunologist, you have two patients both around a year old with similar but distinct symptoms. Both patients have hypothyroidism, and you have prescribed synthetic thyroid hormone to each. One patient, a girl aged 5 years, has had recurrent thrush infections (yeast infection of the mouth). And the other, a boy aged 18 months, has had several outbreaks of eczema. Family histories show male and female relatives with similar issues or worse for your female patient, and males relatives with similar issues for the male patient. You begin to suspect a heritable autoimmune disorder. (a) Which autoimmune disorders do you think each one has and why (at least 2 reasons for each) (abbreviations for diseases is ok). (b) What gene is defective in each disorder? And how would you test or confirm your diagnoses in part (a)? (c) Your partner suggests that both children should get bone marrow transplants. Do you agree? Why or why not in each case?

Discussion Board 3.1: Communicating with Patient's Records

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Discussion:

Communication is the key to a successful interaction with a patient. However, there can be challenges along the way. Age, culture, and education all play an important role in how people respond to your care.  

Objectives:

• To understand how to communicate with people in the medical environment under unusual circumstances.

Instructions:

Respond to the following: Choose one of the communication issues below and explain what issues you may have with communicating with this patient and how you can overcome these issues. Make sure you cite at least 2 outside sources for your solution to the issue

• You are working with a family of a young autistic child
• You are working with an elderly person who has comprehension issues/dementia
• You are working in the inner city with a person who has an 8th-grade education
• You are working with an Orthodox Jewish woman/man ( opposite sex)
• You have a 3-year-old child and both her parents
• You have a 16-year-old boy with his mother in the lab

A 19-year-old African American male living in an upper-middle class suburban neighborhood in Fremont, California, reported that he was stopped and questioned four times in two weeks by different officers. On one occasion, the conversation went this way:

Officer: What are you doing here?

Teen: I’m jogging, sir.

Officer: Why are you in this neighborhood?

Teen: I live here sir.

Officer: Where?

Teen: Over there, in that big house on the hill.

Officer: Can you prove that? Show me your I.D.

On another occasion, when he was jogging, a different officer stopped him and asked (referring to the very expensive jogging shoes he was wearing), “Where did you get those shoes?” When the boy answered that he had bought them, the next question was, “Where do you live?” When the teen answered, “in that big house on the hill,” the officer apologized and went on his way.

How can community policing be incorporated into this community to meet the needs of a better community-policing partnership?

Suppose the industry of all farms planting beans is now in a perfectly competitive longrun equilibrium, and all farms have zero fixed cost for planting. Recent regulation in the market of fertilizers raises the price of bean fertilizer and therefore the marginal and average costs of all the farms in this industry. Note that marginal and average cost curves both experience a parallel shift up by the same amount. Please use a graphic tool to analyze the following changes to each individual farm and to the entire industry:

(a) Set up a diagram, for both individual firms and the industry, to show the longrun equilibrium before the fertilizer shortage. Clearly mark the market price (p), individual supply (q), and the industry supply (Q).

(b) Suppose the fertilizer shortage takes place but the price for beans has not yet adjusted accordingly (no entry or exit either). How much will each existing farm produce (mark your answer as q1 on the same graph) and how much profit or loss are they getting (make with a shaded area on your graph)?

(c) As time goes by, will this industry experience any entry or exit? How will the price start to adjust? Explain your answer. Mark on your graph the new long-run industry supply, the new equilibrium market price (p’), the new individual supply (q’), and the new industry supply (Q’).

The Acme Widget Company has generally followed a relative conservative business model and has done well. Their sales have been relatively stable over the past decade and represent about 40% of the powered widget market, with widgets operating on conventional fossil fuels – gasoline, diesel, and propane. One of the founders of the company recently passed on his voting stock to his son, who advocates moving the company in a new direction. He wants the company to pursue a new business opportunity with the design and manufacture of widgets that employ alternative energy sources. You have been hired as a consulting engineer by the company to help them decide if they should go forward. While you know next to nothing about powered widgets, they believe you can help them perform an objective RWW analysis.  

Describe in some detail how you would go about leading this analysis: what questions would you have for the company personnel, what other sources of data might you want to use and what information would you attempt to gather from these sources? Incorporate as many of the tools we have explored this semester as you feel apply. For example: Is the Design for X Spiderweb graphic relevant for this analysis? What role might forecasting techniques play? How important is it to be able to quantify various factors at each stage of the analysis?

On June 28, 1990, an important decision was rendered with regard to a lawsuit between Lotus Development Corporation, the creator of the Lotus 1-2-3 spreadsheet, and Paperback International, the creator of the VP-Planner spreadsheet. Lotus had sued Paperback International for infringement of its copyright on Lotus 1-2-3. Paperback had copied the entire menu structure of the Lotus 1-2-3 program. The manual of the VP-Planner even contained the following statement: ‘’VP-Planner is designed to work like Lotus, 1-2-3, keystroke for keystroke . . .. VP Planner’s worksheet is a feature-for-feature work alike for the 1-2-3. It does micros. It has the same command tree. It allows the same kind of calculations, the same kind of numerical information. Everything 1-2-3 does, VP-Planner does.’’ Paperback, in turn, alleged that only the part of a computer program written in some computer language, such as C, is copyrightable. It argued that the more graphic parts of a program, such as the overall organization of the program, the structure of the program’s command system, the menu, and the general presentation of information on the screen, are not copyrightable. Lotus countered by arguing that copyright protection extends to all elements of a computer program that embody original expression.
Question: Could Lotus 1-2-3 be protected by a copyright and patent? Why or why not? (10 points)