A 67-year-old man presents to your office with worsening cough, sputum production, and shortness of
breath. He is a smoker for the past 50 years. He is known to have Chronic Obstructive Pulmonary
Diseases (COPD). He was in his usual state of health until one week ago until he got a common cold and
since then he has a hacking cough and increased sputum production. this is all information I have

1. What are the two major clinical disorders/diseases are classified as Chronic Obstructive
Pulmonary -Diseases? How do they differ?

2. Which one of the two syndromes above is more predominant in this patient? What is the
predisposing factors for the syndrome from the scenario?

3. Asthma is considered one of the obstructive disease of pulmonary diseases, explain the
the pathological mechanism that is responsible for asthma that causes the asthma attack.

Finance - CFIN 6th Edition Chapter 14, Problem 12 Solution

I am not able to come up with the same solution posted in the Chegg Study Textbook solution for this question beginning with step 4 of 7. The issue has to do with computing the EAR. I followed the textbook solution, but the response does not make sense for the EAR. Please help.

Chapter 14 Problem 12

Montana Allied Products (MAP) must borrow $1.7 million to finance its working capital requirements. The bank has offered a 45-day simple interest loan with a quoted interest rate of 8 percent. Calculate the loan’s APR and assuming there is (a) no compensating balance requirement and (b) a 15 percent compensating balance requirement, which MAP must satisfy from the loan proceeds. (c) How much does MAP have to borrow so that it has $1.7 million to pay its bills if the loan requires a 15 percent compensating balance?

The formula and the solution provided does not match up

(1+8/360)^8-1

Picture Maker is a free-standing photo kiosk consumers use to download their digital photos and make prints. Shashi Sharma has a small business that leases several Picture Makers from the manufacturer for $120 per month per kiosk, and she places them in high-traffic retail locations. Customers pay $0.18 per print. (The kiosk only makes six- by eight-inch prints.) Sharma has one kiosk located in the Sanchez Drug Store, for which Sharma pays Sanchez $80 per month rent. Sharma checks each of her kiosks every few days, refilling the photographic paper and chemicals, and collects the money. Sharma hires a service company that cleans the machine, replaces any worn or defective parts, and resets the kiosk's settings to ensure the kiosk continues to provide high-quality prints. This maintenance is performed monthly and is independent of the number of prints made during the month. The average cost of the service runs about $90 per month, but it can vary depending on the extent of repairs and parts required to maintain the equipment.

Paper and chemicals are variable costs, and maintenance, equipment lease, and store rent are fixed costs. If the kiosk is malfunctioning and the print quality deteriorates, Sanchez refunds the customer's money and then gets his money back from Sharma when she comes by to check the paper and chemical supplies. These occasional refunds cause her variable costs per print for paper and chemicals to vary over time.

The following table reports the results from operating the kiosk at the Sanchez Drug Store last month. Budget variances are computed as the difference between actual and budgeted amounts. An unfavorable variance (U) exists when actual revenues fall short of budget or when actual expenses exceed the budget. Last month, the kiosk had a net loss of $23, which was $87 more than budgeted.

Required:

1. Prepare a schedule that shows the budget Sharma used in calculating the variances in the preceding report.

2) (10 point question) Many people love colorful and tasty tomatoes and an ambitious student in horticulture wants to breed such a tomato variety. He searched all the available tomato genetic resources, and found the two inbred lines he needed. One line produces the tomatoes with a colorful red-green-yellow mosaic pattern (rrTT), and the other strain is 'very tasty' (RRtt).

When the student crossed the two strains together, he made the following observations:

In the F1 generation, all the ripe tomatoes have a regular red color and a regular flavor. The student tasted tomatoes from over 40 individual plants, and was sick with regular tasting tomatoes.

In the F2 progeny, the student sampled 1000 tomato plants: 498 had red-color tomatoes with normal taste, 248 colorful tomatoes with normal taste, and 254 red-color tomatoes with great taste. He was disappointed not to find any colorful tomatoes with great taste. He then sampled another 2000 F2 plants: 998 had red-color tomatoes with normal taste, 511 colorful tomatoes with normal taste, 488 red-color tomatoes with great taste, and 3 colorful tomatoes with great taste; he was so happy to find what he wanted!!!

Based on these experimental results, he realized that the alleles he needs are recessive and the two genes are linked.

A) (4 points) How closely linked are the r and t genes? Please explain your strategy to calculate the distance.

B) (2 points) A testcross with the F1 can be used to further define the genetic distance between the two genes. Indicate the ratio of progeny phenotypes that you'd expect (describe phenotypes) from this cross based on the map distance you propose for part a).

C) (2 points) The tomato genome has now been sequenced and genes on the chromosome are in the following order OPQRSTU. The respective physical distances on the chromosome between these seven genes are very similar. But we now know that there is a 'cold spot' between genes RT and 'hot spots' between PQ and TU. Draw a representation of the genetic map relative to the physical map (both maps are needed here) for this part of the tomato genome. Show the relative (approximate) locations of the genes on the two maps.

D) (2 points) What can you predict about the chromosome chromatin structure between the R and T genes?

1. A psychologist is interested in the relationship between intelligence and academic motivation. She recruits eight participants for a study. Each participant completes an intelligence test and a measure of academic motivation. Scores for the eight participants are in the table below. Use intelligence scores to predict motivation scores with regression analysis by hand.

1. Calculate the slope coefficient.

2. Calculate the intercept.

3. Write out the prediction equation and write one sentence interpreting the slope.

4. Calculate the standard error of the estimate.

5. Use the regression equation to predict a motivation score and then calculate its 95% confidence interval when intelligence is 50. Is this an appropriate prediction to make? Briefly explain why or why not.

6. Use the regression equation to predict a motivation score and then calculate its 95% confidence interval when intelligence is 65. Is this an appropriate prediction to make? Briefly explain why or why not.

7. Does the regression model significantly predict motivation scores? (H₀: β = 0; H₁: β ≠ 0, α = .05) Provide the test statistic, appropriate degrees of freedom, and whether p is greater than or less than α. (Note: there are two ways that you can use to test model significance.)

4. (20 pts) GA Industries manufactures handling equipment used in distribution centers. One product, called a Liftmaster, has three components: a frame with strap, a motor and two supports. The most recent order has been for 4000 Liftmasters for next month. The sales and production departments must work together to determine delivery schedules. Although the processes used in the manufacture of the three components vary, there are three areas where the production manager is concerned about the availability of resources. These three areas, their usage by the three components, and their availability are detailed in the table.

A quick look at the amounts available confirms that GA does not have the resources to fill this contract. A subcontractor, who can make an unlimited number of each of the three components, quotes the prices below.

The subcontractor requires that the minimum purchase of frame is 600. Due to their production capacity onstraint, the subcontractor can only supply up to 2500 motors.

Develop a linear programming model that would tell GA how to fill the order for 4000 Liftmasters at the minimum cost.

It is observed that 56.00 mL of water at 20∘C completely fills a container to the brim. When the container and the water are heated to 60∘C, 0.35 g of water is lost.

Part A

What is the coefficient of volume expansion of the container? Density of water at 60 ∘C is 0.98324 g/mL.

Express your answer using two significant figures.

Part B

What is the most likely material of the container?

You are considering a project that offers up the following possible payout with an opportunity cost of 20%.

Time 0 1 2

Base Case -$60,000 10,000 10,000

At the end of year two you know there is a 10% possiblity you will buy out your competitor which has the potential to create opportunities that are worth $1,028,231 at that time. How much potential value is created or lost by taking on this project (i.e. what is the NPV)?

Two equal mass object experience a totally inelastic elastic collision. Mass 1 has an initial velocity of 10 m/s in the negative y-direction. Mass 2 has an initial velocity of 10 m/s in the positive x-direction. The collision occurs at the origin. What is the magnitude and direction of the velocity of the combined mass? What is the kinetic energy conserved in the collision? If not what fraction of kinetic energy was lost?